Post-Surgical Pain

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Predicting Acute Pain After Cesarean Delivery to Reduce Risk for Persistent Pain

Predicting Acute Pain After Cesarean Delivery to Reduce Risk for Persistent Pain

The most promising tools to predict acute pain after cesarean delivery are local anesthetic infiltration before placement of spinal anesthesia, and asking patients simple questions about anticipated pain and analgesic needs.

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Clinical Pain Assessment Tools May Not Be Useful in Sedated Patients in the ICU

Clinical Pain Assessment Tools May Not Be Useful in Sedated Patients in the ICU

The Critical-Care Pain Observation Tool and the Behavioral Pain Scale may not be optimal tools to assess pain levels in agitated or sedated patients in intensive care units.

Reverse Total Shoulder Arthroplasty: Long-Term Clinical, Subjective Outcomes

Reverse Total Shoulder Arthroplasty: Long-Term Clinical, Subjective Outcomes

Reverse total shoulder arthroplasty in patients with irreparable rotator cuff tear may lead to long-term improvements in range of motion and pain levels, but may be associated with high rates of complications.

No Added Benefit for Acupuncture in Routine Rehabilitation After Total Knee Replacement

No Added Benefit for Acupuncture in Routine Rehabilitation After Total Knee Replacement

The addition of adjunctive acupuncture to routine rehabilitation therapy after total knee replacement may not provide a significant benefit over exercise only for relieving postoperative pain.

Handover of Intraoperative Anesthesia Care Linked to Increase in Adverse Postoperative Outcomes

Handover of Intraoperative Anesthesia Care Linked to Increase in Adverse Postoperative Outcomes

Complete handover of intraoperative anesthesia care is associated with an increased risk of adverse postoperative outcomes among adults undergoing major surgery.

Perioperative Gabapentin May Modestly Promote Postoperative Opioid Cessation

Perioperative Gabapentin May Modestly Promote Postoperative Opioid Cessation

Compared with placebo, gabapentin administered pre- and postoperatively may reduce the time to postoperative opioid cessation, but was not shown to improve postoperative pain resolution.

Intravenous Acetaminophen May Reduce Hospital Length of Stay in Adolescents Undergoing Posterior Spinal Fusion

Intravenous Acetaminophen May Reduce Hospital Length of Stay in Adolescents Undergoing Posterior Spinal Fusion

Postoperative management of adolescents undergoing posterior spinal fusion surgery with intravenous acetaminophen may have an opioid-sparing effect, due to a reduced hospital length of stay.

Statins Ineffective in Reducing Pain, Opioid Consumption After Hip Surgery

Statins Ineffective in Reducing Pain, Opioid Consumption After Hip Surgery

The use of statins after hip surgery may not reduce pain levels or the need for opioids.

Chronic Postoperative Pain Risk Linked to Gene Polymorphisms

Chronic Postoperative Pain Risk Linked to Gene Polymorphisms

Genetics may be a factor in the experience of chronic postoperative pain as 42 polymorphisms were found to be correlated with chronic postsurgical pain.

Preoperative Cholesterol Levels Not Linked With Laparoscopic Postoperative Pain

Preoperative Cholesterol Levels Not Linked With Laparoscopic Postoperative Pain

Preoperative levels of serum total cholesterol do not correlate with postoperative pain following laparoscopic surgery for gastric cancer.

Opioid Prescribing vs Consumption Following Rhinoplasty

Opioid Prescribing vs Consumption Following Rhinoplasty

Patients used only 40% of the hydrocodone-acetaminophen combination tablets prescribed to them following rhinoplasty.

Postoperative Pain Management in Children With Developmental Delay

Postoperative Pain Management in Children With Developmental Delay

Parent- and nurse-controlled analgesia may not reduce postoperative pain in children with developmental delay compared with opioids administered by a nurse as needed.

Smoking Cessation May Increase Postoperative Opioid Use

Smoking Cessation May Increase Postoperative Opioid Use

Abstinent smokers may have reduced preoperative pain tolerance and increased postoperative opioid use compared with nonsmokers.

Fast Track Designation Granted for Post-Surgical Pain Medication

Fast Track Designation Granted for Post-Surgical Pain Medication

The FDA has granted Fast Track Designation to the investigational treatment CA-008 (Concentric Analgesics) for the treatment of post-surgical pain.

Lower Surgical Pleth Index Target Provides Better Estimate of Pediatric Postsurgical Pain

Lower Surgical Pleth Index Target Provides Better Estimate of Pediatric Postsurgical Pain

A Surgical Pleth Index target level lower than that reported in the current literature may be more appropriate in research studies examining SPI-guided anesthesia in pediatric patients.

