Opioid Addiction

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Staying in Line With Medical Ethics by Altering Opioid Prescribing Practices

Staying in Line With Medical Ethics by Altering Opioid Prescribing Practices

One physician shares his thoughts on the importance of balancing autonomy, beneficence, and nonmaleficence when prescribing opioids to patients.

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Guidelines on the Perioperative Pain Management of Patients on Buprenorphine Therapy

Guidelines on the Perioperative Pain Management of Patients on Buprenorphine Therapy

Clinical best practice recommendations for the use of buprenorphine in the perioperative management of patients undergoing interventional pain procedures and other surgeries were recently published.

Antidepressant Medication Adherence and Long-Term Opioid Cessation

Antidepressant Medication Adherence and Long-Term Opioid Cessation

Antidepressant medication adherence is associated with cessation of long-term prescription opioid use among patients with non-cancer pain.

American Psychiatric Association Proposes DSM-5 Coding Change for Opioid Withdrawal

American Psychiatric Association Proposes DSM-5 Coding Change for Opioid Withdrawal

The proposal addresses inappropriate ICD-10-CM coding options for withdrawal from opioids, sedatives, or stimulants.

Comparing the Efficacy of Extended-Release Naltrexone and Buprenorphine-Naloxone on Opioid Relapse

Comparing the Efficacy of Extended-Release Naltrexone and Buprenorphine-Naloxone on Opioid Relapse

Extended-release naltrexone and sublingual buprenorphine-naloxone were equally effective for preventing opioid abuse relapse.

FDA Concerned About Potential for Abuse, Addiction With Kratom

FDA Concerned About Potential for Abuse, Addiction With Kratom

An investigation of the 25 most prevalent compounds in kratom showed that these compounds share structural similarities with controlled opioid analgesics, such as morphine derivatives.

Opioid Use in Sepsis Linked to Higher Mortality

Opioid Use in Sepsis Linked to Higher Mortality

Higher mortality associated with opioid use in hospitalized patients with sepsis suggests an immunosuppressive effect that could contribute to worse outcomes.

Opioid Prescribing Trends in the Veterans Health Administration

Opioid Prescribing Trends in the Veterans Health Administration

Opioid prescribing trends in the Veterans Health Administration from 2010 to 2016 followed similar trajectories as non-VHA settings, peaking around 2012 then declining.

Opioid Prescriptions After Surgery: Parameters to Blame for Misuse

Opioid Prescriptions After Surgery: Parameters to Blame for Misuse

Prescription opioid duration — not dosage — following surgery may be associated with a greater risk for opioid misuse in patients with no prior history of opioid use.

Evaluating Excessive NSAID Use in Ibuprofen Users

Evaluating Excessive NSAID Use in Ibuprofen Users

Fifteen percent of adults who took ibuprofen during a 1-week diary study exceeded the maximum recommended daily dose limit.

Tamper-Resistant Controlled-Release Oxycodone and Opioid Use: A Population Study

Tamper-Resistant Controlled-Release Oxycodone and Opioid Use: A Population Study

A new tamper-resistant formulation of controlled-release oxycodone was not found to reduce opioid use or harm at the population level.

Electronic Medical Record "Nudge" May Shape Opioid Prescribing Behavior in the ED

Electronic Medical Record "Nudge" May Shape Opioid Prescribing Behavior in the ED

Implementation of electronic medical record default opioid prescriptions of 10 tablets of 5 mg oxycodone/325 mg acetaminophen at discharge from the ED may be associated with an increased percentage of prescriptions for 10 tablets, compared with no default.

Walmart Launching Disposal Program for Opioids, Leftover Prescription Drugs

Walmart Launching Disposal Program for Opioids, Leftover Prescription Drugs

Walmart is launching a first-of-its-kind opioid disposal solution in all company pharmacies, which is available at no cost.

Web-Based Pain Management Program Reduces Aberrant Drug Behavior in Chronic Pain

Web-Based Pain Management Program Reduces Aberrant Drug Behavior in Chronic Pain

A web-based self-management program may reduce aberrant drug behaviors and pain catastrophizing in patients with chronic pain treated with opioids.

Opioid Prescriptions for Musculoskeletal Conditions Increase Patient Satisfaction

Opioid Prescriptions for Musculoskeletal Conditions Increase Patient Satisfaction

The researchers found that 13.1% of patients with musculoskeletal conditions were opioid users, and those using prescribed opioids were more likely to be highly satisfied with their care.

Disposal of Unused Opioids After Surgery Improved With Educational Brochure

Disposal of Unused Opioids After Surgery Improved With Educational Brochure

Disseminating an educational brochure improves disposal of unused opioids after surgery.

Potential Opioid Overprescription May Be Common After Most Surgical Procedures

Potential Opioid Overprescription May Be Common After Most Surgical Procedures

Opioids may be overprescribed frequently after surgery in most specialties.

Efficacy of Tamper-Resistant Controlled-Release Oxycodone

Efficacy of Tamper-Resistant Controlled-Release Oxycodone

The tamper-resistant formulation of controlled-release oxycodone in Australia reduced tampering among high-risk populations.

High Bioavailability, Fast Absorption of Buprenorphine With New Sublingual Wafer

High Bioavailability, Fast Absorption of Buprenorphine With New Sublingual Wafer

Preliminary results suggest that a new sublingual buprenorphine wafer may offer high bioavailability and fast absorption for patients treated for acute and chronic pain.

Identification of Active-State Kappa-Opioid Receptor Crystal Structure May Facilitate the Design of Improved Analgesics

Identification of Active-State Kappa-Opioid Receptor Crystal Structure May Facilitate the Design of Improved Analgesics

Elucidation of the crystal structure of κ-opioid receptors in their active state may facilitate the design of optimized analgesics, devoid of psychoactive effects and of addictive properties.

Lower Socioeconomic Indicators Linked to Increase in Opioid Prescriptions

Lower Socioeconomic Indicators Linked to Increase in Opioid Prescriptions

Among disabled Medicare beneficiaries, county-level socioeconomic factors are associated with opioid prescriptions, with more prescriptions seen with lower socioeconomic indicators.