The 7-item Migraine-Specific Quality of Life Questionnaire version 2.1 electronic patient-reported outcome Role Function-Restrictive domain was found to represent a reliable and valid tool for assessing the functional impact in participants of clinical trials of episodic and chronic migraine.
Pregnant women are considered a “vulnerable” population in the eyes of clinical researchers.
In a retrospective analysis, investigators assessed the effects of topical trigger point treatments on headache symptoms in patients with migraine.
Research findings suggest the need for greater adherence to a standardized set of policies aimed at improving transparency among clinical trial funders.
The FDA Digital Health Software Precertification Program represents a feasible solution to regulate software classified as a medical device.
Many translational barriers exist between preclinical research and clinical practice.
Key factors susceptible to improve the design of clinical trials on analgesics for acute pain in pediatric populations were reviewed and recommendations published.
The benefits associated with medical cannabis therapy may be overestimated due to inadequate blinding in clinical trials.
The need for data transparency carries an ethical and moral obligation and requires nonselective and unbiased publication of clinical results.
In a controversial and divisive article, a group of researchers proposes to improve “statistical standards of evidence” by lowering the P value from P <.05 to P <.005 in the fields of biomedical and social sciences.
