Opioids

Risk Factors Associated With Chronic Opioid Use in Musculoskeletal Pain

Risk Factors Associated With Chronic Opioid Use in Musculoskeletal Pain

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The chronic use of opioids was found to be low in individuals with musculoskeletal pain, and to have decreased from 2008 to 2014.

More Than Two-Thirds of Drug OD Deaths in 2017 Involved Opioids

More Than Two-Thirds of Drug OD Deaths in 2017 Involved Opioids

More than two-thirds of drug overdose deaths in 2017 involved an opioid, with increases in overdose deaths from all opioids and synthetic opioids seen from 2016 to 2017.

Reviewing the Use of Buprenorphine in Perioperative Pain Management

Reviewing the Use of Buprenorphine in Perioperative Pain Management

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The perioperative use of µ-opioid agonists and continuation of buprenorphine treatment in patients on buprenorphine therapy were found to be safe for the management of postsurgical pain.

CBT Program Effective for Chronic Pain and Opioid Use Disorder

CBT Program Effective for Chronic Pain and Opioid Use Disorder

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Cognitive behavioral therapy was found to be more effective in reducing the use of nonmedical opioids compared with standard methadone drug counseling in patients with chronic pain and opioid use disorder enrolled in methadone maintenance treatment programs.

Smaller Heads Related to Opioid-Related Neonatal Abstinence Syndrome

Smaller Heads Related to Opioid-Related Neonatal Abstinence Syndrome

Chronic opioid use during pregnancy that causes neonatal abstinence syndrome (NAS) is associated with smaller neonatal head circumference.

Dental Procedure-Related Opioid Exposure and Later Risk for Opioid Abuse

Dental Procedure-Related Opioid Exposure and Later Risk for Opioid Abuse

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A substantial proportion of adolescent and young adults receiving opioids for dental procedures may be at higher risk for later opioid use and abuse.

Prevalence of Benzodiazepine Use, Misuse Among US Adults Analyzed

Prevalence of Benzodiazepine Use, Misuse Among US Adults Analyzed

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Alprazolam was found to be the most commonly misused benzodiazepine.

reSET-O Digital Therapeutic for Opioid Use Disorder Now Available

reSET-O Digital Therapeutic for Opioid Use Disorder Now Available

Sandoz and Pear Therapeutics announced the launch of reSET-O, a new digital therapeutic for patients aged ≥18 years with opioid use disorder (OUD) currently under clinician care.

A Case for Ministerial Recall of High-Strength Opioids in Canada

A Case for Ministerial Recall of High-Strength Opioids in Canada

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The Protecting Canadians from Unsafe Drugs Act passed into law in 2014 empowered the minister of health to recall a drug if they "believe that a therapeutic product presents a serious or imminent risk of injury to health."

Nonmedical Prescription Opioid Use Motivated by Pain Relief in Adolescence Predicts Later SUD

Nonmedical Prescription Opioid Use Motivated by Pain Relief in Adolescence Predicts Later SUD

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A set of characteristics of nonmedical use of prescription opioids in adolescents may help identify youth at high risk for substance use disorder, including opioid misuse, in early midlife.

Physical, Sexual Abuse and Concurrent Opioid/Benzodiazepine Use in Chronic Pain

Physical, Sexual Abuse and Concurrent Opioid/Benzodiazepine Use in Chronic Pain

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Patients with chronic pain and a history of physical and sexual abuse were found to be more likely to concurrently use benzodiazepine and opioids.

HIV Patients Misusing Opioids Have Poorer Health Outcomes

HIV Patients Misusing Opioids Have Poorer Health Outcomes

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Researchers found substantial room for improvement in the delivery of substance use and mental health counseling and treatment and HIV/STD prevention counseling.

Increase Seen in Amphetamine, Opioid Use in Pregnant Women

Increase Seen in Amphetamine, Opioid Use in Pregnant Women

The incidence of amphetamine and opioid use has increased among pregnant women, especially in rural counties.

CDC: Top 10 Drugs Involved in Drug Overdose Deaths

CDC: Top 10 Drugs Involved in Drug Overdose Deaths

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Using data from the 2011 to 2016 National Vital Statistics System-Mortality files, the authors conducted a literal text analysis of death certificates to identify drugs mentioned as contributing to the cause of overdose death.

Monthly Injections of Naltrexone, Opioid Antagonist, Superior to Oral Design

Monthly Injections of Naltrexone, Opioid Antagonist, Superior to Oral Design

Heroin addicts were more compliant with taking monthly injections of naltrexone rather than consuming it in a pill version.

