Intrathecal drug delivery systems may be ineffective in reducing pain and oral opioid intake in individuals with complex regional pain syndrome.
Utilization management strategies for opioid and nonopioid medications in low back pain, including quantity limits and prior authorization, were found to be commonly used in Medicaid, Medicare Advantage, and commercial insurance plans.
Mixing Sedative-Hypnotics, Prescription Opioids Associated With Suicidal Ideation in Serious Mental IllnessJuly 12, 2018
Concurrent use of sedative-hypnotic and prescription opioid medications may increase the risk for suicidal ideation in individuals with serious mental illness.
Parenteral Opioids May Be Effective for Reducing Pain During Childbirth According to Cochrane ReviewJuly 11, 2018
The use of parenteral opioid medications may be supported for effective pain relief during labor.
Women prescribed long- vs short-term opioids for chronic musculoskeletal pain may be at increased risk for menopause and abnormal menstruation.
Five-fold increased risk of opioid-related overdose during first 90 days of concurrent use
With the increasing number of patients presenting to surgery with opioid tolerance, clinicians should be familiar with their specific analgesic needs.
Dispositional mindfulness may help reduce the risk for opioid misuse in patients with chronic pain by attenuating opioid craving and directing attention to naturally rewarding stimuli.
Legislation that requires prescribers to check Ohio's Prescription Drug Monitoring Program was found to lead to a reduction in the quantity of opioids and benzodiazepines dispensed.
From 2001 to 2016 there was an increase in the number and percentage of opioid-related deaths; in addition, most patients receiving opioids receive immediate-release formulations.
Two lots of naloxone hydrochloride injections, USP have been recalled by Hospira, Inc., due to concerns regarding the presence of particulates on the syringe plunger.
A substantial proportion of these individuals diagnosed with HIV, psychiatric disorders, and substance use disorders are out of care and urgently require intervention.
Researchers proposed that future projects investigate the geographical and temporal trends in substance use and its disease burden.
Researchers used vital statistics data to examine whether increases in mortality rates and years of potential life lost among midlife non-Hispanic whites from 1999 to 2015 are associated with increases in fatal overdoses.
PA students perceived improved confidence in their ability to provide patient education and counseling.
Adverse events associated with opioids administered for the management of postsurgical and postendoscopy pain may be associated with worse cost and patient outcomes.
Opioid use was compared between a six-month control period and three months following education for prescribers on opioid administration routes, focusing on awareness of the subcutaneous routes.
Lucemyra, a selective alpha 2-adrenergic receptor agonist, works by reducing the release of norepinephrine and decreasing sympathetic tone.
Researchers examined the extent to which pharmaceutical industry marketing of opioid products to physicians during 2014 correlated with opioid prescribing in 2015.
The most common prescription drug in US adults with chronic low back pain are opioids.
Opioids were found to be associated with adverse events in older Medicare beneficiaries on hemodialysis.
The researchers found that the median prescription size was 350 mg oral morphine equivalents and median patient use was 225 mg oral morphine equivalents following open hiatal hernia repair.
Persistent pain — which is common in survivors of critical illnesses — may not be associated with opioid exposure during intensive care unit stay.
Investigators pooled data from 2 phase 3 placebo-controlled studies to evaluate the safety and efficacy of lofexidine for opioid withdrawal symptoms.
For states that currently limit new acute opioid prescription fills to <7 days, Walmart and Sam's Club pharmacies will follow that state law.
Evidence allowing us to assess the benefits of and risks associated with prescription drug monitoring programs is insufficient.
Methadone Maintenance Therapy Associated With Greater Access to Physician Care in HCV-Positive Drug UsersMay 07, 2018
The investigators suggest that enrollment in a methadone maintenance therapy program may be helpful in providing access to HCV care in people who inject drugs.
Researchers conducted a prospective survey of patients to investigate postoperative opioid use.
The researchers note that patients with chronic pain and those with mood disorders are more likely to receive opioid prescriptions and are also at greater risk for suicide.
Recent physician-prescribed opioids represent the main source of provenance of the drug in individuals age ≥65 years who misuse them.
Clinical Pain Advisor Articles
- Abuse-Deterrent Opioid Formulations: Barriers to Broader Use
- Women Frequently Prescribed High Doses of Opioids After Vaginal Delivery
- Notifications by PDMPs May Not Effectively Reduce Opioid Misuse
- Virtual Reality May Effectively Reduce Sensory, Affective, and Cognitive Pain During Labor
- Electroacupuncture May Help Reduce Opioid Use in Chronic Musculoskeletal Pain
- Neuropathic Pain Medications
- Higher Buprenorphine Dose May Not Increase Severity of Neonatal Abstinence Syndrome
- Terms Used for Addiction May Be Associated With Explicit, Implicit Bias
- Ketamine Infusions May Be Effective for Refractory Headache
- Physical, Psychosocial Activity May Be Protective Against Development of Chronic Pain in Older Adults
- Opioid Use Disorder Prevalence at Delivery on the Rise in the US, According to CDC
- Suprazygomatic Sphenopalatine Ganglion Block May Quickly Relieve Status Migrainosus Pain
- Pharmacologically Induced Headache Accompanied by Dilated Cephalic Vessels
- IV Lidocaine May Be Safe, Efficacious for Pediatric Status Migraine
- Gray Matter Changes in Migraine Associated With Clinical Characteristics