There is a lack of evidence supporting the benefits of combination drug therapy over monotherapy for the management of low back pain and sciatica.
Belief in a long recovery, many symptoms attributed to pain negatively tied to improvement/
Fibromyalgia, osteoarthritis, sciatic syndrome, rheumatoid arthritis, and moderate depression may be more prevalent in working-age individuals with vs without migraine.
A systematic review points to a dearth of evidence regarding the neuropathic etiology of low back-related leg pain.
A randomized trial found that pregabalin is not more effective than placebo in treating sciatica, and resulted in more adverse effects.
In patients with sciatica pain, treatment with pregabalin did not significantly reduce pain intensity compared with placebo.
Meta-analysis indicates short-term NSAID use is generally safe and can relieve pain, but lacks clinically important benefits.
Clinical Pain Advisor Articles
- Supervised Injection Sites: Facts, Information, Pros, and Cons
- Chronic Pain May Be a Contributing Factor to Suicide
- Striking a Balance Between Opioid Surveillance and Patient Privacy
- Demographic Characteristics of Pregnant Women With Opioid Use Disorder
- Effects of Mindfulness Therapy, Pharmacologic Prophylaxis on Catecholamine Levels in Migraine
- Perioperative Pain Management in Patients With Opioid Use Disorder
- Cannabinoid-Associated Analgesia May Be Mediated Through Modulation of Affective Processes
- Seven-Item Pain Intensity Measure Reliable in Individuals With Dementia
- Reviewing the Efficacy of Invasive Procedures for Chronic Back, Knee Pain
- Antidepressant Effects of Ketamine Appear to Require Opioid System Activation
- Predicting Success of Focal Nerve Surgery Based on Diagnostic Block Response
- Aetna-CVS Merger Approved
- FDA Announces Draft Guidance for Consumer OTC Access to Previously Prescription Drugs
- Maryland Legislature: Will Federal Courts Permit State Regulation of Drug Prices?
- Understanding the Cause is Necessary to Treating Physician Burnout