Opioid Addiction

Featured Article

Recommendations for Perioperative Pain Management in Patients With Opioid Tolerance

Recommendations for Perioperative Pain Management in Patients With Opioid Tolerance

With the increasing number of patients presenting to surgery with opioid tolerance, clinicians should be familiar with their specific analgesic needs.

Latest

Methadone Improves Short-Term Outcomes Better Than Morphine in Neonatal Abstinence Syndrome

Methadone Improves Short-Term Outcomes Better Than Morphine in Neonatal Abstinence Syndrome

Methadone may be superior to morphine for reducing hospital length of stay and length of drug treatment in infants with neonatal abstinence syndrome.

Prescribed Opioids Difficulties Scale Effective for Assessing Concerns of Patients With Chronic Pain

Prescribed Opioids Difficulties Scale Effective for Assessing Concerns of Patients With Chronic Pain

The Prescribed Opioids Difficulties Scale may be effective for identifying patients using opioids for chronic noncancer pain who are worried about their usage.

U.S. Surgeon General Urges More Americans to Carry Naloxone

U.S. Surgeon General Urges More Americans to Carry Naloxone

As the rates of opioid overdose deaths are increasing rapidly, the Surgeon General is recommending that more individuals, including family, friends, and those who are personally at risk for an opioid overdose.

Predictors of Opioid Overdose in High-Risk Users

Predictors of Opioid Overdose in High-Risk Users

Having a hepatitis C virus infection, witnessing a friend or others experiencing a drug overdose, and having a history of frequent buprenorphine treatment are factors that may predict the risk for opioid drug overdose in high-risk opioid users.

FDA to Review Long-Acting Treatment for Opioid Use Disorder

FDA to Review Long-Acting Treatment for Opioid Use Disorder

Pending approval, CAM2038 may be the first long-acting treatment for OUD in both weekly and monthly formulations.

Emergency Physicians Offer Recommendations for Identifying and Managing Opioid Use Disorder

Emergency Physicians Offer Recommendations for Identifying and Managing Opioid Use Disorder

American emergency medicine physicians have been taking measures to address the ongoing opioid crisis, which affects emergency departments throughout the country.

Opioid Misuse May Help Predict Alcohol Dependence Treatment Outcomes

Opioid Misuse May Help Predict Alcohol Dependence Treatment Outcomes

Misuse of opioid drugs may affect the outcomes of treatment for alcohol use disorder, and cannabis use may predict the odds of heavy drinking at the end of treatment.

Oxycodone Substitute Shows Lower Abuse Potential

Oxycodone Substitute Shows Lower Abuse Potential

Investigators assessed the potential for abuse associated with NKTR-181, a new mu-opioid receptor agonist analgesic.

FDA Takes Steps to Reconcile Needs of Patients With Chronic Pain, Efforts to Curb Opioid Epidemic

FDA Takes Steps to Reconcile Needs of Patients With Chronic Pain, Efforts to Curb Opioid Epidemic

A panel discussion event held at the US Food and Drug Administration gathered patients with chronic pain and FDA officials, to reconcile concerns around prescriptions of opioid medications with the needs of these patient populations.

Buprenorphine Diversion Driven by Withdrawal Prevention, Abstinence Maintenance

Buprenorphine Diversion Driven by Withdrawal Prevention, Abstinence Maintenance

Researchers deployed a survey to individuals who had received treatment for opioid use disorder to assess their use of buprenorphine.

Lofexidine a Non-Narcotic Option for Opioid Withdrawal Symptoms

Lofexidine a Non-Narcotic Option for Opioid Withdrawal Symptoms

Lofexidine may help patients with opioid withdrawal symptoms or difficulty with opioid discontinuation.

Overdose Risk Highest in First Days of Concurrent Opioid, Benzodiazepine Use

Overdose Risk Highest in First Days of Concurrent Opioid, Benzodiazepine Use

Five-fold increased risk of opioid-related overdose during first 90 days of concurrent use

Physiologically Based Pharmacokinetic Model to Optimize Buprenorphine Treatment During Pregnancy

Physiologically Based Pharmacokinetic Model to Optimize Buprenorphine Treatment During Pregnancy

A physiologically based pharmacokinetic model-based simulation may help optimize buprenorphine therapy during pregnancy.

Oxycodone Substitute Indicates Lower Abuse Potential

Oxycodone Substitute Indicates Lower Abuse Potential

Investigators assessed the potential for abuse associated with NKTR-181, a new mu-opioid receptor agonist analgesic.

Poison Control Center Data Detail Peds Exposure to Buprenorphine

Poison Control Center Data Detail Peds Exposure to Buprenorphine

Children aged 6 have greater odds of hospital admission than teens with single-substance exposure

Prescribing Patterns in Emergency Department May Be Affected by Race, Sex

Prescribing Patterns in Emergency Department May Be Affected by Race, Sex

Patients' race/ethnicity and sex may have an effect on prescribing patterns for opioid and nonopioid medications.

Switching From Buprenorphine-Naltrexone to XR-Naltrexone as Effective as XR-Naltrexone

Switching From Buprenorphine-Naltrexone to XR-Naltrexone as Effective as XR-Naltrexone

Switching to extended-release naltrexone after 3 months receiving buprenorphine-naltrexone may be as effective as XR-NTX from treatment onset in attaining opioid abstinence and treatment completion.

NIH Initiative Aims to Address Opioid Misuse Over Long Term

NIH Initiative Aims to Address Opioid Misuse Over Long Term

A novel, innovative initiative is being developed to help end addiction over the long term, according to a viewpoint article published online June 12 in the Journal of the American Medical Association.

Nature of Opioids Implicated in Deaths Have Shifted for Blacks, Whites Since 1979

Nature of Opioids Implicated in Deaths Have Shifted for Blacks, Whites Since 1979

Causes of opioid-related deaths in the United States have evolved from 1979 to 2015 for both white and black populations.

Opioid, Alcohol Misuse Linked to Lower Functioning in Chronic Pain

Opioid, Alcohol Misuse Linked to Lower Functioning in Chronic Pain

In patients prescribed opioids for chronic pain, those who misuse opioids alone or in combination with alcohol may experience reduced functioning compared with those who do not misuse these substances.