Opioids

Pediatric Opioid Prescriptions Have Declined Since 2012

Pediatric Opioid Prescriptions Have Declined Since 2012

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After increasing for several years, pediatric opioid prescriptions have been decreasing since 2012 in the United States.

Intrathecal Drug Delivery Systems May Be Ineffective for Complex Regional Pain Syndrome

Intrathecal Drug Delivery Systems May Be Ineffective for Complex Regional Pain Syndrome

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Intrathecal drug delivery systems may be ineffective in reducing pain and oral opioid intake in individuals with complex regional pain syndrome.

Opioid, Nonopioid Utilization Management for Low Back Pain Prevalent in Major Health Plans

Opioid, Nonopioid Utilization Management for Low Back Pain Prevalent in Major Health Plans

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Utilization management strategies for opioid and nonopioid medications in low back pain, including quantity limits and prior authorization, were found to be commonly used in Medicaid, Medicare Advantage, and commercial insurance plans.

Opioid Users More Likely to Have Complex Health Issues and Dealings With Criminal Justice System

Opioid Users More Likely to Have Complex Health Issues and Dealings With Criminal Justice System

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Individuals taking opioids were found to be more likely to report physical and mental health issues and to have more frequent dealings with the criminal justice system compared with individuals not taking opioids.

Debunking Myths Around Treatment for Opioid Use Disorder

Debunking Myths Around Treatment for Opioid Use Disorder

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Primary care office-based addiction treatment of opioid use disorder with buprenorphine is a realistic and scalable solution to address the overdose crisis in the United States.

Postpartum Pain Management Recommendations From the American College of Obstetricians and Gynecologists

Postpartum Pain Management Recommendations From the American College of Obstetricians and Gynecologists

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A committee from the American College of Obstetricians and Gynecologists formulated several recommendations for safely managing pain and fatigue in women during the early postpartum period.

Methadone Improves Short-Term Outcomes Better Than Morphine in Neonatal Abstinence Syndrome

Methadone Improves Short-Term Outcomes Better Than Morphine in Neonatal Abstinence Syndrome

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Methadone may be superior to morphine for reducing hospital length of stay and length of drug treatment in infants with neonatal abstinence syndrome.

Optimal Strategies for Opioid Weaning After Ambulatory Surgery

Optimal Strategies for Opioid Weaning After Ambulatory Surgery

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Although there is a scarcity of evidence pertaining to the management of postoperative pain medication in the ambulatory setting, some findings suggest an approach similar to that used for the treatment of acute pain.

Emergency Physicians Offer Recommendations for Identifying and Managing Opioid Use Disorder

Emergency Physicians Offer Recommendations for Identifying and Managing Opioid Use Disorder

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American emergency medicine physicians have been taking measures to address the ongoing opioid crisis, which affects emergency departments throughout the country.

Mixing Sedative-Hypnotics, Prescription Opioids Associated With Suicidal Ideation in Serious Mental Illness

Mixing Sedative-Hypnotics, Prescription Opioids Associated With Suicidal Ideation in Serious Mental Illness

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Concurrent use of sedative-hypnotic and prescription opioid medications may increase the risk for suicidal ideation in individuals with serious mental illness.

Parenteral Opioids May Be Effective for Reducing Pain During Childbirth According to Cochrane Review

Parenteral Opioids May Be Effective for Reducing Pain During Childbirth According to Cochrane Review

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The use of parenteral opioid medications may be supported for effective pain relief during labor.

FDA Takes Steps to Reconcile Needs of Patients With Chronic Pain, Efforts to Curb Opioid Epidemic

FDA Takes Steps to Reconcile Needs of Patients With Chronic Pain, Efforts to Curb Opioid Epidemic

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A panel discussion event held at the US Food and Drug Administration gathered patients with chronic pain and FDA officials, to reconcile concerns around prescriptions of opioid medications with the needs of these patient populations.

Reproductive Dysfunction Risk in Women Taking Long-Term Opioids for Musculoskeletal Pain

Reproductive Dysfunction Risk in Women Taking Long-Term Opioids for Musculoskeletal Pain

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Women prescribed long- vs short-term opioids for chronic musculoskeletal pain may be at increased risk for menopause and abnormal menstruation.

Lofexidine a Non-Narcotic Option for Opioid Withdrawal Symptoms

Lofexidine a Non-Narcotic Option for Opioid Withdrawal Symptoms

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Lofexidine may help patients with opioid withdrawal symptoms or difficulty with opioid discontinuation.

