Migraine

White Matter Hyperintensities Linked to Tension-Type Headaches

White Matter Hyperintensities Linked to Tension-Type Headaches

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Investigators sought to determine the relationship between headache and white matter hyperintensities.

Transcranial Magnetic Stimulation May Prevent Migraine in Adolescents

Transcranial Magnetic Stimulation May Prevent Migraine in Adolescents

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Researchers conducted an open-label prospective study to assess the use of single-pulse transcranial magnetic stimulation for the management of migraine headache in adolescents.

Tobacco Exposure Influences Cluster Headache Presentation

Tobacco Exposure Influences Cluster Headache Presentation

The United States Cluster Headache Survey assessed tobacco exposure in individuals with cluster headaches.

Dextromethorphan/Quinidine May Relieve Migraine in MS Patients With PBA

Dextromethorphan/Quinidine May Relieve Migraine in MS Patients With PBA

Researchers conducted an open-label observational study to assess the safety and efficacy of dextromethorphan/quinidine as migraine prophylaxis for individuals with pseudobulbar affect.

Novel Nasal Spray for Migraine Attacks to Be FDA-Reviewed

Novel Nasal Spray for Migraine Attacks to Be FDA-Reviewed

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DFN-02 was evaluated in a multicenter, double-blind, randomized, placebo-controlled study (N=107) which showed it was effective in treating pain and associated symptoms during a migraine attack and in reducing attack-related functional disability.

Parenteral Hydromorphone for Migraine and ED Revisits

Parenteral Hydromorphone for Migraine and ED Revisits

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Hydromorphone-related "likeability" and "feeling good" may not be associated with return visits to the emergency department in patients treated with the drug for migraine.

Incidence of Musculoskeletal Disorders, Depression in Migraine

Incidence of Musculoskeletal Disorders, Depression in Migraine

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Fibromyalgia, osteoarthritis, sciatic syndrome, rheumatoid arthritis, and moderate depression may be more prevalent in working-age individuals with vs without migraine.

Overlapping Headache and Sleep Disorders: Which Comes First and How to Treat?

Overlapping Headache and Sleep Disorders: Which Comes First and How to Treat?

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Clinicians discuss the clinical implications of headache and comorbid sleep disturbances.

Single Pulse Transcranial Magnetic Stimulation Shows Efficacy in Migraine Prevention

Single Pulse Transcranial Magnetic Stimulation Shows Efficacy in Migraine Prevention

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Investigators sought to evaluate the efficacy and tolerability of sTMS for migraine prevention.

Prevalence and Predictors of Pain in COPD

Prevalence and Predictors of Pain in COPD

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Patients with chronic obstructive pulmonary disease (COPD) may be more likely to experience chronic neck pain, lower back pain and migraine than individuals without COPD.

Efficacy of Greater Occipital Nerve Block for the Acute Treatment of Migraine Headache

Efficacy of Greater Occipital Nerve Block for the Acute Treatment of Migraine Headache

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Greater occipital nerve block may be an effective option for the acute management of migraine headache.

Surgical Outcomes Associated With Trigger Site Deactivation for Migraines

Surgical Outcomes Associated With Trigger Site Deactivation for Migraines

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In some patients, surgical trigger site deactivation may treat migraine effectively and relieve symptoms substantially.

Pseudotumor Cerebri Syndrome vs Migraine in Children: Differential Diagnosis

Pseudotumor Cerebri Syndrome vs Migraine in Children: Differential Diagnosis

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The illustration of headache symptoms through drawings may help clinicians distinguish between pseudotumor cerebri syndrome and migraine in pediatric patients.

Diagnosing Migrainous Aura With Perfusion CT

Diagnosing Migrainous Aura With Perfusion CT

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Perfusion computed tomography offers greater accuracy in diagnosing migrainous aura and differentiating symptoms from those present in stroke in patients presenting with acute onset of neurological symptoms.

Effect of Parental Migraine on Adolescents

Effect of Parental Migraine on Adolescents

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The researchers conducted a longitudinal Web-based study called the Chronic Migraine Epidemiology and Outcomes study with cross-sectional modules that assessed an array of migraine-related outcomes

Sumatriptan Needle-Free Injection for Migraine Discontinued

Sumatriptan Needle-Free Injection for Migraine Discontinued

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Sumavel DosePro was approved in 2009 for the acute treatment of migraine or cluster headaches as a needle-free delivery system supplied in prefilled pens, and is being discontinued.

