Generic Name and Formulations:
Hydrochlorothiazide 12.5mg; caps.
Indications for MICROZIDE:
12.5mg once daily; usual max 50mg/day.
Anuria. Sulfonamide allergy.
Renal or hepatic impairment. Arrhythmia. Diabetes. Gout. Asthma. SLE. Parathyroid disease. Excessive fluid loss. Monitor electrolytes, BUN (if high). Potassium supplements or K+-sparing diuretics may be needed. Discontinue if electrolyte disorders develop rapidly. Elderly. Pregnancy (Cat.B). Nursing mothers: not recommended.
May cause digitalis, lithium toxicity. Adjust antidiabetic, antigout medications. ACTH, corticosteroids, amphotericin B increase hypokalemia risk. Orthostatic hypotension with alcohol, CNS depressants. Antagonized by NSAIDs. May potentiate nondepolarizing muscle relaxants. May antagonize norepinephrine. May interfere with parathyroid tests. Additive effects with other antihypertensives.
Electrolyte disorders (esp. hypokalemia), hyperglycemia, hyperuricemia, photosensitivity, orthostatic hypotension, GI disturbances, adverse lipid values; acute myopia, angle-closure glaucoma (discontinue if occurs).
Clinical Pain Advisor Articles
- Manual Therapy vs Opioids for Management of Shoulder, Spine Pain
- Opioids: Clinician Concern and Prescribing Practices
- Screening for Hyperglycemia Prior to Steroid Injections for Chronic Pain
- Ensuring Safety During Long-Term Opioid Therapy
- Intervention by Pharmacists May Effectively Reduce Use of Inappropriate Medications in the Elderly
- Serum Vitamin D Levels and Risk for Migraine
- Rimegepant Orally Dissolving Formulation Provides Rapid Relief From Acute Migraine
- Updated Evidence-Based Recommendations for Buprenorphine Treatment
- Business Degree Increasingly Useful for Doctors
- PainDETECT May Not Be Optimal to Detect Neuropathic Components of Orofacial Pain
- Kinesiophobia May Be Associated With Greater Cutaneous Allodynia in Migraine
- CDC: 8.8% of Individuals in the United States Uninsured in First Half of 2018
- Patient Experiences Shed Light on Diagnostic Errors
- Topical Migraine Trigger Point Treatment as Effective as Injection
- Wikipedia in Medical Education: An Educator's Guide to Crowdsourcing