Recent Highlights In Rheumatology Research Discussed

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Arthritis treatment and sleroderma were noted as some of the top rheumatology issues in the last year.
Arthritis treatment and sleroderma were noted as some of the top rheumatology issues in the last year.

HealthDay News -- Articles relating to arthritis treatment, vasculitides, and scleroderma are included in a special update summary published online April 30 in the Annals of Internal Medicine.

David B. Hellman, MD, from the Johns Hopkins University School of Medicine in Baltimore, and John B. Imboden, MD, from the University of California in San Diego, searched the medical literature and summarized key rheumatology studies published in 2014 that were the highest quality and of most importance to internists.

The authors included articles that provide information about a new therapy for psoriatic arthritis (anti-interleukin-17 receptor A); the most effective strategy for initial treatment and sustaining remission in rheumatoid arthritis; the best ways to sustain remission in antineutrophil cytoplasmic antibody-associated vasculitis; the value of glucocorticoid epidural injections in treating lumbar spinal stenosis; and the long-term safety of hydroxychloroquine. 

Genetic studies performed in families with multiple affected members provided results about the cause of polyarteritis nodosa. Finally, in some patients, scleroderma was identified as a paraneoplastic disease in which cancer is the foreign antigen which triggers the disease.

"We searched the medical literature published in 2014 to identify rigorously performed studies that added important new information about the treatment of rheumatic diseases or provided paradigm-shifting insights into the cause of these diseases," the authors write.

Reference

1. Hellmann DB, et al. Ann Intern Med. 2015; 169(2):W122-126. required)

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