Opioid Addiction
Notifications by PDMPs May Not Effectively Reduce Opioid Misuse
August 10, 2018Unsolicited notices to prescribers as part of prescription drug monitoring programs may not effectively reduce opioid use, as patients may seek other prescribers.
Abuse-Deterrent Opioid Formulations: Barriers to Broader Use
August 09, 2018Abuse-deterrent opioid formulations have not yet been widely accepted despite their proposed value in reducing opioid abuse and related mortality. Many of the current barriers to broader use are related to their higher cost compared with conventional formulations.
Integrating Treatments for Opioid Use Disorder and Infectious Diseases
August 09, 2018All healthcare providers have a role in combating the opioid use disorder epidemic and its infectious disease consequences.
Which Opioids Are More Likely to Induce QT Interval Prolongation?
August 08, 2018Studies comparing MMT to buprenorphine maintenance treatment (BMT) over 5-years found buprenorphine to be a safer drug for opioid maintenance treatment as it had no significant effect on QT prolongation.
Assessing Medication-Assisted Treatments: FDA Guidance for Drug Developers
August 07, 2018In a communiqué issued on August 6, 2018, the US Food and Drug Administration announced the release of a draft guidance titled, "Opioid Use Disorder: Endpoints for Demonstrating Effectiveness of Drugs for Medication-Assisted Treatment - Guidance for Industry."
Opioid Use Disorders: Advances in Pharmacotherapy Provide Long-term Results
August 07, 2018Despite the availability of long-acting opioid antagonists, many patients with OUD never receive adequate treatment.
Lucemyra Now Available for Mitigation of Opioid Withdrawal Symptoms
August 07, 2018Lucemyra is not indicated as a treatment for opioid use disorder.
Medicaid Expansion Under ACA Found to Benefit Access to Treatments for Opioid Use Disorder
August 06, 2018States that have adopted Medicaid expansions under the Affordable Care Act saw an increase in the utilization and availability of treatments for opioid use disorder.
Therapy Focusing on Mindfulness Improves Outcomes for Women With Substance Use Disorder
July 30, 2018These findings are consistent with emerging neurocognitive models linking interoception to emotion regulation and related health outcomes, providing valuable input in improving substance use disorder treatment.
Debunking Myths Around Treatment for Opioid Use Disorder
July 30, 2018Primary care office-based addiction treatment of opioid use disorder with buprenorphine is a realistic and scalable solution to address the overdose crisis in the United States.
Distress Tolerance Associated With Alcohol Use in Women With Opioid Use Disorder
July 27, 2018In women with opioid use disorder, greater distress tolerance may be associated with fewer alcohol use days.
Higher Buprenorphine Dose May Not Increase Severity of Neonatal Abstinence Syndrome
July 26, 2018Pregnant women receiving medication therapy for addiction can be prescribed higher doses of buprenorphine without increasing the risk or severity of neonatal abstinence syndrome.
Preoperative Opioids Used by Nearly One-Quarter of Surgical Patients
July 24, 2018Preoperative opioid use is reported in 23.1 percent of patients undergoing surgery.
Prescribed Opioids Difficulties Scale Effective for Assessing Concerns of Patients With Chronic Pain
July 18, 2018The Prescribed Opioids Difficulties Scale may be effective for identifying patients using opioids for chronic noncancer pain who are worried about their usage.
NIH Initiative Aims to Address Opioid Misuse Over Long Term
June 26, 2018A novel, innovative initiative is being developed to help end addiction over the long term, according to a viewpoint article published online June 12 in the Journal of the American Medical Association.
Rapid Decrease of Heroin Use During Opioid Substitution Treatment Associated With Treatment Success
June 19, 2018In patients receiving opioid substitution treatment for opioid use disorder (mainly involving heroin), those exhibiting a rapid decline in heroin use were found to be more likely to have successful treatment outcomes.
Wearable Device Cleared for Use During Opioid Detoxification
June 15, 2018Electrical pulses are sent through small needles that are inserted in the ear to combat the early stages of detoxification, leading to stabilization.
