Postsurgical Pain

Hydrocodone Schedule Change Affected Post-Operative Opioid Prescriptions

Hydrocodone Schedule Change Affected Post-Operative Opioid Prescriptions

Hydrocodone's change from schedule III to schedule II in 2014 was associated with an increase in the amount of opioids filled in the initial prescription after surgery.

First-in-Class Non-Opioid for Post-Surgical Pain Gets Breakthrough Tx Designation

First-in-Class Non-Opioid for Post-Surgical Pain Gets Breakthrough Tx Designation

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CA-008 is given as a single local injection and works by selectively desensitizing pain-conducting nerve fibers without causing numbness or weakness

Adjunctive Methadone Use May Reduce Post-Spinal Fusion Opioid Requirements in Pediatric Patients

Adjunctive Methadone Use May Reduce Post-Spinal Fusion Opioid Requirements in Pediatric Patients

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Methadone vs desflurane as an adjunct to remifentanil may contribute to reducing perioperative opioid requirements in adolescents undergoing spinal surgery.

Women Frequently Prescribed High Doses of Opioids After Vaginal Delivery

Women Frequently Prescribed High Doses of Opioids After Vaginal Delivery

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Women who undergo vaginal delivery in the United States may frequently be prescribed opioid medications for pain within 1 week of hospital discharge, often dispensed at high doses and in significant quantities.

Preoperative Opioid Use Highly Prevalent, Associated With Age, Tobacco Use

Preoperative Opioid Use Highly Prevalent, Associated With Age, Tobacco Use

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Preoperative opioid use was reported by approximately 23% of patients undergoing surgery, with age, tobacco use, depression, poor life satisfaction, and medical comorbidities identified as independent factors associated with pre-interventional opioid use.

Higher PainDETECT Scores, Neuropathic Pain Preoperatively May Increase Risk for Chronic Pain Post-TKR

Higher PainDETECT Scores, Neuropathic Pain Preoperatively May Increase Risk for Chronic Pain Post-TKR

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Individuals with knee osteoarthritis who have indicators of high vs low/no levels of neuropathic pain may be at elevated risk for chronic pain after total knee replacement surgery.

Optimal Strategies for Opioid Weaning After Ambulatory Surgery

Optimal Strategies for Opioid Weaning After Ambulatory Surgery

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Although there is a scarcity of evidence pertaining to the management of postoperative pain medication in the ambulatory setting, some findings suggest an approach similar to that used for the treatment of acute pain.

Psychosocial Interventions May Improve Outcomes in Orthopedic Surgery

Psychosocial Interventions May Improve Outcomes in Orthopedic Surgery

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Psychosocial interventions such as patient education and relaxation techniques may help reduce pain after orthopedic surgery and improve quality of clinical care.

Benefits of Perioperative IV Lidocaine for Postsurgical Pain Unclear

Benefits of Perioperative IV Lidocaine for Postsurgical Pain Unclear

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Perioperative lidocaine delivered intravenously may not improve pain, gastrointestinal recovery, postoperative nausea, or opioid consumption in the early postoperative phase compared with placebo or no treatment.

Opioid-Free Analgesia Use for Postsurgical Pain Limited

Opioid-Free Analgesia Use for Postsurgical Pain Limited

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The use of opioid-free analgesia to manage postsurgical pain is still limited, particularly in some patient groups that may be at a higher risk for opioid-related adverse drug events.

Factors ID'd for Persistent Opioid Use After Pediatric Surgery

Factors ID'd for Persistent Opioid Use After Pediatric Surgery

With the distinct qualities that come from post-surgical procedures in the realm of pediatrics, conclusions are still being considered.

Recommendations for Perioperative Pain Management in Patients With Opioid Tolerance

Recommendations for Perioperative Pain Management in Patients With Opioid Tolerance

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With the increasing number of patients presenting to surgery with opioid tolerance, clinicians should be familiar with their specific analgesic needs.

Benefit of Liposomal Bupivacaine for Pain in TKA Questioned

Benefit of Liposomal Bupivacaine for Pain in TKA Questioned

Liposomal bupivacaine use in patients undergoing total knee arthroplasty is not associated with clinically meaningful reductions in inpatient opioid use, resource utilization, or opioid-related complications.

Anesthetic-Loaded Bone Cements May Accelerate Post-Reconstruction Recovery

Anesthetic-Loaded Bone Cements May Accelerate Post-Reconstruction Recovery

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Calcium phosphate cement loaded with bupivacaine vs ropivacaine may accelerate functional recovery after bone reconstruction surgery and maintain bone-filling properties.

