Migraine

Co-Prescription of Opioids and Antidepressants Prevalent in Migraine

Co-Prescription of Opioids and Antidepressants Prevalent in Migraine

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Researchers sought to assess the prevalence of concomitant prescribing of opioid analgesics with a triptan or a serotogeneric antidepressant in individuals with migraine.

Overuse of Neuroimaging in the Emergency Department Reported for Pediatric Headache

Overuse of Neuroimaging in the Emergency Department Reported for Pediatric Headache

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Investigators examined rates, predictors, and outcomes of neuroimaging in pediatric and adolescent patients who presented to the ED with a headache.

Migraine Associated With Increased Risk for Postsurgical 30-Day Hospital Readmission for Pain

Migraine Associated With Increased Risk for Postsurgical 30-Day Hospital Readmission for Pain

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Patients with migraine headaches—particularly those accompanied by aura—may be at significantly increased risk for 30-day hospital readmission because of pain after surgery.

Erenumab May Help Prevent Migraines in Patients With Heart Disease

Erenumab May Help Prevent Migraines in Patients With Heart Disease

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Investigators assessed the effect of erenumab on total exercise time, time to exercise-induced angina, and ST depression in patients with stable angina.

No Significant Clinical Differences Between Cluster Headaches With and Without Aura

No Significant Clinical Differences Between Cluster Headaches With and Without Aura

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No significant clinical differences have been found between individuals with cluster headache who experience aura vs no aura.

Managing Comorbid Migraine and Mood Disorders: A Synergistic Approach

Managing Comorbid Migraine and Mood Disorders: A Synergistic Approach

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People with migraines and comorbid mood disorders often need treatments that address both conditions, as well as management of sleep, stress, and lifestyle issues.

Hemiplegic Migraine Aura Alleviated by OnabotulinumtoxinA Injections

Hemiplegic Migraine Aura Alleviated by OnabotulinumtoxinA Injections

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Investigators examined the effect of onabotulinumtoxinA on aura frequency and severity in patients with hemiplegic migraine.

Migraine Pain Location May Not Have Clinical Implications

Migraine Pain Location May Not Have Clinical Implications

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The location of migraine pain may not be associated with psychiatric distress, emergency department visits, or healthcare use.

Oral Steroids Perform Better Than Injection in Short-Term Cluster Headache Management

Oral Steroids Perform Better Than Injection in Short-Term Cluster Headache Management

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Investigators examined the efficacy of oral steroids and greater occipital nerve injections as transitional therapies for cluster headache management.

Cognitive Performance, Mood Deficits, White Matter Hyperintensities in Migraine

Cognitive Performance, Mood Deficits, White Matter Hyperintensities in Migraine

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Carefully assessing cognitive performance using a screening test to detect visuospatial/executive, attention, and memory dysfunction in patients with migraine.

Adverse Childhood Events Associated With Medication Overuse Headache

Adverse Childhood Events Associated With Medication Overuse Headache

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Known risk factors for medication overuse headache include smoking, anxiety, family history of substance abuse, migraine history, depression, and obsessive-compulsive disorder.

Two-Thirds of Parents Report Their Child Has Had Headache

Two-Thirds of Parents Report Their Child Has Had Headache

Two-thirds of parents report that their child has had a headache not related to a fall or head injury.

Cardiovascular, Psychiatric Comorbidity Patterns Evident in Migraine

Cardiovascular, Psychiatric Comorbidity Patterns Evident in Migraine

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The comorbidities commonly reported in patients with migraine include those involving cardiovascular, psychiatric, pain, and respiratory conditions, the researchers reported.

Fremanezumab Effective in Reversion of Chronic Migraine to Episodic Migraine

Fremanezumab Effective in Reversion of Chronic Migraine to Episodic Migraine

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This Phase III, multicenter, double-blind study sought to explore the effect of fremanezumab on the potential reversion from chronic migraine to episodic migraine.

Men With Migraines May Have Increased Serum Estradiol, Androgen Deficiency

Men With Migraines May Have Increased Serum Estradiol, Androgen Deficiency

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Men with migraines were found to have increased levels of estradiol and to be more likely to have relative androgen deficiency compared with men without migraines.

