SULFAMYLON 5% TOPICAL SOLUTION Rx
Generic Name and Formulations:
Mafenide acetate 50g/packet; pwd for reconstitution (5% soln after mixing).
Indications for SULFAMYLON 5% TOPICAL SOLUTION:
Adjunct to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds.
Adults and Children:
<3months: not recommended. ≥3months: Cover grafted area with one layer of fine mesh gauze. Cut an eight-ply burn dressing to the size of graft, wet with solution using an irrigation syringe and/or tubing until noticeable leaking. Maintain moisture with irrigation tubing (see literature) or wet dressing every 6–8 hours as needed. May leave wound dressings undisturbed for up to 5 days, except when irrigating. Additional soaks may be initiated until graft take is complete. Continue treatment until autograft vascularization and healing is progressing (approx. 5 days). Individual grafting procedure: max 5 days. Withhold therapy for 24–48 hours if acidosis occurs.
G6PD deficiency. Sulfite sensitivity. Asthma. Acute renal failure. Monitor acid-base balance closely (esp. with extensive 2nd degree or partial thickness burns, pulmonary or renal impairment). Pregnancy (Cat.C); (crm: not recommended for women of childbearing potential; unless burn area >20% of total body surface). Nursing mothers: not recommended.
Application-site pain, burning sensation, allergic manifestations (eg, rash, pruritus, facial edema, swelling, erythema; discontinue if occur), tachypnea, hyperventilation, metabolic acidosis; respiratory alkalosis, fatal hemolytic anemia with disseminated intravascular coagulation, fungal colonization; rare: excoriation of new skin, bleeding of skin.
Crm—2oz, 4oz, 16oz
Clinical Pain Advisor Articles
- Notifications by PDMPs May Not Effectively Reduce Opioid Misuse
- Virtual Reality May Effectively Reduce Sensory, Affective, and Cognitive Pain During Labor
- Suprazygomatic Sphenopalatine Ganglion Block May Quickly Relieve Status Migrainosus Pain
- Electroacupuncture May Help Reduce Opioid Use in Chronic Musculoskeletal Pain
- Low Literacy Self-Management Program for Chronic Pain May Be Effective
- Neuropathic Pain Medications
- Higher Buprenorphine Dose May Not Increase Severity of Neonatal Abstinence Syndrome
- Terms Used for Addiction May Be Associated With Explicit, Implicit Bias
- Ketamine Infusions May Be Effective for Refractory Headache
- Physical, Psychosocial Activity May Be Protective Against Development of Chronic Pain in Older Adults
- The Challenge of Compassion in Modern Healthcare Settings
- Republican Opposition to Obamacare: What's Done, What's to Come
- Lowering Default Pill Counts in EMRs May Effectively Reduce Postoperative Opioid Prescription Numbers
- Steps Taken to Increase Use of Electronic Tools in Medicine
- Daily and Retrospective Pain Measurements Comparable in Hip Osteoarthritis