Regional Anesthesia Tied to Lower Opioid Use in TKA, THA

Regional Anesthesia Tied to Lower Opioid Use in TKA, THA

Regional anesthesia is associated with a lower opioid consumption in both knee and hip replacement surgeries, compared to general anesthesia.

Efficacy of IV Meloxicam for Bunionectomy-Associated Pain

Efficacy of IV Meloxicam for Bunionectomy-Associated Pain

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A once-daily intravenous injection of meloxicam may safely and effectively relieve moderate to severe bunionectomy-associated pain.

Opioid-Related Adverse Drug Events Associated With Worse Patient, Cost Outcomes

Opioid-Related Adverse Drug Events Associated With Worse Patient, Cost Outcomes

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Adverse events associated with opioids administered for the management of postsurgical and postendoscopy pain may be associated with worse cost and patient outcomes.

Phantom Knee Pain

Phantom Knee Pain

Suspecting that this phenomenon might be the source of my nighttime pain, causing significant REM sleep deprivation, I reasoned that a neuromodulator such as a gabapentinoid might be helpful.

Opioids Often Over-Prescribed After Hiatal Hernia Surgery

Opioids Often Over-Prescribed After Hiatal Hernia Surgery

The researchers found that the median prescription size was 350 mg oral morphine equivalents and median patient use was 225 mg oral morphine equivalents following open hiatal hernia repair.

Evaluating Analgesic Benefits of NSAID Combinations for Acute Postoperative Dental Pain

Evaluating Analgesic Benefits of NSAID Combinations for Acute Postoperative Dental Pain

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Acetaminophen in combination with ibuprofen or oxycodone, as well as diclofenac, and flurbiprofen may offer more effective analgesia for acute postoperative dental pain in adults.

Opioids, Sedatives, and the Risk for Cardiopulmonary and Respiratory Arrest

Opioids, Sedatives, and the Risk for Cardiopulmonary and Respiratory Arrest

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Opioids and sedatives may represent independent and additive predictors of cardiopulmonary and respiratory arrest in both medical and surgical patients.

Intraoperative Opioid Doses and Rates of Hospital Readmission

Intraoperative Opioid Doses and Rates of Hospital Readmission

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The use of high doses of opioids — particularly long-acting opioids — during surgery may increase the risk for 30-day readmission.

Prediction Model Shows Accuracy in Estimating Outcomes After Low Back Surgery

Prediction Model Shows Accuracy in Estimating Outcomes After Low Back Surgery

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A multivariable prediction model for outcome after lower back surgery may reliably predict 12-month improvements.

Reviewing the Effectiveness of Lidocaine for the Management of Chronic Pain

Reviewing the Effectiveness of Lidocaine for the Management of Chronic Pain

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Systemic lidocaine administered via IV or patch has consistently shown effectiveness for the treatment and prevention of chronic pain.

Opioid Prescriptions After Surgery: Parameters to Blame for Misuse

Opioid Prescriptions After Surgery: Parameters to Blame for Misuse

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Prescription opioid duration — not dosage — following surgery may be associated with a greater risk for opioid misuse in patients with no prior history of opioid use.

Disposal of Unused Opioids After Surgery Improved With Educational Brochure

Disposal of Unused Opioids After Surgery Improved With Educational Brochure

Disseminating an educational brochure improves disposal of unused opioids after surgery.

Potential Opioid Overprescription May Be Common After Most Surgical Procedures

Potential Opioid Overprescription May Be Common After Most Surgical Procedures

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Opioids may be overprescribed frequently after surgery in most specialties.

Perioperative Gabapentin May Modestly Promote Postoperative Opioid Cessation

Perioperative Gabapentin May Modestly Promote Postoperative Opioid Cessation

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Compared with placebo, gabapentin administered pre- and postoperatively may reduce the time to postoperative opioid cessation, but was not shown to improve postoperative pain resolution.

Statins Ineffective in Reducing Pain, Opioid Consumption After Hip Surgery

Statins Ineffective in Reducing Pain, Opioid Consumption After Hip Surgery

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The use of statins after hip surgery may not reduce pain levels or the need for opioids.

Chronic Postoperative Pain Risk Linked to Gene Polymorphisms

Chronic Postoperative Pain Risk Linked to Gene Polymorphisms

Genetics may be a factor in the experience of chronic postoperative pain as 42 polymorphisms were found to be correlated with chronic postsurgical pain.

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