Migraine & Headache

Galcanezumab Effective at Decreasing Monthly Headache Days in Migraine

Galcanezumab Effective at Decreasing Monthly Headache Days in Migraine

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Approximately 40% of patients with episodic migraine who were treated with galcanezumab achieved 100% response rate for at least 1 month.

The Comorbidity of Migraine and ADHD: Is There a Link?

The Comorbidity of Migraine and ADHD: Is There a Link?

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Investigators examined the link between migraine and attention-deficit/hyperactivity disorder.

Opioid Prescription Rates for Pediatric Headaches Vary by Provider Specialty

Opioid Prescription Rates for Pediatric Headaches Vary by Provider Specialty

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Investigators examined opioid prescribing trends in children and adolescents with primary headaches during ambulatory and emergency department visits.

Examining the Efficacy of Different Oxygen Flow Rates for Cluster Headache Attacks

Examining the Efficacy of Different Oxygen Flow Rates for Cluster Headache Attacks

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The safety and efficacy of oxygen treatment for cluster headache attacks with oxygen delivered at a flow rate of 7 L/min and 12 L/min may be comparable.

Effect of Trigeminal Pathway Symptoms on Quality of Life in Chronic Episodic Migraine

Effect of Trigeminal Pathway Symptoms on Quality of Life in Chronic Episodic Migraine

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Abnormal sleep latency and impaired function related to concentration issues may occur more frequently in patients with chronic vs episodic migraine.

Guidelines on the Use of OnabotulinumtoxinA for Chronic Migraine

Guidelines on the Use of OnabotulinumtoxinA for Chronic Migraine

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Researchers and pain experts formulated guidelines for the use of onabotulinumtoxinA for the management of chronic migraine.

OnabotulinumtoxinA Injections Reduce Frequency of Cluster Headaches

OnabotulinumtoxinA Injections Reduce Frequency of Cluster Headaches

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Injections of onabotulinumtoxinA at the sphenopalatine ganglion provide long-term relief for patients with chronic cluster headaches.

Guideline for Diagnosis and Treatment of Idiopathic Intracranial Hypertension

Guideline for Diagnosis and Treatment of Idiopathic Intracranial Hypertension

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The European Headache Federation has issued recommendations on how to best diagnose and treat idiopathic intracranial hypertension.

Persistent Poststroke Headache: Finding Its Place in Stroke Aftercare

Persistent Poststroke Headache: Finding Its Place in Stroke Aftercare

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The continued observation of this delayed headache syndrome may point to a different pathophysiology from tension-type headache or acute poststroke headache.

High-Flow Oxygen Therapy as Effective as Sumatriptan for Cluster Headaches

High-Flow Oxygen Therapy as Effective as Sumatriptan for Cluster Headaches

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The effectiveness, tolerability, and use of inhaled oxygen compared with injectable sumatriptan was examined by utilizing a patient reported survey.

Increased Risk for Suicide Attempts in Patients With Status Migrainosus

Increased Risk for Suicide Attempts in Patients With Status Migrainosus

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Investigators examine risk factors associated with suicide attempt in patients with status migrainosus

Headache Specialists Dissatisfied With Emergency Department Headache Care

Headache Specialists Dissatisfied With Emergency Department Headache Care

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Investigators used a survey to better understand whether headache specialists adhere to headache management protocols and the strategies used to prevent ED visits for headache.

Pediatric Migraine: Evidence-Based Alternative Management

Pediatric Migraine: Evidence-Based Alternative Management

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Recent high-quality clinical trial evidence has demonstrated that medications commonly prescribed for migraine prevention in pediatric patients were not superior to placebo for reducing headache symptoms.

Expert Opinion: CGRP Receptor Antagonist Use in Pediatric Patients With Migraine

Expert Opinion: CGRP Receptor Antagonist Use in Pediatric Patients With Migraine

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Recommendations on the use of these agents in this patient population were published in a Views and Perspectives paper in the journal Headache.

Erenumab Superior to Placebo for Reducing Migraine Disability, Improving HRQoL

Erenumab Superior to Placebo for Reducing Migraine Disability, Improving HRQoL

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A significantly lower percentage of patients receiving a 70-mg or 140-mg dose of erenumab had severe disability during treatment compared with placebo.

