Opioids

Parents Conflicted About Opioid Use in Children

Parents Conflicted About Opioid Use in Children

Parents are conflicted about the use of prescribed opioids in children, with most concerned about side effects and risks but believing opioids are the most effective option for managing pain.

Examining the Relationships Among Opioid Use, Overdose, and Suicide

Examining the Relationships Among Opioid Use, Overdose, and Suicide

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Opioid-related mortality in the United States has increased at an alarming rate during the last 2 decades as a result of both suicide and unintentional overdose.

Tobacco Users More Likely to Be Co-Prescribed Opioids With Benzodiazepines, Muscle Relaxants

Tobacco Users More Likely to Be Co-Prescribed Opioids With Benzodiazepines, Muscle Relaxants

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Patients with non-cancer back or neck pain who use vs do not use tobacco may be more likely to be concurrently prescribed opioid analgesics with muscle relaxants and/or benzodiazepines.

County-Level Rates of Neonatal Abstinence Syndrome Indicative of Regional Unemployment Rates

County-Level Rates of Neonatal Abstinence Syndrome Indicative of Regional Unemployment Rates

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Higher county-level rates of neonatal abstinence syndrome were associated with a regional shortage of mental health clinicians and high unemployment rates.

Does Opioid Tapering in Chronic Pain Result in Controlled Pain at Taper Completion?

Does Opioid Tapering in Chronic Pain Result in Controlled Pain at Taper Completion?

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Opioid tapering may result in an alleviation of chronic pain, but this notion is based on low-level evidence.

Buprenorphine May Be an Optimal Treatment for Neonatal Abstinence Syndrome

Buprenorphine May Be an Optimal Treatment for Neonatal Abstinence Syndrome

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To identify the most effective treatment for NAS, study authors searched various databases for RCTs where a pharmacological agent was used alone or in combination with adjuvant treatments.

Patients With Chronic Pain Found to Continue Opioids Despite Little Clinical Improvement

Patients With Chronic Pain Found to Continue Opioids Despite Little Clinical Improvement

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Patients initially prescribed opioids for chronic noncancer pain were found to continue the treatment over long periods of time, despite poor clinical improvement.

CDC: Opioid Prescribing Higher in Rural vs Urban Areas

CDC: Opioid Prescribing Higher in Rural vs Urban Areas

The percentage of individuals prescribed an opioid is higher in rural than urban areas.

Marketing of Opioids Linked to Increased Overdose Mortality

Marketing of Opioids Linked to Increased Overdose Mortality

Marketing of opioids to physicians is associated with increased mortality from opioid overdoses.

Ketamine Noninferior to Fentanyl for Traumatic Injury Pain in Children

Ketamine Noninferior to Fentanyl for Traumatic Injury Pain in Children

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Intranasal ketamine was found to be noninferior to intranasal fentanyl for providing analgesia in children presenting to the emergency department with acute injuries of the extremities.

Opioid-Related Pediatric Deaths Increased 3-Fold Between 1999 and 2016

Opioid-Related Pediatric Deaths Increased 3-Fold Between 1999 and 2016

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The rate of pediatric mortality associated with prescription and illicit opioids rose 3-fold between 1999 and 2016.

Extended-Release Naltrexone Improves Psychiatric Disorders During Addiction Therapy

Extended-Release Naltrexone Improves Psychiatric Disorders During Addiction Therapy

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Changes in anxiety, depression, or insomnia symptoms were examined in patients with opioid use disorder taking extended-release naltrexone or buprenorphine-naloxone.

Case Study Report: Herbal Supplement Kratom Associated With Neonatal Abstinence Syndrome

Case Study Report: Herbal Supplement Kratom Associated With Neonatal Abstinence Syndrome

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Pediatricians need to ask about nonprescription substance use during pregnancy when taking histories from mothers with opioid dependence to better care for their newborns.

An Evidence-Based Road Map to Navigating the Opioid Epidemic

An Evidence-Based Road Map to Navigating the Opioid Epidemic

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This rise in prescribing of prescription opioids in the last 2 decades of the 20th century occurred at a time during which medical professionals were urged to resort to prescription opioids to manage untreated and chronic noncancer pain.

Discharge One Hour After Naloxone for OD May Be Option

Discharge One Hour After Naloxone for OD May Be Option

A rule with six criteria can determine whether patients can be safely discharged from the emergency department after a one-hour observation period following prehospital naloxone administration.

