Opioid Prescribing Rates Reduced at State Level From 2010 to 2016
Prescription drug monitoring program data from individual states show a decline in opioid prescribing rates in 11 participating states from 2010 to 2016.
Acute Pain
Few Providers Account for Large Number of Opioid Prescriptions
A small proportion of providers account for almost half of all opioid doses and about one-quarter of opioid prescriptions.
Production of Two Excedrin Painkillers Halted
Production and distribution of Excedrin Extra Strength and Excedrin Migraine products have been temporarily stopped.
Drop in Opioid Prescribing at ED Discharge Noted in Recent Years
The percentage of emergency department visits with an opioid prescribed increased from 2006-2007 to 2010-2011 then decreased to 2016-2017.
Ibuprofen Injection Now Available in Ready-to-Use Bags for Pain Relief
A ready-to-use formulation of Caldolor (ibuprofen injection) has been made available by Cumberland Pharmaceuticals.
Decline in Prescribed Opioids Noted From 2014 to 2016 in the United States
From 2014 to 2016, there was a decrease in the proportion of U.S. adults who were prescribed opioids, with a larger decrease seen for those who reported moderate or more severe pain versus less-than-moderate pain.
NASEM Report Provides Framework for Developing Opioid Prescribing Guidelines
In an effort to further address the current opioid crisis, the FDA contracted the NASEM to examine existing opioid prescribing guidelines and to help outline the type of research needed to fill the gaps in evidence.
Early Regional Anesthesia Effective for Extremity Injury Pain
Regional anesthesia may aid pain management if used soon after traumatic injury of the extremities.
FDA: Cases of Respiratory Depression With Gabapentinoids Reported
The FDA is requiring new warnings be added to the prescribing information for gabapentinoids about the risk of respiratory depression. This class of drugs includes gabapentin (Neurontin, Gralise, Horizant) and pregabalin (Lyrica, Lyrica CR).
NDA Submitted for IV Tramadol for Inpatient Pain Management
The application includes data from two phase 3 clinical trials in patients following bunionectomy and abdominoplasty surgeries.
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