Computational modeling based on hypothalamic-pituitary-adrenal axis activity history may allow to shed light on the mechanisms of pain and the transition from acute low back pain to chronic pain.
Patients with chronic low back pain and comorbid fibromyalgia may have central sensitization and psychosocial symptoms.
Investigators assessed the effectiveness of lumbar transforaminal steroid injection to treat radicular pain in patients with disk herniation.
NKTR-181 was found to be a safe, effective, and well tolerated treatment over the long term in patients with moderate to severe chronic low back pain.
Self-administered acupressure may be efficacious for reducing pain and fatigue in patients with chronic low back pain.
Physical therapy informed by Acceptance and Commitment Therapy may reduce short-term but not long-term disability compared with standard treatment in patients with chronic low back pain.
Patients who decreased opioid use while undergoing basivertebral nerve ablation were found to experience greater relief of chronic low back pain than those who increased opioid use.
The use of novel waveforms, frequencies, and stimulation modes in spinal cord stimulation (SCS) therapies may be more effective at relieving chronic low back pain and/or leg pain compared with traditional tonic low-frequency SCS.
Joint hypermobility may not be associated with chronic low back pain or lumbar osteoarthritis.
Older individuals with symptomatic lumbar stenosis who were given lumbar epidural steroid injections were found to have improved pain scores and physical function 1 month after the intervention.