Opioid Prescribing Suboptimal in Setting of Enhanced Recovery After Surgery

Opioid Prescribing Suboptimal in Setting of Enhanced Recovery After Surgery

Implementation of an enhanced recovery after surgery protocol resulted in an increase in opioid-free anesthesia and multimodal analgesia, but did not modify opioid prescribing practices.

New Drug Application Submitted for Olinvo to Treat Acute Pain

New Drug Application Submitted for Olinvo to Treat Acute Pain

Trevena has submitted their New Drug Application to the FDA for Olinvo, an oliceridine injection, for the management of moderate-to-severe pain in the hospital and similar settings.

Intraoperative Naloxone Reduces Remafentanil-Induced Postoperative Hyperalgesia

Intraoperative Naloxone Reduces Remafentanil-Induced Postoperative Hyperalgesia

Intraoperative low-dose naloxone reduced postoperative hyperalgesia but had no effect on pain when combined with high-dose remifentanil for elective thyroid surgery.

Midazolam Plus Morphine: Continuous vs Intermittent Infusions for Pediatric Postsurgical Pain

Midazolam Plus Morphine: Continuous vs Intermittent Infusions for Pediatric Postsurgical Pain

Continuous infusions of midazolam plus morphine do not provide additional pain relief compared with intermittent dosing of those drugs, and may increase hospital length of stay among pediatric patients who have undergone cardiac surgery.

Intraoperative Esmolol Decreases Intraoperative, Postoperative Opioid Use

Intraoperative Esmolol Decreases Intraoperative, Postoperative Opioid Use

Esmolol was shown to reduce the use of opioids during and after surgery without having a significant impact on postoperative pain scores.

Ibuprofen Comparable With Morphine for Postoperative Pain in Children

Ibuprofen Comparable With Morphine for Postoperative Pain in Children

Among children who have undergone minor outpatient orthopedic surgery, ibuprofen provides equivalent postoperative pain relief compared with oral morphine.

Liposomal Bupivacaine Effective for Shoulder Arthroplasty-Related Pain

Liposomal Bupivacaine Effective for Shoulder Arthroplasty-Related Pain

Among patients undergoing shoulder arthroplasty, liposomal bupivacaine was shown to provide better pain relief at 19 to 21 weeks post-surgery with fewer complications compared with continuous interscalene nerve block.

Systemic Lidocaine May Be Effective for Postmastectomy Pain

Systemic Lidocaine May Be Effective for Postmastectomy Pain

Intraoperative systemic lidocaine may reduce chronic persistent postmastectomy pain at 6 months after surgery.

Intra-Articular Anesthesia Reduces Pain After Arthroscopic Hip Surgery

Intra-Articular Anesthesia Reduces Pain After Arthroscopic Hip Surgery

In addition to preoperative femoral nerve block, the use of intra-articular anesthetic injections during arthroscopic hip surgery may offer effective post-procedural pain relief and be associated with a reduced risk for postoperative falls.

Thoracic Epidural Analgesia Effective After Multi-Organ Surgery

Thoracic Epidural Analgesia Effective After Multi-Organ Surgery

Thoracic epidural analgesia is associated with greater pain control, lower need for narcotics, and fewer complications after hepatopancreatobiliary surgery compared with intravenous patient-controlled analgesia.

Electrotherapy, Acupuncture May Decrease Pain Following Total Knee Arthroplasty

Electrotherapy, Acupuncture May Decrease Pain Following Total Knee Arthroplasty

Electrotherapy and acupuncture were both found to reduce and delay opioid consumption after total knee arthroplasty.

Psychological Factors, Not Opioid Use, Linked with Disability After Fracture Surgery

Psychological Factors, Not Opioid Use, Linked with Disability After Fracture Surgery

Post-operative opioid therapy may not be necessary for patients undergoing ankle surgery.

Optimal Pain Management After Total Knee Arthroplasty

Optimal Pain Management After Total Knee Arthroplasty

In patients undergoing total knee arthroplasty, sciatic nerve block plus femoral nerve block was more effective for pain relief than local infiltration analgesia plus femoral nerve block.

Inpatient Rehabilitation Effective After Total Knee Arthroplasty?

Inpatient Rehabilitation Effective After Total Knee Arthroplasty?

Inpatient rehabilitation did not improve mobility among adult patients undergoing uncomplicated total knee arthroplasty at 26 weeks after surgery compared with a home-based monitoring program

Opioid Use Before TKA Associated With Worse Pain After Surgery

Opioid Use Before TKA Associated With Worse Pain After Surgery

Patients taking opioids before total knee arthroplasty may have greater pain after the procedure.

Auricular Point Acupressure Reduces Axial Neck Pain

Auricular Point Acupressure Reduces Axial Neck Pain

Auricular point acupressure may help relieve axial neck pain in patients who have undergone anterior cervical discectomy and fusion.