Pain Archives - Clinical Pain Advisor

Migraine & Headache

Combination Treatment Appears Beneficial for Chronic Migraine

By

Cassandra Pardini, PharmD

May 6, 2021

Data analysis revealed that CGRP mAbs were discontinued more frequently than onabotulinumtoxinA (23% vs 3%).

Opioid Addiction

High Fluidity of Opioid Use Behaviors Among Adults With Chronic Noncancer Pain

By

Jessica Nye, PhD

May 4, 2021

While there are concerns about long-term prescribed opioid use among individuals with chronic noncancer pain, until now there hasn’t been a study which investigated whether the same patients engage in a risky pattern of use in the long term.

Neuropathic Pain

Cross-Sectional Area Reference Values for Peripheral Nerve Ultrasounds

By

Brandon May

April 27, 2021

To help standardize peripheral nerve ultrasound protocols, study investigators pooled reference cross-sectional area values of lower extremity nerves.

PRP platelet rich plasma scalp injection

General Pain

Ice Pack Compression, Vibration Anesthesia Device Reduce Pain During Scalp Injections

By

Colby Stong

April 23, 2021

Inexpensive, practical, and safe strategies to reduce patients’ pain level during inactivated PRP scalp injections are reviewed.

General Pain

Case Report: Pain Med Dose Linked to Patient’s Sleepwalking

By

Cassandra Pardini, PharmD

April 16, 2021

The patient, who had suffered a traumatic brain injury approximately 8 months prior, presented to the emergency department complaining of increasing dizziness as well as sleepwalking frequency.

No single treatment for HS is effective in eradicating disease or preventing progression, but early recognition and treatment are critical to preventing further progression to severe disease that can have an impact on quality of life.8 Therapeutic goals for stage 1 HS in young patients are to reduce pain and inflammation and prevent scarring and disease progression through multimodal management. Topical disinfectants are generally considered ineffective.4 Topical antibiotics are the therapy of choice for mild-to-moderate disease, with the introduction of oral antibiotics where topical formulations are inadequate.4 Once the disease has progressed, biologic disease modifying antirheumatic therapies, laser therapy, and surgery may have some benefit.8 Evidence supporting the use of intravenous infliximab in Hurley stage 2 and 3 HS has not been adequate enough to recommend it.9 Treatment of HS requires an aggressive multidisciplinary effort that involves antibiotic treatment, multimodal anti-inflammatory therapy and hormonal therapies, dietary and lifestyle modifications, and avoidance of physical trauma to the affected regions, which can lead to rupture of abscesses, along with early surgical unroofing and debridement. Additionally, because of the stigma and psychological distress, counseling for possible depression and to support coping skills is also recommended.3

General Pain

Evidence-Based Comorbidity Screening for Patients With Hidradenitis Suppurativa

By

Brandon May

April 1, 2021

To improve long-term outcomes for patients with HS, evidence-based screening recommendations to help clinicians recognize and treat 30 comorbid conditions have been developed.

Neuropathic Pain

Changes in B12, MMA, and Homocysteine Linked to Peripheral Neuropathy

By

Jessica Nye, PhD

March 31, 2021

The researchers investigated how low levels of B vitamins were associated with peripheral neuropathy and the effect of vitamin treatment on symptoms of pain.

Migraine & Headache

Oral Celecoxib Solution May Provide Short-Term Pain Relief for Migraine

By

Brandon May

March 24, 2021

Liquid solution celecoxib may offer headache relief and improvements in functional disability in patients with migraine.

Musculoskeletal Pain

Fibromyalgia Linked to Hypersensitivity to Heat and Auditory Stimuli

By

Brandon May

March 19, 2021

The researchers’ hypothesis is that supraspinal augmentation of sensory input, including sound, may represent a hallmark of fibromyalgia.

Opioid Addiction

Fear Avoidance Beliefs and Behaviors Contribute to Unsuccessful Opioid Cessation in CNCP

By

Brandon May

March 17, 2021

The objective of this study was to describe differences between patients with chronic noncancer pain who could stop using chronic opioid analgesic therapy and those who exhibited refractory COAT reliance.