Opioid Addiction

Rapid Decrease of Heroin Use During Opioid Substitution Treatment Associated With Treatment Success

Rapid Decrease of Heroin Use During Opioid Substitution Treatment Associated With Treatment Success

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In patients receiving opioid substitution treatment for opioid use disorder (mainly involving heroin), those exhibiting a rapid decline in heroin use were found to be more likely to have successful treatment outcomes.

Wearable Device Cleared for Use During Opioid Detoxification

Wearable Device Cleared for Use During Opioid Detoxification

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Electrical pulses are sent through small needles that are inserted in the ear to combat the early stages of detoxification, leading to stabilization.

Public Support Only Moderate for Opioid Harm Reduction Strategies

Public Support Only Moderate for Opioid Harm Reduction Strategies

Shame to those who use opioids are based on more evidence than what society perceives.

CDC Report: Integrating Tobacco Cessation Interventions in Mental Health, Substance Abuse Treatment Facilities

CDC Report: Integrating Tobacco Cessation Interventions in Mental Health, Substance Abuse Treatment Facilities

Providing barrier-free access to proven cessation treatments is critical to reduce smoking-related disease and death in the United States.

Recommendations for Perioperative Pain Management in Patients With Opioid Tolerance

Recommendations for Perioperative Pain Management in Patients With Opioid Tolerance

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With the increasing number of patients presenting to surgery with opioid tolerance, clinicians should be familiar with their specific analgesic needs.

Court-Mandated Substance Abuse Treatment: Exploring the Ethics and Efficacy

Court-Mandated Substance Abuse Treatment: Exploring the Ethics and Efficacy

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While many treatments for substance use disorder are not evidence based, several evidence-based approaches have shown effectiveness in court-mandated treatment settings.

Mandatory PDMP for Prescribers Lowers Opioid Dispensing Rate

Mandatory PDMP for Prescribers Lowers Opioid Dispensing Rate

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Legislation that requires prescribers to check Ohio's Prescription Drug Monitoring Program was found to lead to a reduction in the quantity of opioids and benzodiazepines dispensed.

FDA Cracks Down on Illegal Online Sales of Opioids

FDA Cracks Down on Illegal Online Sales of Opioids

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The U.S. Food and Drug Administration has issued warnings to 9 online companies selling illegal opioid medications on 53 websites, in direct violation of the Federal Food, Drug, and Cosmetic Act.

Studies ID Impact of U.S. Opioid-Related Mortality, Rx Patterns

Studies ID Impact of U.S. Opioid-Related Mortality, Rx Patterns

From 2001 to 2016 there was an increase in the number and percentage of opioid-related deaths; in addition, most patients receiving opioids receive immediate-release formulations.

NDA for First-of-Its-Kind Opioid Analgesic Submitted to FDA

NDA for First-of-Its-Kind Opioid Analgesic Submitted to FDA

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NKTR-181 is a long-acting selective full mu-opioid agonist.

Substance Abuse and Primary Psychosis: A Closer Look

Substance Abuse and Primary Psychosis: A Closer Look

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Patients will still be at risk for schizophrenia or bipolar disorder even several years after an episode of substance-induced psychosis.

Opioid Epidemic Associated With Increase in Recovery of Organs for Transplantation

Opioid Epidemic Associated With Increase in Recovery of Organs for Transplantation

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The number of transplants of organs from brain-dead donors has risen sharply in the United States, primarily due to the increase in mortality associated with the drug-abuse epidemic.

Two Lots of Naloxone Hydrochloride Carpuject Injections Recalled

Two Lots of Naloxone Hydrochloride Carpuject Injections Recalled

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Two lots of naloxone hydrochloride injections, USP have been recalled by Hospira, Inc., due to concerns regarding the presence of particulates on the syringe plunger.

Increases in Acute HCV Infection, Injection Drug Use, and the Opioid Epidemic

Increases in Acute HCV Infection, Injection Drug Use, and the Opioid Epidemic

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Investigators compared rates of opioid injection drug use with the incidence of acute HCV infection in the United States.

Years of Life Lost and Fatal Drug Overdoses

Years of Life Lost and Fatal Drug Overdoses

Researchers used vital statistics data to examine whether increases in mortality rates and years of potential life lost among midlife non-Hispanic whites from 1999 to 2015 are associated with increases in fatal overdoses.

