Multiple exposures to anesthesia before the age of 3 years may have neuropsychological impacts, though intelligence does not appear to be affected.
The approval was based on a 12-week, double-blind, placebo-controlled study (N=295) in pediatric patients 4-17 years of age.
Since the legalization of medical marijuana, clinicians must come up with appropriate responses to requests for treatment in pediatric end-of-life settings.
Youths between the ages of 8 and 17 who suffer from multiple pain sites may be at risk for poorer emotional, physical, and educational functioning compared with youths who experience pain at a single site.
Lidocaine gel may not provide substantial advantage over nonanesthetic gel for reducing pain associated with transurethral bladder catheterization in children aged <4 years.
The Modified Behavioral Pain Scale may represent a reliable tool for assessing procedural pain but may not allow to discriminate between pain- and non-pain-related distress in infants and young children.
Intravenous Acetaminophen May Reduce Hospital Length of Stay in Adolescents Undergoing Posterior Spinal FusionJanuary 16, 2018
Postoperative management of adolescents undergoing posterior spinal fusion surgery with intravenous acetaminophen may have an opioid-sparing effect, due to a reduced hospital length of stay.
ACTTION Consensus Provides Best Practices for the Design of Pediatric Clinical Trials Focused on Acute PainJanuary 08, 2018
Key factors susceptible to improve the design of clinical trials on analgesics for acute pain in pediatric populations were reviewed and recommendations published.
Parent- and nurse-controlled analgesia may not reduce postoperative pain in children with developmental delay compared with opioids administered by a nurse as needed.
Peripheral nerve blocks for pediatric headache treatment are associated with significant benefit and minimal risk.
Catastrophic thinking about pain in children may mediate the relationship between chronic pain and posttraumatic stress disorder in both children and parents.
Anxiety and reduced readiness to change are key factors related to nonresponsiveness to intensive pain rehabilitation in pediatric patients.
The Verbal Numerical Rating Scale represents a useful clinical tool for the assessment of pain intensity in pediatric patients with painful and non-painful medical conditions.
Fewer randomized controlled trials include children vs adult cohorts, and the evidence pertaining to this population.
Continuous infusions of midazolam plus morphine do not provide additional pain relief compared with intermittent dosing of those drugs, and may increase hospital length of stay among pediatric patients who have undergone cardiac surgery.
Neurostimulation through percutaneous electrical nerve field stimulation was shown to durably reduce pain in children.
No conclusive evidence was found supporting the efficacy of antidepressants in the pediatric population.
An association was found between sleep quality and next-day pain intensity in children undergoing major surgery.
In a comparative study, topical liposomal lidocaine proved most effective for analgesia during infant vaccination.
Meta-analysis shows reduction in pain and crying time for neonates, but most trials still include a placebo/no-tx arm.
Parents' experiences impacted by need to balance pros and cons of administering medicines.
Clinical Pain Advisor Articles
- Abuse-Deterrent Opioid Formulations: Barriers to Broader Use
- Women Frequently Prescribed High Doses of Opioids After Vaginal Delivery
- Notifications by PDMPs May Not Effectively Reduce Opioid Misuse
- Virtual Reality May Effectively Reduce Sensory, Affective, and Cognitive Pain During Labor
- Medical Cannabis Legalization Associated With Reduced Schedule III Opioid Prescriptions
- Neuropathic Pain Medications
- Higher Buprenorphine Dose May Not Increase Severity of Neonatal Abstinence Syndrome
- Terms Used for Addiction May Be Associated With Explicit, Implicit Bias
- Ketamine Infusions May Be Effective for Refractory Headache
- Physical, Psychosocial Activity May Be Protective Against Development of Chronic Pain in Older Adults
- Prioritizing Rest in Hospital Settings: Poor Sleep Increases Costs, Complications, and Mortality
- Pain Catastrophizing Decreases in Rheumatoid Arthritis After DMARD Initiation
- Addressing Commercial Incentives in the Medical Device Industry
- Cancer Patients Treated With Step III Opioids Often Have Sleep Disturbances
- Low Literacy Self-Management Program for Chronic Pain May Be Effective