Assessing the Value of Brain MRI in Migraine With Normal Neurologic Exam

Assessing the Value of Brain MRI in Migraine With Normal Neurologic Exam

Routine brain magnetic resonance imaging is not necessary for those with migraine who have normal neurologic function unless there is a clear clinical indication that there are underlying structural abnormalities.

Growing Number of Genetic, Neuroimaging Markers for Migraine With Advances in Research

Growing Number of Genetic, Neuroimaging Markers for Migraine With Advances in Research

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Advancements in research have led to the identification of a growing number of genetic and neuroimaging markers of migraine.

Cerebellar Hypoperfusion, Crossed Cerebellar Diaschisis in Migraine With Aura

Cerebellar Hypoperfusion, Crossed Cerebellar Diaschisis in Migraine With Aura

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Researchers analyzed patients with migraine who underwent magnetic resonance imaging and dynamic susceptibility contrast perfusion.

Targeted Group Education for Chronic Headache in Adolescents

Targeted Group Education for Chronic Headache in Adolescents

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Researchers reviewed survey results to determine whether adolescents with chronic headache might benefit from either a 1-time comprehensive evaluation and management plan or standard care.

Diabetes, Insulin Therapies, and Migraine Risk

Diabetes, Insulin Therapies, and Migraine Risk

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The presence of diabetes — both types 1 and 2 — may be associated with a reduced risk for migraine

Migraine Linked to Presence of aPS/PT Antibodies in Primary Antiphospholipid Syndrome

Migraine Linked to Presence of aPS/PT Antibodies in Primary Antiphospholipid Syndrome

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The presence of antibodies to phosphatidylserine/prothrombin complex is associated with Raynaud phenomenon and migraine in patients with primary antiphospholipid syndrome.

Acupuncture, Physiotherapy Combination May Benefit Patients With Tension-Type Headache

Acupuncture, Physiotherapy Combination May Benefit Patients With Tension-Type Headache

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Patients with tension-type headache experience benefit from acupuncture and stretching, especially in combination with pressure pain threshold physiotherapy hands-on techniques.

Migraine Burden May Be Reduced With Physical Activity

Migraine Burden May Be Reduced With Physical Activity

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Recent research has found that exercise reduced the burden of migraine and the ability to engage in physical activity by reducing the effect of tension-type headache and neck pain.

Migraines and Risk for Cardiovascular Comorbidities

Migraines and Risk for Cardiovascular Comorbidities

Migraines are associated with elevated risks in several cardiovascular comorbidities, including myocardial infarction, stroke, and venous thromboembolism.

Probable Medication Overuse in Elderly With Migraine

Probable Medication Overuse in Elderly With Migraine

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The prevalence of probable medication overuse may be high in elderly patients with migraine, and higher frequency of migraine may be associated with early onset in this patient population.

Erenumab Shows Promise in Treatment-Resistant Migraine

Erenumab Shows Promise in Treatment-Resistant Migraine

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A recent study evaluated the safety and efficacy of erenumab in patients with episodic migraine who had experienced 2 to 4 previous preventive treatment failures, due to lack of efficacy or intolerable side effects.

Evaluating Day-to-Day Variations in Migraine, Non-Migraine Headaches

Evaluating Day-to-Day Variations in Migraine, Non-Migraine Headaches

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The frequency, intensity, and daily interference of headaches change over a 6-month period, with day-to-day variation being more volatile in migraine than in non-migraine headaches.

CGRP Antagonist Shows Effectiveness in Acute Migraine

CGRP Antagonist Shows Effectiveness in Acute Migraine

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Allergan has announced positive Phase 3 trial results for ubrogepant, a novel calcitonin gene-related peptide receptor antagonist for the acute treatment of migraine.

Episodic Migraine-Related White Matter Hyperintensities Ipsilateral to Pain

Episodic Migraine-Related White Matter Hyperintensities Ipsilateral to Pain

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Pain experienced by patients during episodic migraine is associated with the occurrence of white matter hyperintensities in the cerebral hemisphere ipsilateral to the pain side.

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