Generic Name and Formulations:
Hydrocodone bitartrate 2.5mg, guaifenesin 200mg; per 5mL; oral soln; raspberry flavor.
ABER Pharmaceuticals, LLC
Indications for OBREDON:
Cough and to loosen mucus associated with the common cold.
Use accurate measuring device. ≥18yrs: 10mL every 4–6hrs. Max 6 doses (60mL) in 24hrs.
<18yrs: not established.
During or within 14 days of MAOIs.
Risks from concomitant use with benzodiazepines or other CNS depressants (see Interactions). Dose-related respiratory depression. Drug dependence. Abuse potential (monitor). Avoid in head injury, other intracranial lesions or pre-existing increase in intracranial pressure. Acute abdomen. Persistent or chronic cough (eg, smoking, asthma, chronic bronchitis, emphysema) or if excessive phlegm: not recommended. Diabetes. Thyroid disorders. Addison's disease. Prostatic hypertrophy. Urethral stricture. Asthma. Severe hepatic or renal impairment. Elderly. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.
Antitussive + expectorant.
See Contraindications. Increased risk of respiratory depression, sedation with benzodiazepines or other CNS depressants (eg, opioids, antihistamines, antipsychotics, anxiolytics, alcohol); avoid. May affect or be affected by MAOIs, TCAs. Paralytic ileus may occur with anticholinergics.
Dizziness, headache, sedation, nausea, diarrhea, decreased blood pressure; respiratory depression.
Clinical Pain Advisor Articles
- Abuse-Deterrent Opioid Formulations: Barriers to Broader Use
- Women Frequently Prescribed High Doses of Opioids After Vaginal Delivery
- Notifications by PDMPs May Not Effectively Reduce Opioid Misuse
- Virtual Reality May Effectively Reduce Sensory, Affective, and Cognitive Pain During Labor
- Medical Cannabis Legalization Associated With Reduced Schedule III Opioid Prescriptions
- Neuropathic Pain Medications
- Higher Buprenorphine Dose May Not Increase Severity of Neonatal Abstinence Syndrome
- Terms Used for Addiction May Be Associated With Explicit, Implicit Bias
- Ketamine Infusions May Be Effective for Refractory Headache
- Physical, Psychosocial Activity May Be Protective Against Development of Chronic Pain in Older Adults
- Opioid Use Disorder Prevalence at Delivery on the Rise in the US, According to CDC
- Suprazygomatic Sphenopalatine Ganglion Block May Quickly Relieve Status Migrainosus Pain
- Pharmacologically Induced Headache Accompanied by Dilated Cephalic Vessels
- IV Lidocaine May Be Safe, Efficacious for Pediatric Status Migraine
- Gray Matter Changes in Migraine Associated With Clinical Characteristics