Preexisting mental health conditions, use of tramadol, and higher number of dispensed tablets were associated with an increased risk for opioid overdose in adolescents.
Investigators extracted data from 8 waves of the Monitoring the Future study, which annually surveyed approximately 17,000 US high school students starting in 1975.
A $260 million settlement in an opioid lawsuit was reached between two Ohio counties and four drug companies, just hours before opening arguments were to begin in a landmark federal trial over responsibility for the U.S. opioid crisis.
The U.S. opioid epidemic cost the nation’s economy $631 billion from 2015 through 2018.
The Canadian Research Initiative in Substance Misuse National Injectable Opioid Agonist Treatment Steering Committee has released a new guideline on the use of injectable opioid agonist treatment for opioid use disorder.
There is enormous need for well-trained providers who are educated in treating opioid use disorder.
The FDA and the Drug Enforcement Administration (DEA) have issued joint warning letters to several website operators that have been illegally selling opioid medications online.
Treatment with lofexidine may provide better control of the symptoms of opioid withdrawal syndrome compared with placebo.
Receipt of prescription opioids is associated with an increased risk for death and hospitalization, especially in patients with lower estimated glomerular filtration rates.
Fentanyl and fentanyl analogues may cause rapid death through airway compromise and severe muscle rigidity.