OnabotulinumtoxinA at 195 UI may be effective in reducing the number of headaches per month and medication intake in patients with chronic migraine and medication overuse.
This randomized, open-label study examined participant reported outcomes, safety, and tolerability of onabotulinumtoxinA and topiramate in adults with chronic migraines.
Treating chronic migraine with onabotulinumtoxinA may reduce the number of headache days when administered according to the National Institute for Health and Care Excellence guidelines.
A year-long treatment with onabotulinumtoxin A may effectively and safely reduce the number of monthly headaches in individuals with chronic migraine, particularly in individuals with unilateral pain.
The use of onabotulinumtoxinA every 12 weeks over a 2-year period was found to be safe, and effective for headache prevention in patients with chronic migraine.
Despite its prevalence, tension-type headache is often complicated by overlapping symptoms and a weak understanding of tension-type headache etiology.
OnabotulinumtoxinA was shown to have a better outcome in patients with chronic migraine who start the treatment within 12 months of symptom onset.
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