Erenumab Reduces Monthly Migraine Days in Patients With Treatment-Resistant Migraine

Erenumab Reduces Monthly Migraine Days in Patients With Treatment-Resistant Migraine

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Patients with difficult-to-treat migraine were randomly assigned 1:1 to either 140 mg erenumab or placebo.

Addressing Rare Headache Disorders: Acute Confusional Migraine

Addressing Rare Headache Disorders: Acute Confusional Migraine

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Acute confusional migraine has not been specifically studied and many clinicians remain unaware of the condition, which may result in underestimation of the prevalence.

Half of Patients Referred for Behavioral Treatment of Migraine Never Initiate Treatment

Half of Patients Referred for Behavioral Treatment of Migraine Never Initiate Treatment

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Approximately half of patients who were referred for behavioral treatment for migraine were found to initiate treatment.

Low-Dose Sumatriptan Injection Effective as Acute Migraine Treatment

Low-Dose Sumatriptan Injection Effective as Acute Migraine Treatment

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A phase 3 study examined a low-dose subcutaneous autoinjection of sumatriptan in the acute treatment of migraines with or without aura in adults.

Poll: Should Migraineurs Avoid Headache Triggers?

Poll: Should Migraineurs Avoid Headache Triggers?

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Dr Richard Lipton and Dr Paul Martin debated the pros and cons of trigger avoidance in patients with migraine headache at the 2018 American Headache Society Annual Scientific Meeting in San Francisco, California.

History of Migraine May Be Associated With Higher Risk for Cochlear Disorders

History of Migraine May Be Associated With Higher Risk for Cochlear Disorders

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The risk for cochlear disorders — particularly tinnitus — may be higher in individuals with a history of migraine.

Hormonal Contraceptives and Migraine: Is It Time to Revisit Stroke Risk?

Hormonal Contraceptives and Migraine: Is It Time to Revisit Stroke Risk?

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Current oral contraceptive products contain lower doses of estrogen than those used in the past, prompting reconsideration of risks and benefits.

Novel Oral Treatment Safe, Effective for Migraine Headache Relief

Novel Oral Treatment Safe, Effective for Migraine Headache Relief

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The 2 randomized, phase 3, double-blind studies included in this presentation were the SAMURAI and SPARTAN trials.

Chronic Migraine Associated With Age-Related Changes in Cortical Thickness

Chronic Migraine Associated With Age-Related Changes in Cortical Thickness

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Individuals with chronic migraine may present with age-related changes in cortical thickness.

Color-Selective Photophobia More Prevalent During Ictal vs Interictal Phase

Color-Selective Photophobia More Prevalent During Ictal vs Interictal Phase

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Color-selective photophobia was found to be more prevalent during the ictal vs interictal phase in individuals with migraine.

Greater Occipital Nerve Block Effective for Acute Relief of Refractory Migraine

Greater Occipital Nerve Block Effective for Acute Relief of Refractory Migraine

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The treatment may be beneficial in patients whose acute migraine does not respond to standard treatment with intravenous metoclopramide.

Eptinezumab May Provide Fast, Effective Reduction of Monthly Migraine Days

Eptinezumab May Provide Fast, Effective Reduction of Monthly Migraine Days

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Eptinezumab has shown 100% bioavailability when administered intravenously.

Headache Calendar Helps Patients Track Relationship Between Headache, Triggers

Headache Calendar Helps Patients Track Relationship Between Headache, Triggers

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This cross-sectional, observational study sought to evaluate the accuracy of individuals with headache to appraise the relationship between potential trigger factors and headache events.

Intravenous Eptinezumab Effectively Reduces Monthly Migraine Days

Intravenous Eptinezumab Effectively Reduces Monthly Migraine Days

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More patients in the 100 mg and 300 mg eptinezumab groups achieved a 100% reduction in monthly migraine days over the 112 weeks compared with placebo.

Menopause Transition Often Prompts Changes in Migraine Pattern, Characteristics

Menopause Transition Often Prompts Changes in Migraine Pattern, Characteristics

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This retrospective study sought to assess migraine patterns in 69 menopausal women between ages 40 and 60 who were treated at Partners Healthcare Hospitals for concurrent migraine headache.

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