Migraine and Headache

Hemicrania Continua: Diagnosis and Treatment

Hemicrania Continua: Diagnosis and Treatment

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Hemicrania continua, one of the trigeminal primary headaches, causes intense unilateral pain for ≥3 months.

Galcanezumab Safe, Effective for Reducing Monthly Migraine Days

Galcanezumab Safe, Effective for Reducing Monthly Migraine Days

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Long-term treatment with galcanezumab was found to be safe and effective for reducing the number of monthly migraine headache days in individuals with chronic or episodic migraine.

Neuroimaging in Headache Disorders: When Is It Necessary?

Neuroimaging in Headache Disorders: When Is It Necessary?

The use of neuroimaging as a diagnostic tool remains at the discretion of the clinician, necessitating more research to improve clinical understanding of primary and secondary headaches.

Chronic Migraine Associated With Increased Risk for Poor Sleep Quality

Chronic Migraine Associated With Increased Risk for Poor Sleep Quality

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Patients with chronic vs episodic migraine may be at increased risk for sleep apnea and poor sleep quality.

Update on Anti-CGRP Therapies Presented at AHS 2018 Meeting

Update on Anti-CGRP Therapies Presented at AHS 2018 Meeting

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A literature review on anti-calcitonin gene-related peptide therapies for the treatment of headache sought to provide an update reflecting new information that was presented at the American Headache Society 60th Scientific meeting.

Hybrid Cognitive Behavioral Therapy Acceptable in Patients With Pediatric Migraine, Insomnia

Hybrid Cognitive Behavioral Therapy Acceptable in Patients With Pediatric Migraine, Insomnia

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Investigators sought to determine whether hybrid cognitive behavioral therapy is effective for youths with chronic migraine and insomnia.

Rimegepant Orally Dissolving Formulation Provides Rapid Relief From Acute Migraine

Rimegepant Orally Dissolving Formulation Provides Rapid Relief From Acute Migraine

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Zydis® (rimegepat orally dissolving tablet) may provide fast relief from migraine-associated pain.

Treating Acute Migraine During Pregnancy: The Need for Guidelines

Treating Acute Migraine During Pregnancy: The Need for Guidelines

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Pregnant women presenting with migraine to acute care settings were found to be treated with therapeutic agents ranging from safe and effective medications to others with unclear efficacy and potential teratogenicity.

Barriers to Nonpharmacologic Treatment Adherence for Headache

Barriers to Nonpharmacologic Treatment Adherence for Headache

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Psychological factors such as attitudes, beliefs, and motivation level may affect adherence with nonpharmacologic therapies for headaches.

FDA Clears nVNS Therapy for Prevention of Cluster Headache

FDA Clears nVNS Therapy for Prevention of Cluster Headache

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The FDA clearance was based on data from 2 studies.

High Daily Stress Linked to Migraine Prevalence in Women

High Daily Stress Linked to Migraine Prevalence in Women

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The investigators sought to evaluate the prevalence of migraines, as well as the effect of sex and stress on migraines.

Microvascular Decompression Favored for the Treatment of Cranial Nerve Neuralgias

Microvascular Decompression Favored for the Treatment of Cranial Nerve Neuralgias

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Cranial nerve neuralgias have increasingly been treated with microvascular decompression surgery to the detriment of percutaneous rhizotomies since 2000.

High Frequency of Headaches Following Dialysis Associated With BUN and Blood Pressure

High Frequency of Headaches Following Dialysis Associated With BUN and Blood Pressure

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Compared with patients not reporting headache, patients with HRH had significantly greater differences in pre- and post-BUN values.

Galcanezumab Effective at Decreasing Monthly Headache Days in Migraine

Galcanezumab Effective at Decreasing Monthly Headache Days in Migraine

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Approximately 40% of patients with episodic migraine who were treated with galcanezumab achieved 100% response rate for at least 1 month.

Jolt Accentuation of Headache Not a Universal Indicator of Acute Meningitis

Jolt Accentuation of Headache Not a Universal Indicator of Acute Meningitis

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The analysis revealed that oversimplifications led to the misconception of jolt accentuation of headache as a stand-alone, universal indicator of acute meningitis.

