AHA Presidential Statement: The Link Between Opioid Use, CVD, and Stroke
The AHA has issued a Presidential Advisory Statement outlining considerations for addressing the effects of opioids on cardiovascular and neurovascular health.
Acute Pain
Inconsistent Evidence to Support the Efficacy, Safety of Muscle Relaxants for Treatment of Low Back Pain
In a systematic review and meta-analysis, Neuroscience Research Australia investigators quantitatively analyzed 31 RCTs with a total of 6505 participants.
Robust Prescription Monitoring Programs Influence Discontinuation of Long-Term Opioid Use Patterns
A Weill Cornell Medicine team analyzed Health Care Cost Institute database claims, with opioid prescription gaps ≥30 days considered long-term nonuse.
Topical Lidocaine Gel Reduces Pain Scores and Opioid Use Consumption After Following Cardiac Surgery
The objective of this systematic review was to study the effects of lidocaine on postoperative pain scores and recovery after cardiac surgery.
Orthopedic Surgery May Not Be More Effective Than Nonsurgical Alternatives
No strong, high-quality evidence shows that many commonly performed elective orthopedic procedures are more effective than nonoperative alternatives.
VR Game Reduces Self-Reported Pain Scores During Burn Dressing Changes Among Children
Researchers sought to determine whether smartphone-based virtual reality (VR) games are effective in reducing pain among pediatric patients in real-world burn clinics.
Bupivacaine and Meloxicam Now Available for Postsurgical Analgesia for Up to 72 Hours
Zynrelef is a dual-acting local anesthetic that delivers a fixed-dose combination of bupivacaine, an amide local anesthetic, and meloxicam, an NSAID.
Migraine Increases Risk of Obstetric Complications
Pregnant women with migraine are at increased risk of having obstetric and medical complications compared to women without migraine.
The 15-Day Threshold Does Not Adequately Distinguish Between Episodic and Chronic Migraines
The researchers’ goal was to evaluate whether the 15-day threshold of headache days per month reflects significant differences in disability across the migraine and its spectrum.
Genetic, Ethnicity-Dependent Factors Predict Variability in Acute Postoperative Patient-Controlled Analgesia
Genetic and nongenetic factors should be evaluated when examining factors contributing to variability in acute postoperative opioid use.
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