The treatment combines buprenorphine, a partial-opioid agonist, with naloxone, an opioid antagonist.
Researchers examined the extent to which pharmaceutical industry marketing of opioid products to physicians during 2014 correlated with opioid prescribing in 2015.
At a Glance Overdose from opioids can occur after ingestion of natural products, such as morphine and codeine, or after ingestion of semi-synthetic or synthetic opioids, such as heroin, oxycodone, hydrocodone, hydromorphone, fentanyl, methadone, or meperidine. Heroin is a commonly abused semi-synthetic opioid with no medical use. Although other opioids can be prescribed for therapeutic…
Persistent opioid use in opioid-naive adolescents and young adults undergoing surgery or dental procedures may be associated with long-term use of opioids by a relative.
A prior authorization policy for extended-release/long-acting opioids may help reduce the number of opioid-naive patients who initiate extended-release/long-acting opioid use but may also increase the rate of short-acting opioid prescriptions.
Concurrent benzodiazepine and opioid use increased by 80% between 2001 and 2013 in the United States and significantly contributes to the overall population risk of opioid overdose.
Adolescents with anxiety, mood, neurodevelopmental, sleep, and nonopioid substance use disorders and most mental health treatments were significantly more likely to receive opioids.
The guideline formulated by the Centers for Disease Control and Prevention in an effort to curb opioid overdose-related deaths included a recommendation for steep reductions in opioid doses for patients taking high doses of the drug for chronic pain.
This study provides evidence to explain activation of peripheral opioid receptors by inflammation.
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New data suggests a decline in emergency room opioid prescribing rates.