Insomnia May Increase Risk for Migraine and Non-Migraine Headache

Insomnia May Increase Risk for Migraine and Non-Migraine Headache

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Individuals who experience insomnia may be more likely to have migraine and non-migraine headache compared with those without insomnia.

Effects of Mindfulness Therapy, Pharmacologic Prophylaxis on Catecholamine Levels in Migraine

Effects of Mindfulness Therapy, Pharmacologic Prophylaxis on Catecholamine Levels in Migraine

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Mindfulness-based practices and treatment programs may be associated with similar changes in plasma levels of catecholamines compared with pharmacologic prophylaxis in patients with migraine and medication overuse headache.

Involvement and Diagnosis of Myofascial Trigger Points in Migraine, Tension-Type Headache

Involvement and Diagnosis of Myofascial Trigger Points in Migraine, Tension-Type Headache

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Patients with tension-type or migraine headaches often exhibit myofascial trigger points, but the involvement of these trigger points in the pathophysiology of these conditions is not well understood.

Consensus Statement: Estrogen and Progestogen Treatment for Migraines

Consensus Statement: Estrogen and Progestogen Treatment for Migraines

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Further research is needed to assess the relationship between estrogen and progestogens on migraines in women.

Familial Hemiplegic Migraine Attacks May Be Associated With Cortical Swelling

Familial Hemiplegic Migraine Attacks May Be Associated With Cortical Swelling

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Investigators examined imaging data of 4 patients with familial hemiplegic migraine attacks subtype 2 to determine distinct imaging finds.

Pain Characteristics and Diagnosing Intracranial Vertebral Artery Dissection

Pain Characteristics and Diagnosing Intracranial Vertebral Artery Dissection

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Investigators sought to determine characteristics associated with intracranial vertebral artery dissection-related headache.

Low Serum Levels of Thyroid Stimulating Hormone Linked With Prolonged Migraine

Low Serum Levels of Thyroid Stimulating Hormone Linked With Prolonged Migraine

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Investigators examined the role of thyroid function in patients with migraine and whether there is an association with severity of symptoms with thyroid hormone levels.

Pretreatment With Sumatriptan Can Reduce Cilostazol-Induced Headaches

Pretreatment With Sumatriptan Can Reduce Cilostazol-Induced Headaches

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Investigators assess whether pretreatment with sumatriptan prevents headaches induced by cilostazole in healthy volunteers.

Poor Sleep Quality Common in People With Migraine and Probable Migraine

Poor Sleep Quality Common in People With Migraine and Probable Migraine

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Poor sleep quality is prevalent among patients with probable migraine and is associated with an exacerbation of probable migraine symptoms.

Ajovy Injection Approved for Migraine Prevention in Adults

Ajovy Injection Approved for Migraine Prevention in Adults

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The primary efficacy endpoint was the mean change from baseline in the monthly average number of headache days of at least moderate severity during the 3-month treatment period.

Galcanezumab May Result in Functional Improvements in Migraine

Galcanezumab May Result in Functional Improvements in Migraine

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Galcanezumab treatment may result in functional improvements and a reduction in the impact of headaches on quality of life in patients with migraine.

Reduced Habituation to Painful Stimuli May Characterize the Preictal Phase in Migraine

Reduced Habituation to Painful Stimuli May Characterize the Preictal Phase in Migraine

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The preictal phase may be characterized by a reduction in habituation in patients with migraine.

Locally Asymptomatic Ischemic Stroke May Present as Migraine Aura

Locally Asymptomatic Ischemic Stroke May Present as Migraine Aura

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Local ischemia after an acute ischemic stroke may trigger a widely migrating cortical wave of spreading depolarization, which may present as migraine aura.

Asthma and Allergic Rhinitis May Be Risk Factors for Migraine in Adolescents

Asthma and Allergic Rhinitis May Be Risk Factors for Migraine in Adolescents

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Adolescents who have asthma or allergic rhinitis may be at higher risk for developing migraine.

Gender Differences in the Epidemiology of Migraine

Gender Differences in the Epidemiology of Migraine

Men were not only less likely to consult a doctor for their migraines than women, they were also less likely to be diagnosed with migraine.

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