Naldemedine was found to be safe and effective for increasing bowel movement frequency and improving quality of life in patients with chronic non-cancer pain and opioid-induced constipation.
The use of oxycodone/naloxone prolonged-release tablets (OXN PR) can provide significant relief for patients who suffer from moderate to severe chronic pain and opioid-induced constipation.
Naloxegol was shown to maintain adequate opioid analgesia over a 12-week treatment course, while relieving opioid-induced constipation.
In patients with opioid-induced constipation, naldemedine was shown to improve patient assessment of symptoms and quality of life.
A daily subcutaneous injection of methylnaltrexone provides effective relief from opioid-induced constipation in patients with chronic non-cancer pain.
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