Review Explores Risk for Early-Onset Stroke, Parkinson Disease With Methamphetamine Use
The review authors sought to elucidate the neurological harms of methamphetamine, which are well-documented but poorly understood.
Substance Use
JACC Review Highlights Cardiovascular Outcomes Associated With Acute and Chronic Opioid Use
This review explores the cardiovascular consequences of opioids and the contributions of off-target electrophysiologic properties to mortality, and provides practical safety recommendations.
Who Is Treated for Substance Use Disorder During the Postpartum Period?
The researchers studied mothers of infants with neonatal abstinence syndrome and/or prenatal substance exposure and whether they received treatment for substance use disorder.
Alcohol Withdrawal: Individualized Care and Pharmacologic Treatment
More than 50% of patients with alcohol use disorder develop alcohol withdrawal symptoms within hours of discontinuing or decreasing alcohol use.
Medication for Opioid Abuse Linked to Better HIV Viral Suppression, ART Adherence
Researchers attempted to determine if medications for opioid use disorder integrated with infectious disease measures can lead to better infectious disease outcomes.
Substance Misuse Among Gender Minority Adolescents Associated with Marginalization
Study data published in PLoS One suggest that gender minority (GM) adolescents may engage in substance use more frequently than their peers.
US Overdose-Related Cardiac Arrests Reached Unprecedented Highs During the COVID-19 Pandemic
With overdose deaths spiking during the early months of the COVID-19 pandemic, data was not disaggregated by month, race/ethnicity, or other social attributes. The study investigators utilized data from emergency medical services in racial/ethnic, social, and geographic trends in overdose-related cardiac arrests.
National Effort to Identify the “Top 5 Emerging Practices to Prevent Substance Misuse”
With drug use rising, society requires new prevention approaches. The not-for-profit Center for US Policy (CUSP) announced a national contest to identify the “Top 5 Emerging Practices to Prevent Substance Misuse.”
FDA Accepts Resubmitted Zimhi NDA for Opioid Overdose Treatment
The FDA has accepted for review the resubmitted NDA for Zimhi, a high-dose naloxone injection product candidate for the treatment of opioid overdose.
Buprenorphine Treatment Activity Varies Widely Among Clinicians
There is large variation in buprenorphine prescribing, with a small percentage of clinicians accounting for most buprenorphine treatment in the United States.
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