AHA Online Opioid Education Course Available

AHA Online Opioid Education Course Available

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The American Heart Association launched in December 2018 a 30 minute-long online course titled "Opioid Education for Healthcare Providers."

As Shutdown Drags On, Opioid Crisis Looms Large

As Shutdown Drags On, Opioid Crisis Looms Large

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As the government shutdown drags in to its second month, physicians who treat opioid use disorders are being backed against a wall.

Factors Associated With Opioid Prescribing Patterns in Pediatric Patients

Factors Associated With Opioid Prescribing Patterns in Pediatric Patients

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Rates of opioid prescriptions to pediatric patients in the emergency department were found to have declined between 2011 and 2015.

Benzodiazepines, if Prescribed, May Not Affect Methadone Treatment Retention

Benzodiazepines, if Prescribed, May Not Affect Methadone Treatment Retention

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The use of benzodiazepine, only if prescribed, may not affect retention of methadone medication-assisted treatment.

When Opioid Prescribing Guidelines Become Rules

When Opioid Prescribing Guidelines Become Rules

Understanding the current opioid prescribing rules is necessary for clinicians to safely and effectively treat patients with chronic pain conditions.

Buprenorphine-Naloxone Found to Be More Cost-Effective Than Extended-Release Naltrexone

Buprenorphine-Naloxone Found to Be More Cost-Effective Than Extended-Release Naltrexone

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Buprenorphine-naloxone may be more cost-effective than extended-release naltrexone as first-line treatment for opioid use disorder.

Risk Factors Associated With Chronic Opioid Use in Musculoskeletal Pain

Risk Factors Associated With Chronic Opioid Use in Musculoskeletal Pain

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The chronic use of opioids was found to be low in individuals with musculoskeletal pain, and to have decreased from 2008 to 2014.

More Than Two-Thirds of Drug OD Deaths in 2017 Involved Opioids

More Than Two-Thirds of Drug OD Deaths in 2017 Involved Opioids

More than two-thirds of drug overdose deaths in 2017 involved an opioid, with increases in overdose deaths from all opioids and synthetic opioids seen from 2016 to 2017.

Reviewing the Use of Buprenorphine in Perioperative Pain Management

Reviewing the Use of Buprenorphine in Perioperative Pain Management

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The perioperative use of µ-opioid agonists and continuation of buprenorphine treatment in patients on buprenorphine therapy were found to be safe for the management of postsurgical pain.

CBT Program Effective for Chronic Pain and Opioid Use Disorder

CBT Program Effective for Chronic Pain and Opioid Use Disorder

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Cognitive behavioral therapy was found to be more effective in reducing the use of nonmedical opioids compared with standard methadone drug counseling in patients with chronic pain and opioid use disorder enrolled in methadone maintenance treatment programs.

Smaller Heads Related to Opioid-Related Neonatal Abstinence Syndrome

Smaller Heads Related to Opioid-Related Neonatal Abstinence Syndrome

Chronic opioid use during pregnancy that causes neonatal abstinence syndrome (NAS) is associated with smaller neonatal head circumference.

Dental Procedure-Related Opioid Exposure and Later Risk for Opioid Abuse

Dental Procedure-Related Opioid Exposure and Later Risk for Opioid Abuse

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A substantial proportion of adolescent and young adults receiving opioids for dental procedures may be at higher risk for later opioid use and abuse.

Prevalence of Benzodiazepine Use, Misuse Among US Adults Analyzed

Prevalence of Benzodiazepine Use, Misuse Among US Adults Analyzed

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Alprazolam was found to be the most commonly misused benzodiazepine.

reSET-O Digital Therapeutic for Opioid Use Disorder Now Available

reSET-O Digital Therapeutic for Opioid Use Disorder Now Available

Sandoz and Pear Therapeutics announced the launch of reSET-O, a new digital therapeutic for patients aged ≥18 years with opioid use disorder (OUD) currently under clinician care.

A Case for Ministerial Recall of High-Strength Opioids in Canada

A Case for Ministerial Recall of High-Strength Opioids in Canada

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The Protecting Canadians from Unsafe Drugs Act passed into law in 2014 empowered the minister of health to recall a drug if they "believe that a therapeutic product presents a serious or imminent risk of injury to health."

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