Migraine

Topical Migraine Trigger Point Treatment as Effective as Injection

Topical Migraine Trigger Point Treatment as Effective as Injection

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In a retrospective analysis, investigators assessed the effects of topical trigger point treatments on headache symptoms in patients with migraine.

Kinesiophobia May Be Associated With Greater Cutaneous Allodynia in Migraine

Kinesiophobia May Be Associated With Greater Cutaneous Allodynia in Migraine

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Approximately half of patients with migraine have kinesiophobia, and the condition is associated with greater severity, not presence of cutaneous allodynia.

A Potential Biomarker for Predicting Antibody Treatment Efficacy in Migraine

A Potential Biomarker for Predicting Antibody Treatment Efficacy in Migraine

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Researchers showed high migraine induction capabilities with calcitonin gene-related peptide (CGRP) in people with migraine who responded to erenumab treatment compared to data from previous CGRP provocation experiments.

Serum Vitamin D Levels and Risk for Migraine

Serum Vitamin D Levels and Risk for Migraine

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Higher levels of serum 25-hydroxyvitamin D may be associated with lower risk for migraine headaches.

Migraine Associated With Self-Reported ADHD Symptoms in University Students

Migraine Associated With Self-Reported ADHD Symptoms in University Students

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Migraine may be associated with self-reported attention deficit and hyperactivity disorder symptoms in university students.

Erenumab as a Therapy for Hard to Treat Episodic Migraine

Erenumab as a Therapy for Hard to Treat Episodic Migraine

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Erenumab 140 mg is a well-tolerated and potentially effective preventive treatment for patients with episodic migraine, according to a phase 3b study.

Migraine Treatment in the ED: Overcoming Our Penchant for Opioids

Migraine Treatment in the ED: Overcoming Our Penchant for Opioids

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There is significant evidence that opioids are not the right treatment of choice for migraine in the emergency department.

Genetic Risk Score Predicts Response to Triptans for Migraines Without Aura

Genetic Risk Score Predicts Response to Triptans for Migraines Without Aura

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Genetic risk scores that focus on 2 single-nucleotide polymorphisms associated with migraines without aura might help predict patient response to triptan treatment.

Higher Headache Medication Use Not Associated With Higher Achievement Motivation

Higher Headache Medication Use Not Associated With Higher Achievement Motivation

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Study showed no evidence for an effect of achievement motivation on the frequency of acute headache medication use.

Nonexpert Clinicians Lack Tools for Diagnosing Headache Disorders

Nonexpert Clinicians Lack Tools for Diagnosing Headache Disorders

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There is a need for a tool in primary care to aid in managing and diagnosing headache disorders.

Assessing Headache Management Practices at Community Pharmacies

Assessing Headache Management Practices at Community Pharmacies

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Counseling practices and headache management indicate the need for training and education of pharmacists in an Ethiopian city to better serve individuals with headache complaints.

Pain Acceptance May Reduce Headache-Related Disability in Migraine

Pain Acceptance May Reduce Headache-Related Disability in Migraine

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Improved pain acceptance may be associated with a decrease in headache-related disability in patients with migraine.

IV Fluid Use Up, Narcotics Use Down in Patients With Migraine Admitted to ED

IV Fluid Use Up, Narcotics Use Down in Patients With Migraine Admitted to ED

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A study looked at use of IV fluids, ketorolac, dexamethasone, and DRAs prochlorperazine/metoclopramide from 1999-2000 to 2014 in the treatment of patients with migraine admitted to the ED.

Lasmiditan NDA Submitted for Acute Treatment of Migraine

Lasmiditan NDA Submitted for Acute Treatment of Migraine

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The NDA submission included data from two Phase 3 trials, SAMURAI and SPARTAN.

Nonsinogenic Headache vs Chronic Rhinosinusitis Differential Diagnosis Based on SNOT-22 Patterns

Nonsinogenic Headache vs Chronic Rhinosinusitis Differential Diagnosis Based on SNOT-22 Patterns

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Distinct response patterns of the 22-item Sino-Nasal Outcome Test may be used to distinguish nonsinogenic headaches from chronic rhinosinusitis.

