IASP 2018

Capsaicin 8% Patch Effective, Safe for Localized Peripheral Neuropathic Pain

Capsaicin 8% Patch Effective, Safe for Localized Peripheral Neuropathic Pain

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Capsaicin 8% patch has demonstrated efficacy and safety in improving pain, allodynia, and hyperalgesia associated with a wide range of localized peripheral neuropathy types.

Early Pain Reduction With Duloxetine May Predict Long-Term Efficacy in Knee Osteoarthritis

Early Pain Reduction With Duloxetine May Predict Long-Term Efficacy in Knee Osteoarthritis

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Patients with osteoarthritis and knee pain who experience an early reduction in pain intensity when treated with duloxetine may experience long-term improvements in pain and quality of life from continued duloxetine intervention.

Medicinal Cannabis May Not Have Opioid-Sparing Effects in Chronic Noncancer Pain

Medicinal Cannabis May Not Have Opioid-Sparing Effects in Chronic Noncancer Pain

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Medicinal cannabis may not effectively reduce opioid use or pain interference in individuals with chronic noncancer pain.

Trends and Predictors of Mortality for US Opioid Overdoses from 2003 to 2014

Trends and Predictors of Mortality for US Opioid Overdoses from 2003 to 2014

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Most opioid overdose patients were male and lived in the Southern United States (39.3%).

Pregabalin and Celecoxib Reduced Need for Morphine After Lumbar Spine Surgery

Pregabalin and Celecoxib Reduced Need for Morphine After Lumbar Spine Surgery

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Patients who received pregabalin and celecoxib had significantly lower pain scores and fewer patient-controlled analgesia button pushes than those who did not.

Cannabis May Be Effective for Migraine Treatment

Cannabis May Be Effective for Migraine Treatment

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The growing body of research on marijuana and its effectiveness for pain management can be attributed to its recent legalization across multiple states in the United States.

Preemptive Tapentadol May Effectively Reduce Pain, Opioid Consumption After TKA

Preemptive Tapentadol May Effectively Reduce Pain, Opioid Consumption After TKA

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Preemptive tapentadol may safely and effectively reduce postoperative pain in patients undergoing total knee arthroplasty.

Pediatric Prescriptions for Tramadol Frequently Contraindicated

Pediatric Prescriptions for Tramadol Frequently Contraindicated

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Tramadol, although seldom prescribed in children, was found to be prescribed for almost half of children with contraindications for its use.

Duloxetine May Be Ineffective in Juvenile Primary Fibromyalgia

Duloxetine May Be Ineffective in Juvenile Primary Fibromyalgia

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Duloxetine may not be effective in treating juvenile primary fibromyalgia syndrome.

Sublingual Sufentanil May Be Safe and Effective for Short-Term Acute Pain Management

Sublingual Sufentanil May Be Safe and Effective for Short-Term Acute Pain Management

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Sufentanil sublingual tablets may be effective for the short-term postoperative or emergency department management of moderate to severe pain in patients from across the body mass index spectrum.

Lasmiditan May Be Effective for the Acute Treatment of Migraine

Lasmiditan May Be Effective for the Acute Treatment of Migraine

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The acute treatment of migraine with lasmiditan may be safe and associated with short-term freedom from headache pain and reductions in bothersome headache symptoms.

Oral Piroxicam Fast-Dissolving Tablets vs Sublingual Fentanyl for Bone Metastases-Related Pain

Oral Piroxicam Fast-Dissolving Tablets vs Sublingual Fentanyl for Bone Metastases-Related Pain

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Fast-dissolving oral piroxicam may represent an effective alternative to sublingual fentanyl for treating incidental breakthrough pain attacks caused by bone metastasis.

Parecoxib May Be Superior to Ketorolac for Oral Surgery-Associated Pain

Parecoxib May Be Superior to Ketorolac for Oral Surgery-Associated Pain

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Parecoxib may be effective for postoperative pain following oral surgery and may be associated with fewer side effects than ketorolac.

Duloxetine May Be an Effective Prophylactic for Episodic Migraines

Duloxetine May Be an Effective Prophylactic for Episodic Migraines

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Duloxetine may effectively prevent episodic migraine.

Sex Differences in Comorbid Chronic Pain and Depression Examined

Sex Differences in Comorbid Chronic Pain and Depression Examined

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Chronic neuropathic pain has a large impact on quality of life and often causes or increases depressive symptoms for both men and women.

Mirogabalin May Be Safe for Postherpetic Neuralgia and Diabetic Peripheral Neuropathic Pain

Mirogabalin May Be Safe for Postherpetic Neuralgia and Diabetic Peripheral Neuropathic Pain

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Mirogabalin may be efficacious and well tolerated in Asian individuals with postherpetic neuralgia or diabetic peripheral neuropathic pain.

Depression May Partially Mediate the Relationship Between PTSD and Opioid Misuse

Depression May Partially Mediate the Relationship Between PTSD and Opioid Misuse

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Depression may partially mediate the association between post-traumatic stress disorder and opioid misuse.

Anticonvulsants May Be Ineffective for Low Back, Lumbar Radicular Pain

Anticonvulsants May Be Ineffective for Low Back, Lumbar Radicular Pain

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Anticonvulsants may not effectively reduce pain or disability in patients with low back pain or lumbar radicular pain.

Ketamine Superior to Clonidine as an Adjunct to Epidural Steroid Injections for Low Back Pain

Ketamine Superior to Clonidine as an Adjunct to Epidural Steroid Injections for Low Back Pain

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Ketamine may be superior to clonidine as an adjunct to epidural steroid injection of triamcinolone for patients with chronic low back pain.

Few Studies on Pharmacotherapies for Postherpetic Neuralgia Report Adverse Events

Few Studies on Pharmacotherapies for Postherpetic Neuralgia Report Adverse Events

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In studies reporting on pharmacologic treatments for postherpetic neuralgia, few report the incidence of adverse events (AEs) or withdrawal rates due to AEs.

No Benefits Found in Adding Methylcobalamin to Pregabalin for Treating Postherpetic Neuralgia

No Benefits Found in Adding Methylcobalamin to Pregabalin for Treating Postherpetic Neuralgia

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Adding methylcobalamin to pregabalin therapy has no advantage for patients with postherpetic neuralgia.

Repeated Lidocaine Infusion Therapy Effective for Neuropathic Pain

Repeated Lidocaine Infusion Therapy Effective for Neuropathic Pain

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In patients with neuropathic pain conditions, low-dose lidocaine infusion therapy was found to be an effective treatment for short-term pain relief.

Allopurinol Demonstrates No Analgesic Effect for Fibromyalgia Pain

Allopurinol Demonstrates No Analgesic Effect for Fibromyalgia Pain

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Allopurinol did not provide pain relief for patients with fibromyalgia pain over the course of 30 days.

Combining Hyaluronic Acid With Platelet-Rich Plasma Injections for Primary Knee Osteoarthritis

Combining Hyaluronic Acid With Platelet-Rich Plasma Injections for Primary Knee Osteoarthritis

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Hyaluronic acid therapy may be more effective when supplemented with intra-articular platelet-rich plasma injections vs alone in treating primary knee osteoarthritis.

IASP 2018 Conference: Preview of Live Coverage

IASP 2018 Conference: Preview of Live Coverage

Clinical Pain Advisor will bring you live coverage of the 17th World Congress on Pain, held September 12 to 16, 2018, in Boston, Massachusetts.

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