Additional Naloxone Formulation Submitted to FDA for Review

Additional Naloxone Formulation Submitted to FDA for Review

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Currently, naloxone is supplied in ampules and vials for IV, IM or SC administration, in a prefilled auto-injector, and as a nasal spray.

Opioid Use Disorder Associated With Greater Complications After Cardiac Surgery

Opioid Use Disorder Associated With Greater Complications After Cardiac Surgery

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Among patients undergoing cardiac surgery, those with vs without opioid use disorder may have higher rates of complications and encounter greater costs.

Brixadi Gets Tentative FDA Approval for Opioid Use Disorder

Brixadi Gets Tentative FDA Approval for Opioid Use Disorder

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Brixadi utilizes FluidCrystal Injection Depot Technology; once in contact with fluids in the tissue, the solution turns into a nanostructured liquid-crystalline gel allowing for slow release of buprenorphine at a steady rate over 1 week or 1 month.

Ultrarestrictive Opioid Prescription Protocol May Be Effective for Postoperative Pain Management

Ultrarestrictive Opioid Prescription Protocol May Be Effective for Postoperative Pain Management

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Implementation of an ultrarestrictive protocol for opioid prescriptions was found to be associated with reductions in the amount of opioids prescribed after abdominal and gynecologic surgery.

Chronic Opioid Use Among Rheumatoid Arthritis Patients Rising

Chronic Opioid Use Among Rheumatoid Arthritis Patients Rising

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Using the Corrona RA registry, researchers from Brigham and Women's Hospital, Boston, identified chronic opioid users through surveys completed at study visits.

Addiction Medicine Consultation Improves Antibiotic Compliance in Patients With Opioid Use Disorders

Addiction Medicine Consultation Improves Antibiotic Compliance in Patients With Opioid Use Disorders

Patients with opioid use disorders who required hospitalization with lengthy antibiotic therapy had better outcomes with addiction medicine consultation.

Evzio Authorized Generic Soon to Be Available

Evzio Authorized Generic Soon to Be Available

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In addition to the new authorized generic, Evzio is now available at $178 per carton (2 auto-injectors per carton) for government agencies, first responders, health departments, and other qualifying groups when they purchase directly from kaléo or authorized distributors.

Prescription Digital Therapeutic Approved for Opioid Use Disorder

Prescription Digital Therapeutic Approved for Opioid Use Disorder

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reSET-O is intended for use as an adjunct to outpatient treatment that includes transmucosal buprenorphine (medication-assisted-treatment [MAT]) and contingency management for patients aged ≥18 years who are currently under clinician supervision.

Pediatric Opioid Prescriptions Have Declined Since 2012

Pediatric Opioid Prescriptions Have Declined Since 2012

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After increasing for several years, pediatric opioid prescriptions have been decreasing since 2012 in the United States.

Intrathecal Drug Delivery Systems May Be Ineffective for Complex Regional Pain Syndrome

Intrathecal Drug Delivery Systems May Be Ineffective for Complex Regional Pain Syndrome

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Intrathecal drug delivery systems may be ineffective in reducing pain and oral opioid intake in individuals with complex regional pain syndrome.

Opioid, Nonopioid Utilization Management for Low Back Pain Prevalent in Major Health Plans

Opioid, Nonopioid Utilization Management for Low Back Pain Prevalent in Major Health Plans

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Utilization management strategies for opioid and nonopioid medications in low back pain, including quantity limits and prior authorization, were found to be commonly used in Medicaid, Medicare Advantage, and commercial insurance plans.

Opioid Users More Likely to Have Complex Health Issues and Dealings With Criminal Justice System

Opioid Users More Likely to Have Complex Health Issues and Dealings With Criminal Justice System

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Individuals taking opioids were found to be more likely to report physical and mental health issues and to have more frequent dealings with the criminal justice system compared with individuals not taking opioids.

Debunking Myths Around Treatment for Opioid Use Disorder

Debunking Myths Around Treatment for Opioid Use Disorder

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Primary care office-based addiction treatment of opioid use disorder with buprenorphine is a realistic and scalable solution to address the overdose crisis in the United States.

Postpartum Pain Management Recommendations From the American College of Obstetricians and Gynecologists

Postpartum Pain Management Recommendations From the American College of Obstetricians and Gynecologists

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A committee from the American College of Obstetricians and Gynecologists formulated several recommendations for safely managing pain and fatigue in women during the early postpartum period.

Methadone Improves Short-Term Outcomes Better Than Morphine in Neonatal Abstinence Syndrome

Methadone Improves Short-Term Outcomes Better Than Morphine in Neonatal Abstinence Syndrome

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Methadone may be superior to morphine for reducing hospital length of stay and length of drug treatment in infants with neonatal abstinence syndrome.

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