Novel 12-LOX Inhibitor Fast Tracked for Heparin-Induced Thrombocytopenia
VLX-1005 is a first-in-class, selective small molecule inhibitor of 12-lipoxygenase, a key target within the arachidonic acid pathway.
Interventional Pain Management
Research Needed to Understand Effects of Low-Dose Radiation
Multidisciplinary research is needed to improve understanding of the impact of low doses of radiation on human health.
Postoperative Anxiety During Care Transitions Reduced With Peer Mentoring
Mentoring programs can help improve patients’ transition from hospital to home by reducing their postoperative anxiety following a transplant.
Interactive, Nonpharmacologic Interventions May Improve Pain Management in Dementia
In a systematic literature review, researchers sought to identify, summarize, and compare data on nonpharmacologic interventions for pain management among patients with dementia and assess their effectiveness.
Mirror Therapy Reduces Phantom Limb Pain in Individuals With Amputations
In a systematic review and meta-analysis, study authors evaluated available evidence to determine the effect of mirror therapy on short- and long-term phantom limb pain in individuals with amputations.
Preoperative Epidural Analgesia Decreases Cardiac Events, Mortality Risk Among Patients With Hip Fracture
The researchers’ goal was to determine the efficacy and safety of presurgical epidural analgesia for hip fracture patients undergoing surgical repair.
Exercise and Manual Therapy Modulate Pressure Pain Thresholds for Patients With Shoulder Pain
This systematic review and meta-analysis analyzes whether interventions for patients with shoulder pain can modify quantitative sensory testing parameters.
Spine Intervention Society Publishes Recommendations on Corticosteroid Timing and COVID-19 Vaccine Efficacy
The Spine Intervention Society sets out to separate myths from facts about the effect of corticosteroid injections on the efficacy of vaccines for COVID-19.
Peripheral Nerve Stimulation Reduced Pain, Opioid Use After Ambulatory Orthopedic Surgery
Prior to surgery, patients had a percutaneous lead inserted in the brachial plexus, femoral, or sciatic nerve using ultrasound guidance.
Peripheral Nerve Block Controls Pain Better Than Spinal Anesthesia After Ankle Surgery
This study assessed the postoperative pain profile of peripheral nerve block anesthesia, which is increasingly popular for acute ankle fracture surgery, as compared to spinal anesthesia.
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