Opioids

Opioid Prescribing Trends in Patients With, Without Cancer

Opioid Prescribing Trends in Patients With, Without Cancer

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Individuals with and without cancer may be affected in a similar manner by concerns surrounding opioids that have led to reductions in their prescribing.

Widespread Impact of Reducing Opioids, Adding IV Acetaminophen for Postsurgical Pain Management

Widespread Impact of Reducing Opioids, Adding IV Acetaminophen for Postsurgical Pain Management

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Postoperative pain management that combines a reduction of opioids with the use of intravenous acetaminophen may shorten hospital length of stay, reduce the rate of complications related to opioids, and lower related costs.

How the City of San Francisco Is Tackling the Intertwined HIV/HCV and Opioid Epidemics

How the City of San Francisco Is Tackling the Intertwined HIV/HCV and Opioid Epidemics

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Katie Burk, MPH, presented measures undertaken by the city of San Francisco to provide integrated responses to the concurrent HIV/HCV and opioid public health epidemics.

The State of Drug Storage, Disposal Labeling Information for Opioid Analgesics

The State of Drug Storage, Disposal Labeling Information for Opioid Analgesics

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Package inserts of opioid analgesics may not consistently provide information regarding safe drug storage and/or disposal.

Tackling the Chronic Pain and Opioid Use Disorder Crises Through Public-Private Partnerships

Tackling the Chronic Pain and Opioid Use Disorder Crises Through Public-Private Partnerships

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Partnerships between public and private entities could expedite the development of nonaddictive pain therapies and other strategies to address the dual crises of chronic pain and opioid use disorder.

Education, Depression, Pain Associated With Opioid Misuse

Education, Depression, Pain Associated With Opioid Misuse

In adults age 50 or older, higher education, illicit drug use, depression, and pain interference with normal work are significantly associated with opioid misuse.

Parenteral Hydromorphone for Migraine and ED Revisits

Parenteral Hydromorphone for Migraine and ED Revisits

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Hydromorphone-related "likeability" and "feeling good" may not be associated with return visits to the emergency department in patients treated with the drug for migraine.

Pediatric ICU Admissions for Opioid Ingestion Continue to Rise

Pediatric ICU Admissions for Opioid Ingestion Continue to Rise

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In this retrospective analysis of the Pediatric Health Information System database, investigators obtained data on pediatric hospitalizations for opioid exposure in the US between 2004 and 2015.

Exparel Approved for Use as Interscalene Brachial Plexus Nerve Block

Exparel Approved for Use as Interscalene Brachial Plexus Nerve Block

Additionally, statistical significance vs placebo was also achieved in total postsurgical opioid consumption through 48 hours (P<0.0001); opioid-free subjects through 48 hours (P<0.01); and time to first opioid rescue through 48 hours (P<0.0001).

FDA: Social Media Companies Aren't Doing Enough to Stop Illegal Opioid Sales

FDA: Social Media Companies Aren't Doing Enough to Stop Illegal Opioid Sales

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A recent report from the U.S. Senate Permanent Subcommittee on Investigations detailed how subcommittee members found it 'easy' to find fentanyl, pay for it and have it shipped to anywhere in the U.S.

CDC: Overdose Deaths Up Across Drug Categories in 2015 to 2016

CDC: Overdose Deaths Up Across Drug Categories in 2015 to 2016

From 2015 to 2016, there were increases in deaths across all drug categories examined, with 63,632 drug overdose deaths in 2016.

Surgeon General Issues Advisory on Importance of Naloxone

Surgeon General Issues Advisory on Importance of Naloxone

In a statement released today, Surgeon General, Jerome M. Adams, MD, MPH, said, "It is time to make sure more people have access to this lifesaving medication, because 77 percent of opioid overdose deaths occur outside of a medical setting and more than half occur at home."

Case Report Reveals Another Possible Side Effect of Kratom

Case Report Reveals Another Possible Side Effect of Kratom

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According to the authors, this is the first report of kratom-induced hyperprolactinemia.

Provider Self-Perception of Opioid Prescribing Often Inaccurate, Says Study

Provider Self-Perception of Opioid Prescribing Often Inaccurate, Says Study

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Results showed that 65% of those in the intervention group underestimated their opioid prescribing.

Hydrocodone, Oxycodone Linked to Majority of Serious Opioid Adverse Event Cases

Hydrocodone, Oxycodone Linked to Majority of Serious Opioid Adverse Event Cases

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The 7 opioids included for analysis were oxycodone, hydrocodone, morphine, hydromorphone, oxymorphone, tapentadol, and tramadol.