Factors Associated With ER-Naltrexone Treatment Success

Factors Associated With ER-Naltrexone Treatment Success

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Mental health, education level, and recent drug use may be associated with duration of treatment with extended-release naltrexone for opioid dependence.

Patterns of Potential Misuse Help Assess Risk of Opioid Overdose

Patterns of Potential Misuse Help Assess Risk of Opioid Overdose

Researchers estimated how a range of patterns of potential opioid misuse relate to adverse outcomes during the next year.

Opioid Education Program Boosts PA Students' Confidence in Providing Patient Care

Opioid Education Program Boosts PA Students' Confidence in Providing Patient Care

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PA students perceived improved confidence in their ability to provide patient education and counseling.

Unit-Dose Packaging of Buprenorphine-Naloxone Effective on Unintentional Pediatric Exposure

Unit-Dose Packaging of Buprenorphine-Naloxone Effective on Unintentional Pediatric Exposure

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Unit-dose packaging of buprenorphine-naloxone was associated with a reduced number of unintentional exposures of young children presenting to poison centers.

Detox vs Medication-Assisted Treatment for Opioid Use Disorder in Pregnancy: Expert Roundtable

Detox vs Medication-Assisted Treatment for Opioid Use Disorder in Pregnancy: Expert Roundtable

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Based on current evidence, there is a strong consensus that medication-assisted treatment is recommended over detoxification in the treatment of opioid use disorder during pregnancy.

Naloxone Training Beneficial for PA Students

Naloxone Training Beneficial for PA Students

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Opioid-specific health seminars may help PA students learn lifesaving treatments to perform in the future.

Many Have Unused Opioids After Urologic Procedures

Many Have Unused Opioids After Urologic Procedures

Patients undergoing urological procedures use just over half of their initial prescription of opioids, on average.

Supervised Injection Sites Hailed as the Latest Strategy to Fight the Opioid Crisis

Supervised Injection Sites Hailed as the Latest Strategy to Fight the Opioid Crisis

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Although they are against the law, supervised injection sites are slated to open in Seattle, San Francisco, and Philadelphia in 2018.

First Non-Opioid Drug Approved for Managing Opioid Withdrawal Symptoms

First Non-Opioid Drug Approved for Managing Opioid Withdrawal Symptoms

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Lucemyra, a selective alpha 2-adrenergic receptor agonist, works by reducing the release of norepinephrine and decreasing sympathetic tone.

Opioid-Related Payments Linked to Increase in Opioid Prescriptions

Opioid-Related Payments Linked to Increase in Opioid Prescriptions

Researchers examined the extent to which pharmaceutical industry marketing of opioid products to physicians during 2014 correlated with opioid prescribing in 2015.

Lofexidine Effective for Opioid Withdrawal Symptoms

Lofexidine Effective for Opioid Withdrawal Symptoms

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Investigators pooled data from 2 phase 3 placebo-controlled studies to evaluate the safety and efficacy of lofexidine for opioid withdrawal symptoms.

Walmart Plans on Restricting Supply on Acute Opioid Prescription Fills

Walmart Plans on Restricting Supply on Acute Opioid Prescription Fills

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For states that currently limit new acute opioid prescription fills to <7 days, Walmart and Sam's Club pharmacies will follow that state law.

Methadone Maintenance Therapy Associated With Greater Access to Physician Care in HCV-Positive Drug Users

Methadone Maintenance Therapy Associated With Greater Access to Physician Care in HCV-Positive Drug Users

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The investigators suggest that enrollment in a methadone maintenance therapy program may be helpful in providing access to HCV care in people who inject drugs.

People With Opioid Use Disorder Have High Suicide Rate

People With Opioid Use Disorder Have High Suicide Rate

The researchers note that patients with chronic pain and those with mood disorders are more likely to receive opioid prescriptions and are also at greater risk for suicide.

Contribution of Synthetic Opioids to Drug Overdose Deaths

Contribution of Synthetic Opioids to Drug Overdose Deaths

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Opioids were the leading contributor to drug overdose deaths between 2015 and 2016.

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