Hyperalgesia

Pain Tolerance in Buprenorphine Maintenance Treatment

Pain Tolerance in Buprenorphine Maintenance Treatment

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Buprenorphine maintenance treatment for opioid dependence may result in hyperalgesia and prevent morphine-associated antinociception.

Chronic Pain in Pachyonychia Congenita May Have Neuropathic Origin

Chronic Pain in Pachyonychia Congenita May Have Neuropathic Origin

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Chronic pain experienced by patients with pachyonychia congenita may be caused by damage to the peripheral nerve fibers, with the hyperalgesia and allodynia observed in affected regions likely to be manifestations of peripheral sensitization.

Elevated Interictal Oxytocin Associated With Affective Pain in Chronic Migraine

Elevated Interictal Oxytocin Associated With Affective Pain in Chronic Migraine

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The higher interictal levels of oxytocin observed in patients with chronic migraine compared with unaffected individuals may contribute to the affective component of experimental pain.

Hypoalgesia, Hyperalgesia Linked to Multiple Sclerosis Lesion Location

Hypoalgesia, Hyperalgesia Linked to Multiple Sclerosis Lesion Location

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In patients with multiple sclerosis, lesions in the right dorsolateral prefrontal cortex and posterior periventricular area may be associated with hypo and hyperalgesia.

Intraoperative Naloxone Reduces Remafentanil-Induced Postoperative Hyperalgesia

Intraoperative Naloxone Reduces Remafentanil-Induced Postoperative Hyperalgesia

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Intraoperative low-dose naloxone reduced postoperative hyperalgesia but had no effect on pain when combined with high-dose remifentanil for elective thyroid surgery.

Secondary Hyperalgesia Mediated by Nociceptive and Other Sensory Pathways

Secondary Hyperalgesia Mediated by Nociceptive and Other Sensory Pathways

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The effects of central sensitization extend beyond nociceptive pathways to other sensory modalities.

Hyperalgesia Can Be Socially Transmitted Via Olfactory Cues

Hyperalgesia Can Be Socially Transmitted Via Olfactory Cues

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This study sheds light on the role of social and environmental cues in pain pathogenesis and has implications for the treatment of chronic pain patients.

Opioids Prolonging Hyperalgesia?

Opioids Prolonging Hyperalgesia?

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Involvement of microglia, inflammation

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