A hospital-based cohort study found sex heterogeneity in the severity of osteoarthritis symptoms in type 2 diabetes, and an association between insulin treatment and pain severity in men.
The randomized, double-blind, controlled trial (N=24,081) included patients with rheumatoid arthritis or osteoarthritis who required chronic NSAID treatment.
The results of 2 randomized controlled trials showed that filgotinib improved quality of life when given in combination with methotrexate or as monotherapy in rheumatoid arthritis.
In clinical trials, treatment with Durolane resulted in greater reduction in Visual Analog Scale (VAS) pain scores at 3 and 6 months compared to Synvisc One (hylan G-F 20; Sanofi Genzyme).
Patients with knee osteoarthritis who can best benefit from treatment with intra-articular hyaluronic acid injections include patients with high levels of knee pain, younger individuals, persons with a high body mass index, and individuals with less severe structural damage.
The effects of glucosamine supplements in the treatment of patients with painful temporomandibular joint osteoarthritis were not superior to the effects of ibuprofen taken 2 to 3 times per day.
