Methadone Maintenance Therapy Associated With Greater Access to Physician Care in HCV-Positive Drug UsersMay 07, 2018
The investigators suggest that enrollment in a methadone maintenance therapy program may be helpful in providing access to HCV care in people who inject drugs.
All 3 opioid-dependence pharmacotherapies — methadone, buprenorphine, and oral naltrexone — were associated with reductions in inpatient substance abuse treatment.
Methadone exposure in utero was shown to increase the risk for neonatal abstinence syndrome compared with buprenorphine exposure.
A review of several published studies showed that the evidence did not support dose limitations or arbitrary caps of buprenorphine or methadone as a strategy to address benzodiazepine or other CNS depressant use in MAT-treated patients.
The FDA has recently issued a report advising against the use of buprenorphine and methadone medications in patients taking benzodiazepines and/or other central nervous system depressants.
WHO has updated its Essential Medicines List to include new recommendations on which antibiotics to use for common infections and serious conditions.
A ketamine regimen is superior to methadone, or ketamine combined with methadone, in alleviating neuropathic pain and associated sensory changes.
Practices pertaining to the use of methadone to facilitate opioid weaning in pediatric patients are widely heterogeneous.
Polymorphism at the level of drug receptors, transporters, or other proteins involved in drug metabolism or action may have an impact on the effect of a drug.
Throughout 2016, the FDA has announced requirements for manufacturers to create new product labeling information for a variety of opioid medications.
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