Identification of Active-State Kappa-Opioid Receptor Crystal Structure May Facilitate the Design of Improved AnalgesicsJanuary 18, 2018
Elucidation of the crystal structure of κ-opioid receptors in their active state may facilitate the design of optimized analgesics, devoid of psychoactive effects and of addictive properties.
Preoperative opioid use is a better predictor for prolonged postoperative opioid use than pain, substance abuse, and affective disorder.
Much of the third world is suffering in pain without access to opioids. This imbalance has been called the opioid gap. How can we get opioids to patients who need them?
Clinical Pain Advisor Articles
- Supervised Injection Sites: Facts, Information, Pros, and Cons
- Chronic Pain May Be a Contributing Factor to Suicide
- Striking a Balance Between Opioid Surveillance and Patient Privacy
- Demographic Characteristics of Pregnant Women With Opioid Use Disorder
- Effects of Mindfulness Therapy, Pharmacologic Prophylaxis on Catecholamine Levels in Migraine
- Perioperative Pain Management in Patients With Opioid Use Disorder
- Cannabinoid-Associated Analgesia May Be Mediated Through Modulation of Affective Processes
- Seven-Item Pain Intensity Measure Reliable in Individuals With Dementia
- Reviewing the Efficacy of Invasive Procedures for Chronic Back, Knee Pain
- Antidepressant Effects of Ketamine Appear to Require Opioid System Activation
- Lower Weighting of Hand Cortical Representations in CRPS
- Predicting Success of Focal Nerve Surgery Based on Diagnostic Block Response
- Aetna-CVS Merger Approved
- FDA Announces Draft Guidance for Consumer OTC Access to Previously Prescription Drugs
- Maryland Legislature: Will Federal Courts Permit State Regulation of Drug Prices?