Individuals with and without cancer may be affected in a similar manner by concerns surrounding opioids that have led to reductions in their prescribing.
Postoperative pain management that combines a reduction of opioids with the use of intravenous acetaminophen may shorten hospital length of stay, reduce the rate of complications related to opioids, and lower related costs.
Katie Burk, MPH, presented measures undertaken by the city of San Francisco to provide integrated responses to the concurrent HIV/HCV and opioid public health epidemics.
Package inserts of opioid analgesics may not consistently provide information regarding safe drug storage and/or disposal.
Partnerships between public and private entities could expedite the development of nonaddictive pain therapies and other strategies to address the dual crises of chronic pain and opioid use disorder.
In adults age 50 or older, higher education, illicit drug use, depression, and pain interference with normal work are significantly associated with opioid misuse.
Hydromorphone-related "likeability" and "feeling good" may not be associated with return visits to the emergency department in patients treated with the drug for migraine.
In this retrospective analysis of the Pediatric Health Information System database, investigators obtained data on pediatric hospitalizations for opioid exposure in the US between 2004 and 2015.
Additionally, statistical significance vs placebo was also achieved in total postsurgical opioid consumption through 48 hours (P<0.0001); opioid-free subjects through 48 hours (P<0.01); and time to first opioid rescue through 48 hours (P<0.0001).
A recent report from the U.S. Senate Permanent Subcommittee on Investigations detailed how subcommittee members found it 'easy' to find fentanyl, pay for it and have it shipped to anywhere in the U.S.
From 2015 to 2016, there were increases in deaths across all drug categories examined, with 63,632 drug overdose deaths in 2016.
In a statement released today, Surgeon General, Jerome M. Adams, MD, MPH, said, "It is time to make sure more people have access to this lifesaving medication, because 77 percent of opioid overdose deaths occur outside of a medical setting and more than half occur at home."
According to the authors, this is the first report of kratom-induced hyperprolactinemia.
Results showed that 65% of those in the intervention group underestimated their opioid prescribing.
The 7 opioids included for analysis were oxycodone, hydrocodone, morphine, hydromorphone, oxymorphone, tapentadol, and tramadol.
A panel of emergency medicine and pharmacology experts formulated guidelines for safely and effectively treating patients presenting to the emergency department with acute pain.
Zohydro ER is also available in 10mg, 15mg, 30mg, 40mg, and 50mg dosage strengths.
Adolescents with pre-existing mental health conditions and treatments are more likely to receive any opioid and to transition to long-term opioid therapy.
More emphasis should be placed on self-management, physical and psychological therapies for treating low back pain, rather than pharmacological or surgical treatments.
Opioids and nonopioid analgesics were found to provide similar improvements in pain-related function over a 1-year period in patients with chronic back pain or knee or hip osteoarthritis pain.
Cotargeting of peripheral μ-opioid and cannabinoid receptors was found to have a synergistic effect in reducing mechanical allodynia in a mouse model of neuropathic pain.
Various strategies to reduce opioid overdose deaths have been implemented and it has been suggested that access to medical cannabis may lead to a reduction in opioid use for pain management.
In addition to their analgesic effects, opioid binding to opioid receptors leads to the release of histamine from mast cells, including those implicated in asthma and allergic rhinitis.
The study compared opioid vs non-opioid treatment in 240 patients with either moderate to severe chronic back pain or hip or knee osteoarthritis pain.
Researchers assessed trends in the rate of pediatric intensive care unit admission for opioid-related ingestion over time using billing data from the Pediatric Health Information System .
All 3 opioid-dependence pharmacotherapies — methadone, buprenorphine, and oral naltrexone — were associated with reductions in inpatient substance abuse treatment.
Medical marijuana laws that include a "liberal" allowance of the drug to dispensaries may contribute to reducing opioid overdose-related deaths in Medicare Part-D and Medicaid beneficiaries.
The FDA said it wants all companies making kratom products to take them off the market, and urged all consumers who have kratom-containing products to stop using them and throw them away.
The FDA has approved Apadaz for the short-term management of acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.
Antidepressant medication adherence is associated with cessation of long-term prescription opioid use among patients with non-cancer pain.
Clinical Pain Advisor Articles
- Reviewing the Efficacy, Safety, and Tolerability of Cannabis-Based Medicines for Chronic Neuropathic Pain
- Femoral Nerve Block Alone or in Combination With Sciatic Nerve Block for TKA: A Meta-Analysis
- Tackling the Chronic Pain and Opioid Use Disorder Crises Through Public-Private Partnerships
- How the City of San Francisco Is Tackling the Intertwined HIV/HCV and Opioid Epidemics
- The State of Drug Storage, Disposal Labeling Information for Opioid Analgesics
- Radiofrequency Ablation for Chronic Hip Pain: Reviewing the Evidence
- Opioid Use Disorder Treatment: Evidence-Based Guideline
- Betel Quid Addiction and Implications for Substance Use Disorder
- Low Back Pain: Contributing Factors, Prophylactic Strategies, and Effective Treatments
- Exparel Approved for Use as Interscalene Brachial Plexus Nerve Block
- Transcranial Magnetic Stimulation May Prevent Migraine in Adolescents
- Widespread Impact of Reducing Opioids, Adding IV Acetaminophen for Postsurgical Pain Management
- GI Safety Compared for NSAIDs in Patients With Arthritis
- Opioid Prescribing Trends in Patients With, Without Cancer
- DOJ Rescinds Protections Afforded by Americans With Disabilities Act