Substance Use

FDA Warns Two Companies About Bogus Opioid Addiction Treatment

FDA Warns Two Companies About Bogus Opioid Addiction Treatment

Warning letters about products illegally marketed as treatments for opioid addiction, pain, and anxiety have been sent to two companies from the FDA.

Opioids: Clinician Concern and Prescribing Practices

Opioids: Clinician Concern and Prescribing Practices

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Clinicians who are highly concerned about opioid misuse, addiction, and psychological dependence may be more confident but also more reluctant to prescribe opioids.

Drug Overdose Mortality Rates Rising in the United States

Drug Overdose Mortality Rates Rising in the United States

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Drug overdose mortality rates are on the rise in several countries, particularly in the United States.

Risk Factors Identified for Suicidal Ideation in Substance Use Disorders

Risk Factors Identified for Suicidal Ideation in Substance Use Disorders

A new study examines a link between first-onset suicidal ideation and substance use disorders.

Association Between Opioid and Benzodiazepine Misuse and Suicidal Ideation

Association Between Opioid and Benzodiazepine Misuse and Suicidal Ideation

Investigators sought to determine whether opioid and benzodiazepine use and misuse were associated with past-year suicidal ideation in older adults in the United States.

Additional Measures Needed for a Comprehensive Public Health Approach to the Opioid Crisis

Additional Measures Needed for a Comprehensive Public Health Approach to the Opioid Crisis

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In an effort to address the ongoing opioid crisis adequately, a set of measures complementing the current efforts at state and federal levels would need to be implemented for a more "coordinated and comprehensive approach" to the issue.

Quantity of Opioids Prescribed Postop Linked to Consumption

Quantity of Opioids Prescribed Postop Linked to Consumption

The quantity of opioids prescribed after surgery is associated with patient-reported opioid consumption.

Opioid Misuse Varies With Sexual Orientation

Opioid Misuse Varies With Sexual Orientation

Opioid misuse varies with sexual orientation, with increased misuse among female bisexuals.

Pain Management Telementoring May Cut Opioid Prescribing

Pain Management Telementoring May Cut Opioid Prescribing

Military patients whose primary care clinicians participated in a telementoring program, including education on pain management best practices, have larger declines in opioid-related prescriptions than patients whose clinicians did not participate.

Examining the Effect of State Laws Restricting Access to Methadone on Overdose Death Rates

Examining the Effect of State Laws Restricting Access to Methadone on Overdose Death Rates

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The law restricting access to medication-assisted treatment with methadone to opioid treatment programs may have contributed to reducing opioid-related overdose death rates in the United States.

FDA Cracks Down on Companies Selling Dietary Supplements Containing Tianeptine

FDA Cracks Down on Companies Selling Dietary Supplements Containing Tianeptine

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While approved in Europe, Asia and Latin America, tianeptine is an unscheduled pharmaceutical agent in the US that has been linked to serious adverse events, including death, when used for recreational purposes.

Naloxone Products Stay Effective Long After Expiration Date

Naloxone Products Stay Effective Long After Expiration Date

Two naloxone products used to treat opioid overdose patients remain chemically stable long after their expiration dates.

Updated Evidence-Based Recommendations for Buprenorphine Treatment

Updated Evidence-Based Recommendations for Buprenorphine Treatment

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Seven key practice areas for the use of buprenorphine for the treatment of opioid use disorders were updated with new evidence-based recommendations.

Rapid Fentanyl Test Strips Accepted by Young Adult Drug Users

Rapid Fentanyl Test Strips Accepted by Young Adult Drug Users

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For young people who use drugs, rapid fentanyl test strips may represent an acceptable way to detect illicitly manufactured fentanyl.

Moral Hazard vs Morality Approaches in the Opioid Crisis

Moral Hazard vs Morality Approaches in the Opioid Crisis

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Economists argue that because naloxone prevents overdoses, it also nudges users toward riskier behaviors. Physicians disagree.

FDA Panel Votes in Favor of Abuse-Deterrent Oxycodone Reformulation

FDA Panel Votes in Favor of Abuse-Deterrent Oxycodone Reformulation

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The vote was taken in a joint meeting of the Anesthetic and Analgesic Drug Products Advisory Committee and Drug Safety and Risk Management Advisory Committee.

