Intravenous administration of acetaminophen (APAP) may be less effective than oral administration of APAP for reducing opioid use after total hip or knee arthroplasty.
Individuals with knee osteoarthritis who have indicators of high vs low/no levels of neuropathic pain may be at elevated risk for chronic pain after total knee replacement surgery.
The use of liposomal bupivacaine after total knee arthroplasty with a peripheral nerve block may not result in reductions in inpatient intake of opioids, hospital length of stay, or opioid-related complications.
Regional anesthesia is associated with a lower opioid consumption in both knee and hip replacement surgeries, compared to general anesthesia.
Suspecting that this phenomenon might be the source of my nighttime pain, causing significant REM sleep deprivation, I reasoned that a neuromodulator such as a gabapentinoid might be helpful.
Addition of an interspace between the popliteal artery and capsule of the posterior knee block and adductor canal block to periarticular injection is associated with less pain after total knee arthroplasty.
Sciatic nerve block may represent an effective complement to femoral nerve block for total knee arthroplasty.
Multimodal analgesia after hip or knee arthroplasty may be associated with fewer complications and reduced opioid prescriptions and hospital length of stay, compared with unimodal analgesia.
Fewer respiratory, GI issues; reductions also seen in opioid prescriptions and hospital length of stay
In patients with knee osteoarthritis, high pain levels and low pressure pain thresholds at baseline predicted worse pain outcomes after total knee replacement surgery, but did not predict outcomes after nonsurgical interventions.
