Generic Name and Formulations:
Sodium sulfate 17.5g, potassium sulfate 3.13g, magnesium sulfate 1.6g; per 6oz of soln.
Braintree Laboratories, Inc.
Indications for SUPREP:
Bowel cleansing before colonoscopy.
Start the evening before colonoscopy: dilute 1 bottle to 16oz with water and drink entire amount. Drink 32oz of water over the next hour. Next morning: repeat using the second bottle. Complete prep at least 2hrs before colonoscopy.
GI obstruction or perforation. Gastric retention. Toxic colitis. Toxic megacolon. Ileus.
Maintain adequate hydration. Correct electrolyte abnormalities before use. Renal impairment; monitor baseline and post-colonoscopy electrolytes, creatinine, BUN. History of QT prolongation, uncontrolled arrhythmias, recent MI, unstable angina, CHF, or cardiomyopathy: increased risk of arrhythmias; consider ECGs at pre-dose and post-colonoscopy. Gout. Seizure. Inflammatory bowel disease. Severe ulcerative colitis. Impaired gag reflex. Risk of regurgitation or aspiration. Pregnancy (Cat.C). Nursing mothers.
Concomitant diuretics, ACE inhibitors, ARBs, NSAIDs; may affect renal function. Drugs that may lower the seizure threshold (eg, tricyclic antidepressants), alcohol or benzodiazepine withdrawal, known or suspected hyponatremia: may increase risk of seizures. Caution with drugs that may increase risk of electrolyte abnormalities, arrhythmias or QT prolongation. Drugs administered within 1 hour of start of Suprep may not be absorbed.
Overall discomfort, abdominal distention and pain, nausea, vomiting; transient elevated uric acid, mucosal ulcerations and ischemic colitis.
Bowel prep kit—1 (2 x 6oz bottles of soln w. mixing container)
Clinical Pain Advisor Articles
- Manual Therapy vs Opioids for Management of Shoulder, Spine Pain
- Opioids: Clinician Concern and Prescribing Practices
- Screening for Hyperglycemia Prior to Steroid Injections for Chronic Pain
- Ensuring Safety During Long-Term Opioid Therapy
- Intervention by Pharmacists May Effectively Reduce Use of Inappropriate Medications in the Elderly
- Serum Vitamin D Levels and Risk for Migraine
- Rimegepant Orally Dissolving Formulation Provides Rapid Relief From Acute Migraine
- Updated Evidence-Based Recommendations for Buprenorphine Treatment
- Business Degree Increasingly Useful for Doctors
- PainDETECT May Not Be Optimal to Detect Neuropathic Components of Orofacial Pain
- Kinesiophobia May Be Associated With Greater Cutaneous Allodynia in Migraine
- CDC: 8.8% of Individuals in the United States Uninsured in First Half of 2018
- Patient Experiences Shed Light on Diagnostic Errors
- Topical Migraine Trigger Point Treatment as Effective as Injection
- Wikipedia in Medical Education: An Educator's Guide to Crowdsourcing