In utero exposure to opioids is associated with higher risks for short- and long-term adverse outcomes, including preterm birth and neurodevelopmental and physical health disorders in children.
On average, 45% of callers reporting current heroin use were denied an appointment with a buprenorphine provider. More of those paying cash were offered an appointment, compared with those covered by Medicaid.
Two companies have been issued warning letters by the Food and Drug Administration (FDA) for illegally selling unapproved, misbranded kratom-containing drug products.
Higher rates of pulmonary complications are more likely to occur in patients who receive high total doses of naloxone for the treatment of opioid overdose in an out-of-hospital setting.
Children of parents with opioid use had a 2-fold increased risk for suicide attempts vs children of matched controls.
For as much as we know about the dangers of opioids, relatively little is known about how environmental factors might influence opioid-related mortality. Does cold weather increase the risk of fatal overdose?
Galantamine, which was found to reduce cocaine use in patients treated with methadone for opioid use disorder, may also be effective in reducing the use of nonprescribed opioids in this population.
The US Food and Drug Administration has provided fast-track approval for the nonclinician use of Evzio, an easy-to-use autoinjectable device with a single dose of naloxone for the reversal of opioid overdose.
Patients surveyed following surgery and only a small ‘rescue’ opioid Rx postop
The Opioid Safety Initiative has been effective for decreasing opioid prescriptions among patients undergoing total knee arthroplasty.