Potential Genetic Target Identified as Postsurgical Pain Marker

Multigene tests can change hereditary breast, ovarian cancer management.
Multigene tests can change hereditary breast, ovarian cancer management.
Being able to predict which patients are prone to developing chronic pain after surgery could enable clinicians to better prepare pain management strategies.

A study in Anesthesiology suggests a new target for pain control in patients who develop chronic pain after surgery. The target, spinal cathepsin G (CTSG), is a pro-nociceptive mediator in both an animal model and human study. The research points to the potential for inhibiting CTSG through an inhibitor.

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