Specific countries officially recommend some screening questionnaires for the early assessment of neuropathic pain, with France recommending the DN4 and Germany recommending PainDETECT.
A number of factors that include age, the presence of enthesitis, and depressive symptoms may be associated with neuropathic pain in ankylosing spondylitis.
Pain catastrophizing may be associated with reduced psychological — and to a lesser extent physical —function in patients with neuropathic pain and spinal pain.
Neuropathic pain is associated with a more severe multiple sclerosis disease phenotype.
Reviewing the Efficacy, Safety, and Tolerability of Cannabis-Based Medicines for Chronic Neuropathic PainApril 18, 2018
The effectiveness of cannabis-based products for chronic neuropathic pain is not supported by high-quality evidence.
ZTlido is comprised of a non-aqueous adhesive material containing 1.8% lidocaine.
Cotargeting of peripheral μ-opioid and cannabinoid receptors was found to have a synergistic effect in reducing mechanical allodynia in a mouse model of neuropathic pain.
Although peripheral neuropathy is one of the most common neurologic problems seen in the primary care setting, recognizing and evaluating peripheral neuropathy in a patient can be challenging due to its diverse presentations.
A bedside quantitative sensory testing using inexpensive handheld devices indicates that this test may reliably be used to assess sensory profiles in patients with neuropathic pain.
Investigators sought to determine whether repeated intravenous low-dose lidocaine could provide prolonged pain relief in patients with refractory neuropathic pain.
For patients with gluten neuropathy, following a strict gluten-free diet is associated with significantly reduced odds of peripheral neuropathic pain.
Substantial evidence suggests a close connection between neuropathic pain and mood disorders.
Researchers have developed a weighted score that may be useful in the differential diagnosis of complex regional pain syndrome.
Depending on the extent of the injury, pain due to burns can range from mild to severe to excruciating.
Systemic lidocaine administered via IV or patch has consistently shown effectiveness for the treatment and prevention of chronic pain.
Patients with end-stage knee or hip osteoarthritis were found to often experience possible neuropathic pain - particularly pain at rest vs on activity, and in men.
Use of the 2006 vs 2007 criteria for the diagnosis of complex regional pain syndrome may lead to the misdiagnosis of patients experiencing unexplained excessive pain after total knee arthroplasty.
Opioids may be "life-transforming" for patients with refractory restless legs syndrome when taken in relatively low total daily doses, according to new guidelines.
Evidence for the effectiveness of oxcarbazepine in painful diabetic neuropathy and other forms of neuropathic pain is limited.
Treatment with the capsaicin 8% patch Qutenza may be more effective than pregabalin for reducing the intensity and area of dynamic mechanical allodynia and for complete resolution of the disorder.
Chronic pain experienced by patients with pachyonychia congenita may be caused by damage to the peripheral nerve fibers, with the hyperalgesia and allodynia observed in affected regions likely to be manifestations of peripheral sensitization.
Peripheral nerve stimulation may provide long-term pain relief in patients with painful mononeuropathy secondary to leprosy.
After 5 years, 55% of patients had experienced treatment success and 80% of patients with a permanent implant still used their SCS device.
Pain management in athletes requires a clear understanding of the different types of pain and various factors that can contribute to pain in this population.
The use of virtual reality (VR) and multisensory stimulation in patients with spinal cord injury promotes mild relief from chronic neuropathic pain and represents a potentially helpful addition to SCI neurorehabilitation management.
In patients with multiple sclerosis, lesions in the right dorsolateral prefrontal cortex and posterior periventricular area may be associated with hypo and hyperalgesia.
Dronabinol provides a safe and effective treatment option for patients with symptoms of neuropathic pain associated with multiple sclerosis.
As survival rates for patients with burns have improved, the need for effective treatments for chronic pain in this population has become more pressing.
The researchers found that paclitaxel triggers CIPN by altering IP3 receptor phosphorylation and intracellular calcium flux and activating calcium-dependent calpain proteases.
Electrical stimulation and a higher baseline pain score were shown to be associated with a higher chance of improved pain relief with acupuncture.
Clinical Pain Advisor Articles
- Stages of Low Back Pain Have Specific Sets of Clinical Indicators
- FDA Approves Aimovig for Migraine Prevention
- Pain Interference Associated With Depression, Pain Self-Efficacy in Chronic Musculoskeletal Pain
- Factors Associated With Neuropathic Pain in Ankylosing Spondylitis
- Detox vs Medication-Assisted Treatment for Opioid Use Disorder in Pregnancy: Expert Roundtable
- Effect of Prescription Drug Monitoring Programs on Fatal, Nonfatal Drug Overdoses
- Standardized SCS Workflow May Effectively Alleviate Failed Back Surgery Syndrome-Related Pain
- Marijuana Legalization and Opioid Prescribing Rates
- Medical Marijuana Users More Likely to Use Prescription Drugs for Medical, Nonmedical Purposes
- Interbrain Coupling During Handholding Associated With Analgesia, Empathy
- Recommendations Developed for Managing Postpartum Pain
- Cryoablation Efficacious for Cancer Pain, Review Finds
- Art Intervention Clinically Effective in Treating Cancer-Related Pain, Mood Symptoms
- Pain, Cognitive Dysfunction in SLE Mediated by Sleep Disturbance, Depression
- PTSD Symptoms and the Acute Pain Response in Low-Income Women