ZUTRIPRO ORAL SOLUTION CII
Generic Name and Formulations:
Hydrocodone bitartrate 5mg, chlorpheniramine maleate 4mg, pseudoephedrine hydrochloride 60mg; per 5mL; grape-flavor.
Indications for ZUTRIPRO ORAL SOLUTION:
Cough and nasal congestion associated with upper-respiratory allergies or common cold.
Use accurate measuring device. ≥18yrs: 5mL every 4–6hrs as needed. Max: 4 doses (20mL) per 24hrs.
<18yrs: not established.
During or within 14 days of MAOIs. Narrow angle glaucoma. Urinary retention. Severe hypertension. Severe coronary artery disease.
Risks from concomitant use with benzodiazepines or other CNS depressants.
Risks from concomitant benzodiazepines or other CNS depressants (see Interactions). Discontinue if respiratory depression occurs. Abuse potential (monitor). Avoid in head injury, other intracranial lesions or pre-existing increase in intracranial pressure. Acute abdomen. Cardiovascular disorders. Diabetes. Thyroid disorders. Addison's disease. Prostatic hypertrophy. Urethral stricture. Asthma. Severe hepatic or renal impairment. Elderly. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.
Antitussive + antihistamine + sympathomimetic.
See Contraindications. Increased risk of respiratory depression, sedation with benzodiazepines or other CNS depressants (eg, opioids, antihistamines, antipsychotics, anxiolytics, alcohol); avoid. Hypertensive crisis with MAOIs. May affect or be affected by TCAs. Paralytic ileus may occur with anticholinergics
Sedation, somnolence, mental clouding, lethargy, impairment of mental and physical performance, anxiety, fear, dysphoria, dizziness, psychic dependence, mood changes, nervousness or sleeplessness, visual disturbances, confusion, headache, euphoria, facial dyskinesia, feeling faint, lightheadedness, agitation, restlessness, insomnia, irritability, tremor; respiratory depression, cardiovascular effects.
Clinical Pain Advisor Articles
- Manual Therapy vs Opioids for Management of Shoulder, Spine Pain
- Kinesiophobia May Be Associated With Greater Cutaneous Allodynia in Migraine
- Intervention by Pharmacists May Effectively Reduce Use of Inappropriate Medications in the Elderly
- PainDETECT May Not Be Optimal to Detect Neuropathic Components of Orofacial Pain
- Topical Migraine Trigger Point Treatment as Effective as Injection
- Serum Vitamin D Levels and Risk for Migraine
- Rimegepant Orally Dissolving Formulation Provides Rapid Relief From Acute Migraine
- Updated Evidence-Based Recommendations for Buprenorphine Treatment
- Prescription Digital Therapeutic Approved for Opioid Use Disorder
- Persistence of Post-Traumatic CRPS Associated With Initial Pain Sensitization
- Blunted Cardiovascular Stress Reactivity in Fibromyalgia With Comorbid PTSD
- Name-Brand Medications Driving Spike in U.S. Drug Spending
- Physician Responsibility to Combat "Fake News" in Medicine
- The Future Of Robot Physicians: Is Artificial Intelligence Poised to Take Over Medicine?
- Chronic Spinal Pain and Depression: Does One Represent a Risk Factor for the Other?