HealthDay News — Lipid profiles seem to be associated with tendon health, according to a review published online in the British Journal of Sports Medicine.

Benjamin J. Tilley, from Monash University in Australia, and colleagues conducted a systematic review and meta-analysis to examine whether lipid levels are associated with abnormal tendon structure or the presence of tendon pain. A total of 17 studies, with 2,612 participants, were included in the review.

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The researchers found that significantly higher total cholesterol, low-density lipoprotein cholesterol, and triglycerides were seen among those with altered tendon structure or tendon pain (mean difference values of 0.66, 1, and 0.33 mmol/L, respectively). 

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In addition, they had lower high-density lipoprotein cholesterol (mean difference value of −0.19 mmol/L).

“The results of this review indicate that a relationship exists between an individual’s lipid profile and tendon health,” the authors wrote. “However, further longitudinal studies are required to determine whether a cause and effect relationship exists between tendon structure and lipid levels.”


1. Tilley B, Cook J, Docking S, Gaida J. Is higher serum cholesterol associated with altered tendon structure or tendon pain? A systematic review. British Journal of Sports Medicine. 2015:bjsports-2015-095100. doi:10.1136/bjsports-2015-095100.