IV Tramadol Effective in Second Phase 3 Postoperative Pain Trial
Results of the study showed that compared with placebo, patients treated with IV tramadol 50mg had a statistically superior improvement in pain relief as measured by SPID24.
Surgery
Implementing Surgical Safety Checklist Reduces Mortality
There has been a significant reduction in surgical mortality during the last decade in Scotland that is partially attributable to the implementation of the World Health Organization Surgical Safety Checklist.
Oral Acetaminophen Superior to IV Acetaminophen for Reducing Opioid Use After THA, TKA
Intravenous administration of acetaminophen (APAP) may be less effective than oral administration of APAP for reducing opioid use after total hip or knee arthroplasty.
Intraoperative Lidocaine May Reduce Breast Cancer Surgery-Associated Neuropathic Pain
Large studies examining the efficacy of intraoperative lidocaine infusions on breast cancer surgery-associated pain were found to be feasible.
Predictors of Poor Pain Control Following Surgery
Investigators conducted a meta-analysis to identify predictors of poor postoperative pain control with a goal of developing personalized care pathways to improve outcomes.
Persistent, Prolonged Opioid Use Prevalent After Plastic and Reconstructive Surgery
A significant percentage of patients who undergo plastic and reconstructive surgery have persistent or prolonged opioid use.
Preoperative Long-Acting Opioid Use May Affect Length of Hospital Stay, Readmission Rates
Preoperative long-acting opioid use was found to be associated with longer lengths of hospital stay and increased all-cause and pain-related readmission in patients undergoing inpatient and ambulatory surgeries, respectively.
Predicting Time to Pain Resolution, Recovery, and Opioid Cessation After Surgery
In surgical patients, time to pain resolution, complete recovery from surgery, and opioid cessation were found to be predicted by the worst pain occurring 10 days after surgery.
Persistent Postsurgical Opioid Use in Youth Associated With Long-Term Use of Opioids by Relatives
Persistent opioid use in opioid-naive adolescents and young adults undergoing surgery or dental procedures may be associated with long-term use of opioids by a relative.
Lancet Article Series on Postoperative Pain Management Practices
A series of 3 articles published in the Lancet is dedicated to highlighting the nature of current postsurgical pain management practices, including the use of peri- and postoperative opioids, that are thought to play a part in driving the opioid crisis.
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