Trospium Chloride Ext-Rel Caps Rx
Generic Name and Formulations:
Trospium chloride 60mg; ext-rel caps.
Various generic manufacturers
Indications for Trospium Chloride Ext-Rel Caps:
Overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency.
Take on empty stomach. 60mg daily in the AM. Severe renal impairment (CrCl<30mL/min): not recommended.
Gastric or urinary retention; uncontrolled narrow-angle glaucoma; and patients at risk for these conditions.
Bladder outflow obstruction. GI obstructive disorders. Ulcerative colitis. Narrow-angle glaucoma (monitor). Intestinal atony. Myasthenia gravis. Exposure to high environmental temperature. Renal insufficiency (CrCl 30–80mL/min). Moderate to severe hepatic dysfunction. Pregnancy (Cat.C). Nursing mothers.
Additive anticholinergic effects with other anticholinergics. Increased drowsiness with alcohol; avoid consumption within 2hrs of administration. May alter absorption of other drugs (decreased GI motility). May potentiate or be potentiated by drugs eliminated by active tubular secretion. May be antagonized by metformin.
Anticholinergic effects (dry mouth, constipation, dry eyes, urinary retention, blurred vision), CNS effects (monitor), dyspepsia, headache.
Formerly known under the brand name Sanctura, Sanctura XR.
Fecal (primarily), renal.
Clinical Pain Advisor Articles
- Abuse-Deterrent Opioid Formulations: Barriers to Broader Use
- Women Frequently Prescribed High Doses of Opioids After Vaginal Delivery
- Notifications by PDMPs May Not Effectively Reduce Opioid Misuse
- Virtual Reality May Effectively Reduce Sensory, Affective, and Cognitive Pain During Labor
- Medical Cannabis Legalization Associated With Reduced Schedule III Opioid Prescriptions
- Neuropathic Pain Medications
- Higher Buprenorphine Dose May Not Increase Severity of Neonatal Abstinence Syndrome
- Terms Used for Addiction May Be Associated With Explicit, Implicit Bias
- Ketamine Infusions May Be Effective for Refractory Headache
- Physical, Psychosocial Activity May Be Protective Against Development of Chronic Pain in Older Adults
- Prioritizing Rest in Hospital Settings: Poor Sleep Increases Costs, Complications, and Mortality
- Pain Catastrophizing Decreases in Rheumatoid Arthritis After DMARD Initiation
- Addressing Commercial Incentives in the Medical Device Industry
- Cancer Patients Treated With Step III Opioids Often Have Sleep Disturbances
- Low Literacy Self-Management Program for Chronic Pain May Be Effective