Overdose Risk Highest in First Days of Concurrent Opioid, Benzodiazepine Use

Overdose Risk Highest in First Days of Concurrent Opioid, Benzodiazepine Use

Five-fold increased risk of opioid-related overdose during first 90 days of concurrent use

Chronic Pain Leads to Higher Opioid Doses and Lower QoL in Sickle Cell Patients

Chronic Pain Leads to Higher Opioid Doses and Lower QoL in Sickle Cell Patients

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In adults with sickle cell disease, higher daily opioid use may be associated with poorer health-related quality of life.

Prescribing Patterns in Emergency Department May Be Affected by Race, Sex

Prescribing Patterns in Emergency Department May Be Affected by Race, Sex

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Patients' race/ethnicity and sex may have an effect on prescribing patterns for opioid and nonopioid medications.

Opioid-Related Adverse Events Common After Invasive Procedures

Opioid-Related Adverse Events Common After Invasive Procedures

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For patients undergoing invasive procedures, opioid-related adverse drug events are common and are associated with worse clinical and cost outcomes.

Opioid-Free Analgesia Use for Postsurgical Pain Limited

Opioid-Free Analgesia Use for Postsurgical Pain Limited

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The use of opioid-free analgesia to manage postsurgical pain is still limited, particularly in some patient groups that may be at a higher risk for opioid-related adverse drug events.

Targeted Educational Intervention Helped Reduce Opioid Exposure in Adult Inpatients

Targeted Educational Intervention Helped Reduce Opioid Exposure in Adult Inpatients

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A targeted intervention strategy aimed at decreasing intravenous opioid use in hospitalized adults was found to lower both intravenous and overall parenteral opioid prescriptions.

First Generic Versions of Suboxone Get FDA Approval for Opioid Dependence

First Generic Versions of Suboxone Get FDA Approval for Opioid Dependence

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The treatment combines buprenorphine, a partial-opioid agonist, with naloxone, an opioid antagonist.

Recommendations for Perioperative Pain Management in Patients With Opioid Tolerance

Recommendations for Perioperative Pain Management in Patients With Opioid Tolerance

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With the increasing number of patients presenting to surgery with opioid tolerance, clinicians should be familiar with their specific analgesic needs.

Dispositional Mindfulness May Reduce Opioid Misuse in Chronic Pain

Dispositional Mindfulness May Reduce Opioid Misuse in Chronic Pain

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Dispositional mindfulness may help reduce the risk for opioid misuse in patients with chronic pain by attenuating opioid craving and directing attention to naturally rewarding stimuli.

Mandatory PDMP for Prescribers Lowers Opioid Dispensing Rate

Mandatory PDMP for Prescribers Lowers Opioid Dispensing Rate

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Legislation that requires prescribers to check Ohio's Prescription Drug Monitoring Program was found to lead to a reduction in the quantity of opioids and benzodiazepines dispensed.

Studies ID Impact of U.S. Opioid-Related Mortality, Rx Patterns

Studies ID Impact of U.S. Opioid-Related Mortality, Rx Patterns

From 2001 to 2016 there was an increase in the number and percentage of opioid-related deaths; in addition, most patients receiving opioids receive immediate-release formulations.

NDA for First-of-Its-Kind Opioid Analgesic Submitted to FDA

NDA for First-of-Its-Kind Opioid Analgesic Submitted to FDA

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NKTR-181 is a long-acting selective full mu-opioid agonist.

Two Lots of Naloxone Hydrochloride Carpuject Injections Recalled

Two Lots of Naloxone Hydrochloride Carpuject Injections Recalled

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Two lots of naloxone hydrochloride injections, USP have been recalled by Hospira, Inc., due to concerns regarding the presence of particulates on the syringe plunger.

HIV Viral Suppression Rates in Psychiatric Inpatients With Comorbid Substance Use Disorders

HIV Viral Suppression Rates in Psychiatric Inpatients With Comorbid Substance Use Disorders

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A substantial proportion of these individuals diagnosed with HIV, psychiatric disorders, and substance use disorders are out of care and urgently require intervention.

Global Prevalence of Alcohol, Tobacco, and Illicit Drug Use: A 2017 Status Report

Global Prevalence of Alcohol, Tobacco, and Illicit Drug Use: A 2017 Status Report

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Researchers proposed that future projects investigate the geographical and temporal trends in substance use and its disease burden.

Association Between Industry Payments and Opioid Prescribing

Association Between Industry Payments and Opioid Prescribing

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Non-research industry payments to physicians may be associated with increases in opioid prescribing rates.

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