Drug Name:
Tetracycline Rx
Generic Name and Formulations:
Tetracycline HCl 250mg, 500mg; caps.
Company:
Various generic manufacturers
Therapeutic Use:
Indications for Tetracycline:
Adjunct in severe acne.
Adult:
Take with fluids, 1 hour before or 2 hours after meals. Initially 1g daily in 2–4 divided doses. After improvement: 125–500mg daily.
Children:
Not recommended.
Warnings/Precautions:
Renal impairment. Monitor blood, renal and hepatic function in long-term use. Avoid sun and UV light. Discontinue if skin erythema occurs. Pregnancy (Cat.D), nursing mothers: not recommended.
Pharmacological Class:
Tetracycline antibiotic.
Interactions:
Avoid methoxyflurane, photosensitizing agents. May antagonize bactericidal antibiotics; avoid. Reduced absorption with antacids, iron, zinc, calcium, magnesium, dairy products, urinary alkalinizers, other multivalent cations. May reduce effectiveness of oral contraceptives. Monitor prothrombin time with oral anticoagulants.
Adverse Reactions:
Photosensitivity, GI upset, rash, blood dyscrasias, increased BUN, hepatotoxicity; rare: esophagitis and esophageal ulceration.
Note:
Formerly known under the brand names Achromycin V, Tetracyn, Tetrex.
How Supplied:
Contact supplier.
Indications for Tetracycline:
Tetracycline-sensitive infections, including respiratory, genitourinary, skin and soft tissue, and those caused by rickettsiae and Mycoplasma pneumoniae; also cholera, psittacosis, plague, shigellosis.
Adult:
Take with fluids, 1 hour before or 2 hours after meals. 250–500mg 4 times daily.
Children:
<8yrs: not recommended. Take with fluids, 1 hour before or 2 hours after meals. ≥8yrs: 25–50mg/kg/day in 4 divided doses.
Warnings/Precautions:
Renal impairment. Monitor blood, renal and hepatic function in long-term use. Avoid sun and UV light. Discontinue if skin erythema occurs. Pregnancy (Cat.D), nursing mothers: not recommended.
Pharmacological Class:
Tetracycline antibiotic.
Interactions:
Avoid methoxyflurane, photosensitizing agents. May antagonize bactericidal antibiotics; avoid. Reduced absorption with antacids, iron, zinc, calcium, magnesium, dairy products, urinary alkalinizers, other multivalent cations. May reduce effectiveness of oral contraceptives. Monitor prothrombin time with oral anticoagulants.
Adverse Reactions:
Photosensitivity, GI upset, rash, blood dyscrasias, increased BUN, hepatotoxicity; rare: esophagitis and esophageal ulceration.
Note:
Formerly known under the brand names Achromycin V, Tetracyn, Tetrex.
How Supplied:
Contact supplier.
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