Euphoria associated with the stimulant methylphenidate may be mitigated by co-administration of naltrexone in patients with attention-deficit/hyperactivity disorder.
Pharmacologic-only approaches to the management of chronic pain seldom provide complete/adequate pain relief and experts advocate for an integrative approach to the management of chronic pain.
New evidence suggests that stopping antibiotics sooner is a safe and effective way to reduce antibiotic overuse.
Boehringer Ingelheim has initiated a clinical study to investigate the interchangeability between an adalimumab biosimilar candidate and Humira.
There is good evidence for cognitive behavioral therapy and motivational approaches to dependence.
These findings highlight an urgent need to produce more evidence on the risks and benefits of off-label antidepressant use.
Much of the third world is suffering in pain without access to opioids. This imbalance has been called the opioid gap. How can we get opioids to patients who need them?
A recent study published in The Journal of Pain evaluated the effectiveness of a brief self-assessment tool called the Opioid Compliance Checklist in identifying adherence, or misuse, among patients prescribed opioids.
The drug assists the kidney excrete uric acid by impeding the function of transporter proteins involved in uric acid reabsorption in the kidney.
PAMORA strategy appears to safe with superior effectiveness.
Two new studies shed more light on whether of aspirin can help treat breast cancer patients.
Pharmacogenetic testing yields information that informs how an individual will metabolize medications.
Exposing clinicians to a multifaceted risk-reduction initiative significantly shifts prescribing practices away from high-dose chronic opioid therapy.
The FDA approval process requires 3 elements: efficacy, safety, and ability to manufacture quality product reproducibly.
Isovaline may be a new alternative to opioids for anesthesia and procedural sedation, new data published in Anesthesia & Analgesia has shown.
Treating painful conditions typically requires an approach that uses a variety of methods.
Significant reduction in drug-related problems with immediate communication of recommendations.
Clinical and community-based approaches should be used to increase aspirin use among low-use groups.
No indication any particular type of antidepressant carries a greater risk than others.
Patients who use of multiple pharmacies concurrently (pharmacy shopping) and have overlapping prescriptions for opioid medications have a greater risk of opioid overdose events.
If a compound does not pass an initial screen, a switch can be requested.
Researchers find testing blood from mouth is as accurate as finger prick at diagnosing condition
Clinical Pain Advisor Articles
- Replacing Sleep, Sedentary Behavior With Physical Activity Beneficial in Knee Osteoarthritis
- The Role of Psychological Factors in Phantom Limb Pain Reviewed
- FDA Outlines Plan for New Analgesic Guidance to Combat Opioid Crisis
- Ozone vs Corticosteroids May Provide Longer-Lasting Effects for Plantar Fasciitis
- Rates of Concurrent Opioid, Sedative-Hypnotic Prescription Fills in Veterans
- Ketamine: Mechanisms of Action, Uses in Pain Medicine, and Side Effects
- Cannabis May Be Effective for Migraine Treatment
- Medicinal Cannabis May Not Have Opioid-Sparing Effects in Chronic Noncancer Pain
- Integrating Psychological Interventions Into Chronic Pain Management
- Chronic Neck Pain: Generators, Clinical Examination, MRI Findings, and Differential Diagnosis
- Pregabalin May Not Improve Analgesia During Medical Abortion
- Investigational Treatment Shows Promise in Chronic Low Back Pain
- Rheumatologist-Assessed vs Criteria for Inflammatory Back Pain in Psoriatic Arthritis
- Incorporating Guidelines Into Clinical Practice: An Interview With Gary L. LeRoy, MD
- Pain Severity May Partly Mediate the Association Between Depression and Physical Performance in Knee OA