Knee Osteoarthritis May Increase Risk of Hypertension
Incident hypertension was defined as systolic blood pressure >140 mm Hg and/or diastolic blood pressure >90 mm Hg.
Having knee osteoarthritis may increase the likelihood of developing hypertension, according to findings presented at the World Congress on Osteoporosis, Osteoarthritis, and Musculoskeletal Diseases, March 23-26, 2017, in Florence, Italy.1
An international team of researchers from Italy, Belgium, and the United Kingdom collected data from the Osteoarthritis Initiative, a multicenter, longitudinal, observational study. Incident hypertension was defined as systolic blood pressure >140 mm Hg and/or diastolic blood pressure >90 mm Hg. Radiologic and clinical assessment were used to identify knee osteoarthritis.
Of the 3558 patients with normal blood pressure at baseline, 1930 had knee osteoarthritis and 1628 did not. There was a significantly higher incidence of hypertension in patients with knee osteoarthritis compared with patients without osteoarthritis (60 vs 55 per 1000 person years; P <.0001).
After adjustment for confounders, patients with knee osteoarthritis had a 13% higher chance of developing hypertension (hazard ratio [HR] 1.13; 95% CI, 1.01-1.26; P =.03).
“Our data suggest that blood pressure should be monitored in this population and prevent[ive] interventions [be] provided to mitigate the potential adverse consequences of hypertension,” the researchers wrote.
- Vernonese N, Stubbs B, Smith T, Reginster J-Y, Maggi S. The relationship between knee osteoarthritis and incident hypertension: a representative longitudinal study. P222. Presented at: World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases. March 23-26, 2017; Florence, Italy.