FDA Committees Vote on Novel Opioid for Chronic Low Back Pain
As a result of the vote, Nektar has decided to withdraw the New Drug Application for oxycodegol and to cease further development of the product.
Musculoskeletal Pain
MUSCULOSKELETAL PAIN
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Treatment Guidelines Updated for Hand, Hip, Knee Osteoarthritis
Based on the available evidence, the authors made strong recommendations for exercise.
Zilretta Labeling Updated to Include Repeat Administration Information for OA Knee Pain
The product label for Zilretta includes an updated Limitation of Use.
Decline in Prescribed Opioids Noted From 2014 to 2016 in the United States
From 2014 to 2016, there was a decrease in the proportion of U.S. adults who were prescribed opioids, with a larger decrease seen for those who reported moderate or more severe pain versus less-than-moderate pain.
Patients Find Benefits in Use of Checklist Prior to Induction of Anesthesia
Anesthesia providers rate patient discomfort from use of checklists prior to anesthesia induction much higher than do patients.
How a Pain Clinic Law Changed Prescribing Behaviors
Researchers conducted a study analyzing the effects of the law on prescriber cessation and modification responses, noting that cessation behaviors can have a dramatic effect on patients, who may transition to illicit opioids if they lack access to a prescriber.
Neurodynamic Mobilization Improves Hand OA Pain Hypersensitivity
Researchers assessed and compared the effectiveness of neurodynamic mobilization techniques with passive robotic physiologic movement for patients with hand osteoarthritis.
Outcomes Worse for Rural Residents With Chronic Conditions
Rural Medicare beneficiaries with complex chronic conditions have higher preventable hospitalization and mortality rates than their urban peers, which is partially explained by reduced access to specialists.
NASEM Report Provides Framework for Developing Opioid Prescribing Guidelines
In an effort to further address the current opioid crisis, the FDA contracted the NASEM to examine existing opioid prescribing guidelines and to help outline the type of research needed to fill the gaps in evidence.
Incident NSAID Use May Increase Major Bleeding Risk in AF
The use of nonsteroidal anti-inflammatory drugs in patients with atrial fibrillation was found to be associated with an increased risk for major and clinically relevant nonmajor bleeding.
New 3 Digit Suicide Prevention Hotline to Be Established
A new three-digit number in the United States to contact a suicide prevention hotline is being created by federal officials.
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