Methotrexate

Quality of Life in Rheumatoid Arthritis Improved With Filgotinib

Quality of Life in Rheumatoid Arthritis Improved With Filgotinib

By

The results of 2 randomized controlled trials showed that filgotinib improved quality of life when given in combination with methotrexate or as monotherapy in rheumatoid arthritis.

Methotrexate Response in RA may be Predicted by Gene Expression

Methotrexate Response in RA may be Predicted by Gene Expression

Increased baseline gene expression in peripheral blood may be associated with improved clinical response to methotrexate in rheumatoid arthritis.

Kevzara Injection Gets FDA Approval for Rheumatoid Arthritis

Kevzara Injection Gets FDA Approval for Rheumatoid Arthritis

By

Regeneron and Sanofi announced that the FDA has approved Kevzara (sarilumab) injection to treat adults with moderate to severe rheumatoid arthritis.

Additional Tool for Juvenile Dermatomyositis Diagnosis: Muscle MRI

Additional Tool for Juvenile Dermatomyositis Diagnosis: Muscle MRI

By

Muscle MRI may complement a physician's objective assessment in juvenile dermatomyositis, although negative MRI findings should not preclude treatment continuation.

Guidelines for Biologics Use in Lupus by International Panel

Guidelines for Biologics Use in Lupus by International Panel

By

A multidisciplinary group of international experts has released recommendations for the use of biologics in patients with systemic lupus erythematosus.

Rheumatoid Arthritis Treatment Initiated Early on Shows Good Long-Term Outcomes

Rheumatoid Arthritis Treatment Initiated Early on Shows Good Long-Term Outcomes

By

Patients with RA who were treated in the first 6 months had a lower risk of death.

Remicade Biosimilar FDA-Approved

Remicade Biosimilar FDA-Approved

By

The FDA has approved Renflexis, the second approved biosimilar to Remicade.

Rheumatoid, IBD Treatments and Risk of Breast Cancer Recurrence

Rheumatoid, IBD Treatments and Risk of Breast Cancer Recurrence

No statistically significant association was found between MTX or anti-TNF use and breast cancer recurrence.

Lowering Methotrexate Dosage Not Supported in RA Patients Initiating Adalimumab Therapy

Lowering Methotrexate Dosage Not Supported in RA Patients Initiating Adalimumab Therapy

By

While the MUSICA trial did not establish noninferiority for a lower dosage of MTX when combined with adalimumab, it may be an appropriate option for patients who require a reduction due to MTX toxicity.

Benefits of Intensive Pain Control in Early Rheumatoid Arthritis

Benefits of Intensive Pain Control in Early Rheumatoid Arthritis

By

Much of the disability associated with RA relates to the pain secondary to inflammatory joint inflammation.

Sign Up for Free e-Newsletters