Four-to-Seven-Day Opioid Prescription Likely Sufficient for Acute Pain Treatment
An opioid supply for seven or fewer days might be sufficient for most patients seen in primary care settings for acute pain who appear to need opioid analgesics.
Acute Pain
Authorized Generic of Flector Patch Now Available From Teva
An authorized generic of Flector Patch (diclofenac epolamine topical patch) has been made available by Teva Pharmaceuticals for the topical treatment of acute pain due to minor strains, sprains, and contusions.
New Drug Combination May Be An Effective Prophylactic for Opioid-Induced Nausea
CL-108, a new combination of a low-dose antiemetic with hydrocodone and acetaminophen, may be a safe and effective prophylactic medication for the treatment of opioid-induced nausea and vomiting in individuals treated for moderate to severe acute pain.
Methylprednisolone May Provide Short-Term Relief From Acute Diskogenic Sciatica
Intravenous administration of methylprednisolone may be associated with short-term pain relief in patients with acute diskogenic sciatica.
Ketamine Noninferior to Fentanyl for Traumatic Injury Pain in Children
Intranasal ketamine was found to be noninferior to intranasal fentanyl for providing analgesia in children presenting to the emergency department with acute injuries of the extremities.
Use of Neuraxial Analgesia Varies by State
Use of neuraxial analgesia for labor varies across US states, but the causes underlying those variations are unclear.
Sufentanil Sublingual Tablet Well-Tolerated, According to Pooled Safety Data
The pooled analysis (N=804) evaluated clinical studies of sufentanil sublingual tablet (SST) at 30mcg dose equivalents over ≤72 hours for moderate-to-severe acute pain management in both postoperative and emergency room patients.
FDA Approves Two New Strengths of Apadaz for Pain Management
Apadaz was initially approved in February 2018 as 6.12mg/325mg immediate-release tablets for the short-term (no more than 14 days) management of acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.
Postpartum Pain Associated With Increased Risk for Postpartum Depression
Patients at high risk for postpartum depression may need denser analgesia control after delivery.
Women Fed Soy Formula as Infants More Likely to Experience Menstrual Pain
Researchers at the National Institute of Environmental Health Sciences (NIEHS), Vanderbilt University Medical Center, and the Henry Ford Health System analyzed patient data from African-American women aged 23 to 35 years (N=1553) who were participating in the NIEHS Study of Environment, Lifestyle, and Fibroids (SELF).
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