Patterns of Non-Medical Prescription Opioid Use in Adolescents

Patterns of Non-Medical Prescription Opioid Use in Adolescents

The majority of adolescents taking prescription opioids for non-medical purposes were found to get these drugs from someone else.

Half of the Responders to Our Poll Agree With the Approval of Dsuvia: We Want to Hear From You

Half of the Responders to Our Poll Agree With the Approval of Dsuvia: We Want to Hear From You

Clinical Pain Advisor is seeking feedback on the FDA approval of Dsuvia for the management of acute pain.

Tools to Address the Opioid Crisis

Tools to Address the Opioid Crisis

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The Stopping the Transmission of Opioids to the Next Generation tool allows clinicians treating women of childbearing age with opioid use disorder to estimate risks associated with pregnancies in this patient population.

Methamphetamine Use on the Rise in Patients With Opioid Use Disorder

Methamphetamine Use on the Rise in Patients With Opioid Use Disorder

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The rate of past-month methamphetamine use was found to have significantly risen in individuals with opioid use disorder from 2011 to 2017.

Opioid Use May Be Associated With Difficulty Falling Asleep in Adults With Mild Chronic Pain

Opioid Use May Be Associated With Difficulty Falling Asleep in Adults With Mild Chronic Pain

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Opioid use may be associated with more difficulty falling asleep in adults with low-intensity chronic pain.

Opioid Use Often Persists in Workers' Compensation Claimants

Opioid Use Often Persists in Workers' Compensation Claimants

Many patients in a workers' compensation cohort have persistent opioid use.

Dsuvia Gains FDA Approval: We Want to Hear Your Thoughts

Dsuvia Gains FDA Approval: We Want to Hear Your Thoughts

Clinical Pain Advisor is seeking feedback on the FDA approval of Dsuvia for the management of acute pain.

Nonopioid Lofexidine Safe and Effective for Managing Opioid Withdrawal Syndrome

Nonopioid Lofexidine Safe and Effective for Managing Opioid Withdrawal Syndrome

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Lofexidine may expand the treatment options available for managing withdrawal when buprenorphine and methadone are unavailable or undesirable.

Bill to Fight U.S. Opioid Crisis Signed Into Law

Bill to Fight U.S. Opioid Crisis Signed Into Law

A bipartisan bill meant to combat the United States' opioid abuse epidemic was signed into law Oct. 24 by President Donald Trump.

Suboptimal Management of Patients Hospitalized for Injection Drug Use-Related Infections

Suboptimal Management of Patients Hospitalized for Injection Drug Use-Related Infections

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Patients admitted to the hospital with an infection related to injection drug use were found to rarely be prescribed medication-assisted treatment, but instead were screened, received a brief intervention and a referral to treatment.

The Unintended Consequences of the CDC Opioid Guideline According to Pain Management Specialists

The Unintended Consequences of the CDC Opioid Guideline According to Pain Management Specialists

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The guideline formulated by the Centers for Disease Control and Prevention in an effort to curb opioid overdose-related deaths included a recommendation for steep reductions in opioid doses for patients taking high doses of the drug for chronic pain.

Risk of Opioid-Benzodiazepine Overlap Up for Dual Prescribing

Risk of Opioid-Benzodiazepine Overlap Up for Dual Prescribing

Receiving prescriptions from both the U.S. Department of Veterans Affairs (VA) and Medicare Part D is associated with increased risk for overlapping of opioid and benzodiazepine prescriptions.

Red Cross Releases Online Course on How to Respond to an Opioid Overdose

Red Cross Releases Online Course on How to Respond to an Opioid Overdose

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The training has information on how to use several products including a nasal atomizer, Narcan Nasal Spray and Evzio.

Set of Interventions May Effectively Reduce Opioid Overprescribing

Set of Interventions May Effectively Reduce Opioid Overprescribing

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Interventions combining prescriber and patient education, a reduction in default amounts on opioid prescription orders, and increased oversight and accountability of individual prescribers may represent effective strategies for reducing opioid overprescribing.

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