"Our study shows that clinically significant placebo effects can be produced even when patients are told that they are being given placebos."
Because the increased cytokine levels in the acute phase of herpes zoster are assumed to be a potential mechanism for inducing PHN, the early suppression of these cytokines by LLLT may help prevent the development of PHN.
"Dose-extending placebo use is based on learning principles and schedules of reinforcement, so that conditioned stimuli acquire properties and characteristics of unconditioned stimuli," Dr Colloca told Clinical Pain Advisor.
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