Florida’s Restrictive Opioid Law HB21 Did Not Lead to Increased NSAID Prescriptions
The researchers evaluated how an opioid restriction law in Florida affected the use of prescription NSAIDs.
Nonsteroidal Anti-Inflammatory Drugs
Bupivacaine and Meloxicam Now Available for Postsurgical Analgesia for Up to 72 Hours
Zynrelef is a dual-acting local anesthetic that delivers a fixed-dose combination of bupivacaine, an amide local anesthetic, and meloxicam, an NSAID.
Single Injection of Ketorolac Reduces Surgical Pain More Effectively Than Opioids
The researchers’ goals were to compare the efficacy and adverse effects of single‐dose intravenous ketorolac for postoperative pain in adults and compare it with placebo or an active comparator.
Study: Ibuprofen Found Safest NSAID for the Kidney
In a study comparing the effect of 9 oral nonsteroidal anti-inflammatory drugs on kidney function, ibuprofen conferred the lowest risk for incident eGFR less than 60 mL/min/1.73 m2 and an eGFR decline of 30% or greater.
NSAID Use Not Linked to Increased Mortality, Severity in COVID-19
Nonsteroidal anti-inflammatory drug (NSAID) use is not associated with increased mortality or severity of COVID-19.
Return ED Visit Rates With Opioid vs Nonopioid Low Back Pain Treatments Evaluated
This study compares the use of opioids vs nonopioids in the emergency department for patients with low back pain and the proportion of patients who return within 30 days.
NSAID May Increase AKI Risk in Hospitalized Children
Avoiding inappropriate use and overdosing of drugs with nephrotoxic effects is an important strategy to prevent hospital-acquired AKI in children, according to investigators.
FDA: NSAID Use Should Be Avoided in Pregnancy Even Sooner Than 30 Weeks
The use of NSAIDs after 20 weeks of pregnancy may lead to low levels of amniotic fluid surrounding the baby resulting in kidney complications.
Antidepressant, NSAID Identified as Culprits in SIADH Case
The patient noted that she was initiated on naproxen by her primary care physician 2 weeks prior to her presentation.
Analgesic Ceiling Dose of Ibuprofen for Acute Pain in the ED Determined
Ibuprofen doses of 400, 600, and 800 mg were found to provide comparable analgesia in adult patients seen in the emergency department with moderate to severe acute pain.
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