Public Support Only Moderate for Opioid Harm Reduction Strategies
June 14, 2018Shame to those who use opioids are based on more evidence than what society perceives.
CDC Report: Integrating Tobacco Cessation Interventions in Mental Health, Substance Abuse Treatment Facilities
June 14, 2018Providing barrier-free access to proven cessation treatments is critical to reduce smoking-related disease and death in the United States.
Recommendations for Perioperative Pain Management in Patients With Opioid Tolerance
June 12, 2018With the increasing number of patients presenting to surgery with opioid tolerance, clinicians should be familiar with their specific analgesic needs.
Court-Mandated Substance Abuse Treatment: Exploring the Ethics and Efficacy
June 06, 2018While many treatments for substance use disorder are not evidence based, several evidence-based approaches have shown effectiveness in court-mandated treatment settings.
Mandatory PDMP for Prescribers Lowers Opioid Dispensing Rate
June 06, 2018Legislation that requires prescribers to check Ohio's Prescription Drug Monitoring Program was found to lead to a reduction in the quantity of opioids and benzodiazepines dispensed.
FDA Cracks Down on Illegal Online Sales of Opioids
June 06, 2018The U.S. Food and Drug Administration has issued warnings to 9 online companies selling illegal opioid medications on 53 websites, in direct violation of the Federal Food, Drug, and Cosmetic Act.
Studies ID Impact of U.S. Opioid-Related Mortality, Rx Patterns
June 05, 2018From 2001 to 2016 there was an increase in the number and percentage of opioid-related deaths; in addition, most patients receiving opioids receive immediate-release formulations.
NDA for First-of-Its-Kind Opioid Analgesic Submitted to FDA
June 05, 2018NKTR-181 is a long-acting selective full mu-opioid agonist.
Substance Abuse and Primary Psychosis: A Closer Look
June 04, 2018Patients will still be at risk for schizophrenia or bipolar disorder even several years after an episode of substance-induced psychosis.
Opioid Epidemic Associated With Increase in Recovery of Organs for Transplantation
June 04, 2018The number of transplants of organs from brain-dead donors has risen sharply in the United States, primarily due to the increase in mortality associated with the drug-abuse epidemic.
Two Lots of Naloxone Hydrochloride Carpuject Injections Recalled
June 04, 2018Two lots of naloxone hydrochloride injections, USP have been recalled by Hospira, Inc., due to concerns regarding the presence of particulates on the syringe plunger.
Increases in Acute HCV Infection, Injection Drug Use, and the Opioid Epidemic
June 01, 2018Investigators compared rates of opioid injection drug use with the incidence of acute HCV infection in the United States.
Years of Life Lost and Fatal Drug Overdoses
May 29, 2018Researchers used vital statistics data to examine whether increases in mortality rates and years of potential life lost among midlife non-Hispanic whites from 1999 to 2015 are associated with increases in fatal overdoses.
Clinical Pain Advisor Articles
- Opioid Use Disorders: Advances in Pharmacotherapy Provide Long-term Results
- Abuse-Deterrent Opioid Formulations: Barriers to Broader Use
- Women Frequently Prescribed High Doses of Opioids After Vaginal Delivery
- Notifications by PDMPs May Not Effectively Reduce Opioid Misuse
- Virtual Reality May Effectively Reduce Sensory, Affective, and Cognitive Pain During Labor
- Neuropathic Pain Medications
- Higher Buprenorphine Dose May Not Increase Severity of Neonatal Abstinence Syndrome
- Terms Used for Addiction May Be Associated With Explicit, Implicit Bias
- Ketamine Infusions May Be Effective for Refractory Headache
- Physical, Psychosocial Activity May Be Protective Against Development of Chronic Pain in Older Adults
- Prioritizing Rest in Hospital Settings: Poor Sleep Increases Costs, Complications, and Mortality
- Pain Catastrophizing Decreases in Rheumatoid Arthritis After DMARD Initiation
- Addressing Commercial Incentives in the Medical Device Industry
- Cancer Patients Treated With Step III Opioids Often Have Sleep Disturbances
- Low Literacy Self-Management Program for Chronic Pain May Be Effective
