Naltrexone

Naltrexone May Mitigate Stimulant-Induced Euphoria Associated With ADHD Treatment

Naltrexone May Mitigate Stimulant-Induced Euphoria Associated With ADHD Treatment

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Euphoria associated with the stimulant methylphenidate may be mitigated by co-administration of naltrexone in patients with attention-deficit/hyperactivity disorder.

Treatment Duration of XR Naltrexone for Opioid Dependence and Outcomes

Treatment Duration of XR Naltrexone for Opioid Dependence and Outcomes

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A longer duration of extended-release naltrexone treatment in individuals with opioid dependence was associated with improved outcomes and reduced rates of relapse.

Opioid Dependence Pharmacotherapy and Clinical, Criminal Outcomes in Mental Illness

Opioid Dependence Pharmacotherapy and Clinical, Criminal Outcomes in Mental Illness

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All 3 opioid-dependence pharmacotherapies — methadone, buprenorphine, and oral naltrexone — were associated with reductions in inpatient substance abuse treatment.

Extended-Release Naltrexone Injections Reduce Opioid Dependence

Extended-Release Naltrexone Injections Reduce Opioid Dependence

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Compared with buprenorphine-naloxone, use of extended-release naltrexone maintained abstinence from heroin and other illicit substances at a similar rate.

Buprenorphine and Naltrexone Underprescribed for Youth With Opioid Use Disorder

Buprenorphine and Naltrexone Underprescribed for Youth With Opioid Use Disorder

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Early pharmacologic intervention for opioid use disorder after diagnosis is crucial to prevent relapse and overdose in adolescents and young adults.

Naloxone: Policies and Access

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Policies have helped make naloxone more available, thus contributing to the reduction of opioid-related deaths in the U.S.

Naltrexone vs Buprenorphine to Treat Opioid Dependence

Naltrexone vs Buprenorphine to Treat Opioid Dependence

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An 8-day detoxification process using low-dose oral naltrexone showed superior efficacy to the standard 15-day approach that uses an agonist taper leading to induction with extended-release naltrexone

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