Examining the Efficacy of Different Oxygen Flow Rates for Cluster Headache Attacks

Examining the Efficacy of Different Oxygen Flow Rates for Cluster Headache Attacks

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The safety and efficacy of oxygen treatment for cluster headache attacks with oxygen delivered at a flow rate of 7 L/min and 12 L/min may be comparable.

Early Onset of Efficacy After Erenumab Treatment in Chronic and Episodic Migraines

Early Onset of Efficacy After Erenumab Treatment in Chronic and Episodic Migraines

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The onset of erenumab efficacy is observable within the first week post-treatment in patients with chronic and episodic migraines.

Effect of Trigeminal Pathway Symptoms on Quality of Life in Chronic Episodic Migraine

Effect of Trigeminal Pathway Symptoms on Quality of Life in Chronic Episodic Migraine

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Abnormal sleep latency and impaired function related to concentration issues may occur more frequently in patients with chronic vs episodic migraine.

Guidelines on the Use of OnabotulinumtoxinA for Chronic Migraine

Guidelines on the Use of OnabotulinumtoxinA for Chronic Migraine

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Researchers and pain experts formulated guidelines for the use of onabotulinumtoxinA for the management of chronic migraine.

Review of Factors Impacting Sport-Related Concussion Headaches

Review of Factors Impacting Sport-Related Concussion Headaches

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Investigators evaluate pre- and post-injury factors associated with post-concussion headache.

OnabotulinumtoxinA Injections Reduce Frequency of Cluster Headaches

OnabotulinumtoxinA Injections Reduce Frequency of Cluster Headaches

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Injections of onabotulinumtoxinA at the sphenopalatine ganglion provide long-term relief for patients with chronic cluster headaches.

Guideline for Diagnosis and Treatment of Idiopathic Intracranial Hypertension

Guideline for Diagnosis and Treatment of Idiopathic Intracranial Hypertension

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The European Headache Federation has issued recommendations on how to best diagnose and treat idiopathic intracranial hypertension.

High-Flow Oxygen Therapy as Effective as Sumatriptan for Cluster Headaches

High-Flow Oxygen Therapy as Effective as Sumatriptan for Cluster Headaches

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The effectiveness, tolerability, and use of inhaled oxygen compared with injectable sumatriptan was examined by utilizing a patient reported survey.

Increased Risk for Suicide Attempts in Patients With Status Migrainosus

Increased Risk for Suicide Attempts in Patients With Status Migrainosus

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Investigators examine risk factors associated with suicide attempt in patients with status migrainosus

Headache Specialists Dissatisfied With Emergency Department Headache Care

Headache Specialists Dissatisfied With Emergency Department Headache Care

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Investigators used a survey to better understand whether headache specialists adhere to headache management protocols and the strategies used to prevent ED visits for headache.

Pediatric Migraine: Evidence-Based Alternative Management

Pediatric Migraine: Evidence-Based Alternative Management

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Recent high-quality clinical trial evidence has demonstrated that medications commonly prescribed for migraine prevention in pediatric patients were not superior to placebo for reducing headache symptoms.

Expert Opinion: CGRP Receptor Antagonist Use in Pediatric Patients With Migraine

Expert Opinion: CGRP Receptor Antagonist Use in Pediatric Patients With Migraine

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Recommendations on the use of these agents in this patient population were published in a Views and Perspectives paper in the journal Headache.

Erenumab Superior to Placebo for Reducing Migraine Disability, Improving HRQoL

Erenumab Superior to Placebo for Reducing Migraine Disability, Improving HRQoL

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A significantly lower percentage of patients receiving a 70-mg or 140-mg dose of erenumab had severe disability during treatment compared with placebo.

Insomnia May Increase Risk for Migraine and Non-Migraine Headache

Insomnia May Increase Risk for Migraine and Non-Migraine Headache

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Individuals who experience insomnia may be more likely to have migraine and non-migraine headache compared with those without insomnia.

Effects of Mindfulness Therapy, Pharmacologic Prophylaxis on Catecholamine Levels in Migraine

Effects of Mindfulness Therapy, Pharmacologic Prophylaxis on Catecholamine Levels in Migraine

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Mindfulness-based practices and treatment programs may be associated with similar changes in plasma levels of catecholamines compared with pharmacologic prophylaxis in patients with migraine and medication overuse headache.

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