Acute Pain Treatment in the ED: Consensus Guidelines

Acute Pain Treatment in the ED: Consensus Guidelines

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A panel of emergency medicine and pharmacology experts formulated guidelines for safely and effectively treating patients presenting to the emergency department with acute pain.

Pernix Announces Availability of Zohydro ER 20 mg Dosage Strength

Pernix Announces Availability of Zohydro ER 20 mg Dosage Strength

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Zohydro ER is also available in 10mg, 15mg, 30mg, 40mg, and 50mg dosage strengths.

Opioid Receipt Up for Teens With Mental Health Conditions

Opioid Receipt Up for Teens With Mental Health Conditions

Adolescents with pre-existing mental health conditions and treatments are more likely to receive any opioid and to transition to long-term opioid therapy.

Many Patients Receive Inappropriate Tests, Treatments for Low Back Pain

Many Patients Receive Inappropriate Tests, Treatments for Low Back Pain

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More emphasis should be placed on self-management, physical and psychological therapies for treating low back pain, rather than pharmacological or surgical treatments.

Opioids vs Nonopioid Medications for Chronic Back, Knee, and Hip Osteoarthritis Pain

Opioids vs Nonopioid Medications for Chronic Back, Knee, and Hip Osteoarthritis Pain

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Opioids and nonopioid analgesics were found to provide similar improvements in pain-related function over a 1-year period in patients with chronic back pain or knee or hip osteoarthritis pain.

Peripherally Acting Opioid and Cannabinoid May Be Effective for Neuropathic Pain

Peripherally Acting Opioid and Cannabinoid May Be Effective for Neuropathic Pain

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Cotargeting of peripheral μ-opioid and cannabinoid receptors was found to have a synergistic effect in reducing mechanical allodynia in a mouse model of neuropathic pain.

Too Early to Formulate Recommendations on Medical Cannabis vs Opioids for Pain?

Too Early to Formulate Recommendations on Medical Cannabis vs Opioids for Pain?

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Various strategies to reduce opioid overdose deaths have been implemented and it has been suggested that access to medical cannabis may lead to a reduction in opioid use for pain management.

Long-Term Opioid Use Increases Asthma, Allergic Rhinitis Prevalence

Long-Term Opioid Use Increases Asthma, Allergic Rhinitis Prevalence

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In addition to their analgesic effects, opioid binding to opioid receptors leads to the release of histamine from mast cells, including those implicated in asthma and allergic rhinitis.

Opioid vs Non-Opioid Treatment for Pain-Related Function

Opioid vs Non-Opioid Treatment for Pain-Related Function

The study compared opioid vs non-opioid treatment in 240 patients with either moderate to severe chronic back pain or hip or knee osteoarthritis pain.

Rates of Pediatric Hospitalization, ICU Admission Rise Due to Opioid Ingestion

Rates of Pediatric Hospitalization, ICU Admission Rise Due to Opioid Ingestion

Researchers assessed trends in the rate of pediatric intensive care unit admission for opioid-related ingestion over time using billing data from the Pediatric Health Information System .

Opioid Dependence Pharmacotherapy and Clinical, Criminal Outcomes in Mental Illness

Opioid Dependence Pharmacotherapy and Clinical, Criminal Outcomes in Mental Illness

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All 3 opioid-dependence pharmacotherapies — methadone, buprenorphine, and oral naltrexone — were associated with reductions in inpatient substance abuse treatment.

Medical Marijuana Laws, Dispensaries May Reduce Deaths From Opioid Overdose

Medical Marijuana Laws, Dispensaries May Reduce Deaths From Opioid Overdose

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Medical marijuana laws that include a "liberal" allowance of the drug to dispensaries may contribute to reducing opioid overdose-related deaths in Medicare Part-D and Medicaid beneficiaries.

Kratom-Containing Dietary Supplements Recalled

Kratom-Containing Dietary Supplements Recalled

The FDA said it wants all companies making kratom products to take them off the market, and urged all consumers who have kratom-containing products to stop using them and throw them away.

Benzhydrocodone/Acetaminophen Combination Gets FDA Approval for Severe Acute Pain

Benzhydrocodone/Acetaminophen Combination Gets FDA Approval for Severe Acute Pain

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The FDA has approved Apadaz for the short-term management of acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.

Antidepressant Medication Adherence and Long-Term Opioid Cessation

Antidepressant Medication Adherence and Long-Term Opioid Cessation

Antidepressant medication adherence is associated with cessation of long-term prescription opioid use among patients with non-cancer pain.

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