The Comorbidity of Migraine and ADHD: Is There a Link?

The Comorbidity of Migraine and ADHD: Is There a Link?

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Investigators examined the link between migraine and attention-deficit/hyperactivity disorder.

Opioid Prescription Rates for Pediatric Headaches Vary by Provider Specialty

Opioid Prescription Rates for Pediatric Headaches Vary by Provider Specialty

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Investigators examined opioid prescribing trends in children and adolescents with primary headaches during ambulatory and emergency department visits.

Persistent Poststroke Headache: Finding Its Place in Stroke Aftercare

Persistent Poststroke Headache: Finding Its Place in Stroke Aftercare

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The continued observation of this delayed headache syndrome may point to a different pathophysiology from tension-type headache or acute poststroke headache.

Documentation Initiative Improves Headache Treatment and Research

Documentation Initiative Improves Headache Treatment and Research

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The authors built a customized structured clinical documentation support toolkit that collects hundreds of fields of discrete, standardized data.

Migraine Subgroups Indentified Based on Comorbidity Profiles

Migraine Subgroups Indentified Based on Comorbidity Profiles

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Investigators identify subgroups of individuals with migraine based on comorbidities and concomitant condition.

Pulse Focused Ultrasound: A Potential Therapeutic Option for Migraines

Pulse Focused Ultrasound: A Potential Therapeutic Option for Migraines

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Investigators aim to develop a non-invasive treatment for medically refractory chronic migraine not requiring a permanent implant.

Privacy Issues in Headache and Migraine Smartphone Applications

Privacy Issues in Headache and Migraine Smartphone Applications

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Many headache smartphone applications or "apps" share information with third parties, more than half of which have privacy policies stating that the shared data will be used to serve targeted advertisements from third parties.

Freedom From Most Bothersome Headache-Associated Symptom Feasible as Primary End Point

Freedom From Most Bothersome Headache-Associated Symptom Feasible as Primary End Point

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Investigators examine most bothersome headache-associated symptoms as a feasible alternative to using 4 c-primary end points in acute migraine treatment trials.

Co-Prescription of Opioids and Antidepressants Prevalent in Migraine

Co-Prescription of Opioids and Antidepressants Prevalent in Migraine

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Researchers sought to assess the prevalence of concomitant prescribing of opioid analgesics with a triptan or a serotogeneric antidepressant in individuals with migraine.

New Device Available for Patients With Episodic Cluster Headache, Migraine

New Device Available for Patients With Episodic Cluster Headache, Migraine

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The Sapphire has a rechargeable and reloadable fill capacity; it can be activated monthly by inputting a unique, prescription-only authorization code, delivered via a radio-frequency identification card that is mailed to the patient.

Overuse of Neuroimaging in the Emergency Department Reported for Pediatric Headache

Overuse of Neuroimaging in the Emergency Department Reported for Pediatric Headache

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Investigators examined rates, predictors, and outcomes of neuroimaging in pediatric and adolescent patients who presented to the ED with a headache.

Migraine Associated With Increased Risk for Postsurgical 30-Day Hospital Readmission for Pain

Migraine Associated With Increased Risk for Postsurgical 30-Day Hospital Readmission for Pain

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Patients with migraine headaches—particularly those accompanied by aura—may be at significantly increased risk for 30-day hospital readmission because of pain after surgery.

Erenumab May Help Prevent Migraines in Patients With Heart Disease

Erenumab May Help Prevent Migraines in Patients With Heart Disease

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Investigators assessed the effect of erenumab on total exercise time, time to exercise-induced angina, and ST depression in patients with stable angina.

No Significant Clinical Differences Between Cluster Headaches With and Without Aura

No Significant Clinical Differences Between Cluster Headaches With and Without Aura

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No significant clinical differences have been found between individuals with cluster headache who experience aura vs no aura.

Managing Comorbid Migraine and Mood Disorders: A Synergistic Approach

Managing Comorbid Migraine and Mood Disorders: A Synergistic Approach

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People with migraines and comorbid mood disorders often need treatments that address both conditions, as well as management of sleep, stress, and lifestyle issues.

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