A 23-year-old woman presents with a recurrence of severe, crampy abdominal pain and a prolonged history of diarrhea. Her chart shows previous complaints of fatigue and joint pain, as well as evidence of weight loss during the past 2 years. Examination reveals aphthous oral ulcers and right lower quadrant abdominal tenderness. An endoscopy later demonstrates focal ulcerations adjacent to normal tissue in the small bowel, producing a cobblestone appearance. Learn more about this case, take the quiz, and join the conversation on Figure 1.
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