Withdrawal

Lofexidine Effective for Opioid Withdrawal Symptoms

Lofexidine Effective for Opioid Withdrawal Symptoms

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Investigators pooled data from 2 phase 3 placebo-controlled studies to evaluate the safety and efficacy of lofexidine for opioid withdrawal symptoms.

Buprenorphine Injections Effective on Opioid-Associated Euphoria and Withdrawal

Buprenorphine Injections Effective on Opioid-Associated Euphoria and Withdrawal

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Once-weekly subcutaneous buprenorphine injections block the euphoric effects of opioids and suppress opioid withdrawal in patients with opioid use disorder.

Features of Patients With Chronic Migraine and Frequent Medication Overuse Relapse

Features of Patients With Chronic Migraine and Frequent Medication Overuse Relapse

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In patients with chronic migraine and medication overuse, patients who frequently relapse into overuse following withdrawal have a worse clinical and psychological profile than patients who relapse less frequently.

Methadone: Best Practices for Weaning Pediatric Patients

Methadone: Best Practices for Weaning Pediatric Patients

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Practices pertaining to the use of methadone to facilitate opioid weaning in pediatric patients are widely heterogeneous.

Naltrexone vs Buprenorphine to Treat Opioid Dependence

Naltrexone vs Buprenorphine to Treat Opioid Dependence

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An 8-day detoxification process using low-dose oral naltrexone showed superior efficacy to the standard 15-day approach that uses an agonist taper leading to induction with extended-release naltrexone

Buprenorphine Superior to Methadone in Treating Neonatal Abstinence Syndrome, Study Shows

Buprenorphine Superior to Methadone in Treating Neonatal Abstinence Syndrome, Study Shows

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In babies born in withdrawal from drugs their mothers have taken, buprenorphine may be more effective than methadone at reducing duration of treatment and length of hospital stay.

Buprenorphine Buccal Film Effectively Reduces Full Opioid Agonist Dosage Without Tapering

Buprenorphine Buccal Film Effectively Reduces Full Opioid Agonist Dosage Without Tapering

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No increased risk for opioid withdrawal observed among patients on full mu-opioid agonist therapy who were switched to a buprenorphine buccal film without tapering.

Naloxone Capsule Safe for Opioid-Induced Constipation, Study Notes

Naloxone Capsule Safe for Opioid-Induced Constipation, Study Notes

Sustained release formula efficacious, with no indication of opioid withdrawal or increase in pain.

Electrical Acupoint Stimulation May Ease Withdrawl Pain

Electrical Acupoint Stimulation May Ease Withdrawl Pain

TEAS treatment for 10 days alleviates withdrawal syndrome, cuts rescue opioid requirement.

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