Opioid Addiction

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Betel Quid Addiction and Implications for Substance Use Disorder

Betel Quid Addiction and Implications for Substance Use Disorder

New findings suggest that DSM-5 criteria may apply to betel use disorder and offer opportunities to advance the study and understanding of substance use disorder in general.

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First Opioid Lawsuit Targeting Pharmacy Benefit Managers

First Opioid Lawsuit Targeting Pharmacy Benefit Managers

First lawsuit mentions three largest PBMs; PBMs likely to be increasingly targeted in litigation

Adults Using Benzodiazepines More Likely to Receive Opioid Prescription

Adults Using Benzodiazepines More Likely to Receive Opioid Prescription

New opioid prescriptions for U.S. adults using benzodiazepines stopped increasing in 2010, although the likelihood of receiving a prescription is still elevated versus the general population.

Similar Outcomes for Transplant With Overdose-Death Donors

Similar Outcomes for Transplant With Overdose-Death Donors

Transplantation of organs from overdose-death donors is associated with similar five-year patient survival and graft survival as organs from trauma-death donors and medical-death donors.

Opioid Prescribing Trends in Patients With, Without Cancer

Opioid Prescribing Trends in Patients With, Without Cancer

Individuals with and without cancer may be affected in a similar manner by concerns surrounding opioids that have led to reductions in their prescribing.

How the City of San Francisco Is Tackling the Intertwined HIV/HCV and Opioid Epidemics

How the City of San Francisco Is Tackling the Intertwined HIV/HCV and Opioid Epidemics

Katie Burk, MPH, presented measures undertaken by the city of San Francisco to provide integrated responses to the concurrent HIV/HCV and opioid public health epidemics.

Tackling the Chronic Pain and Opioid Use Disorder Crises Through Public-Private Partnerships

Tackling the Chronic Pain and Opioid Use Disorder Crises Through Public-Private Partnerships

Partnerships between public and private entities could expedite the development of nonaddictive pain therapies and other strategies to address the dual crises of chronic pain and opioid use disorder.

Pain Tolerance in Buprenorphine Maintenance Treatment

Pain Tolerance in Buprenorphine Maintenance Treatment

Buprenorphine maintenance treatment for opioid dependence may result in hyperalgesia and prevent morphine-associated antinociception.

Education, Depression, Pain Associated With Opioid Misuse

Education, Depression, Pain Associated With Opioid Misuse

In adults age 50 or older, higher education, illicit drug use, depression, and pain interference with normal work are significantly associated with opioid misuse.

Pediatric ICU Admissions for Opioid Ingestion Continue to Rise

Pediatric ICU Admissions for Opioid Ingestion Continue to Rise

In this retrospective analysis of the Pediatric Health Information System database, investigators obtained data on pediatric hospitalizations for opioid exposure in the US between 2004 and 2015.

FDA: Social Media Companies Aren't Doing Enough to Stop Illegal Opioid Sales

FDA: Social Media Companies Aren't Doing Enough to Stop Illegal Opioid Sales

A recent report from the U.S. Senate Permanent Subcommittee on Investigations detailed how subcommittee members found it 'easy' to find fentanyl, pay for it and have it shipped to anywhere in the U.S.

Intentional Poisoning as a Method for Obtaining Opioid Medications

Intentional Poisoning as a Method for Obtaining Opioid Medications

According to the authors, this report represents the first case of recurrent fallacious lactatemia secondary to EG poisoning in the setting of drug-seeking behavior.

Treatment Duration of XR Naltrexone for Opioid Dependence and Outcomes

Treatment Duration of XR Naltrexone for Opioid Dependence and Outcomes

A longer duration of extended-release naltrexone treatment in individuals with opioid dependence was associated with improved outcomes and reduced rates of relapse.

Surgeon General Issues Advisory on Importance of Naloxone

Surgeon General Issues Advisory on Importance of Naloxone

In a statement released today, Surgeon General, Jerome M. Adams, MD, MPH, said, "It is time to make sure more people have access to this lifesaving medication, because 77 percent of opioid overdose deaths occur outside of a medical setting and more than half occur at home."

CDC: Overdose Deaths Up Across Drug Categories in 2015 to 2016

CDC: Overdose Deaths Up Across Drug Categories in 2015 to 2016

From 2015 to 2016, there were increases in deaths across all drug categories examined, with 63,632 drug overdose deaths in 2016.

FDA Issues Mandatory Recall of Food Products Containing Powdered Kratom

FDA Issues Mandatory Recall of Food Products Containing Powdered Kratom

The recall is due to samples of the product testing positive for Salmonella.

Pre-Op Chronic Opioid Use Ups Poor Outcomes Post Spinal Fusion

Pre-Op Chronic Opioid Use Ups Poor Outcomes Post Spinal Fusion

Preoperative chronic opioid use is associated with poor outcomes and continued dependence after posterior lumbar fusion.

Helping to End Addiction Long-Term Initiative by NIH Launched to Address Opioid Epidemic

Helping to End Addiction Long-Term Initiative by NIH Launched to Address Opioid Epidemic

National Institutes of Health Director, Francis Collins, MD, PhD, announced on April 4, 2018 the launch of the Helping to End Addiction Long-Term Initiative.

Case Report Reveals Another Possible Side Effect of Kratom

Case Report Reveals Another Possible Side Effect of Kratom

According to the authors, this is the first report of kratom-induced hyperprolactinemia.

Provider Self-Perception of Opioid Prescribing Often Inaccurate, Says Study

Provider Self-Perception of Opioid Prescribing Often Inaccurate, Says Study

Results showed that 65% of those in the intervention group underestimated their opioid prescribing.

Hydrocodone, Oxycodone Linked to Majority of Serious Opioid Adverse Event Cases

Hydrocodone, Oxycodone Linked to Majority of Serious Opioid Adverse Event Cases

The 7 opioids included for analysis were oxycodone, hydrocodone, morphine, hydromorphone, oxymorphone, tapentadol, and tramadol.