Sciatica

Methylprednisolone May Provide Short-Term Relief From Acute Diskogenic Sciatica

Methylprednisolone May Provide Short-Term Relief From Acute Diskogenic Sciatica

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Intravenous administration of methylprednisolone may be associated with short-term pain relief in patients with acute diskogenic sciatica.

Limited Benefits of TNF-α Inhibitors for Chronic Low Back Pain

Limited Benefits of TNF-α Inhibitors for Chronic Low Back Pain

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Anticytokine treatments may be ineffective in alleviating chronic low back pain with or without sciatica.

Combination Therapies for Low Back Pain, Sciatica May Not Have Added Benefit

Combination Therapies for Low Back Pain, Sciatica May Not Have Added Benefit

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There is a lack of evidence supporting the benefits of combination drug therapy over monotherapy for the management of low back pain and sciatica.

Various Factors Affect Progress in Back-Related Leg Pain, Sciatica

Various Factors Affect Progress in Back-Related Leg Pain, Sciatica

Belief in a long recovery, many symptoms attributed to pain negatively tied to improvement/

Incidence of Musculoskeletal Disorders, Depression in Migraine

Incidence of Musculoskeletal Disorders, Depression in Migraine

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Fibromyalgia, osteoarthritis, sciatic syndrome, rheumatoid arthritis, and moderate depression may be more prevalent in working-age individuals with vs without migraine.

Neuropathic Pain in Low Back-Related Leg Pain: the State of Evidence

Neuropathic Pain in Low Back-Related Leg Pain: the State of Evidence

A systematic review points to a dearth of evidence regarding the neuropathic etiology of low back-related leg pain.

Pregabalin Not Effective for Sciatica Treatment

Pregabalin Not Effective for Sciatica Treatment

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A randomized trial found that pregabalin is not more effective than placebo in treating sciatica, and resulted in more adverse effects.

Pregabalin for Sciatica: Is It Effective?

Pregabalin for Sciatica: Is It Effective?

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In patients with sciatica pain, treatment with pregabalin did not significantly reduce pain intensity compared with placebo.

Managing Spinal Pain With NSAIDs?

Managing Spinal Pain With NSAIDs?

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Meta-analysis indicates short-term NSAID use is generally safe and can relieve pain, but lacks clinically important benefits.

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