HealthDay News — Patients with chronic tension-type headache (CTTH) have impairments in cognitive ability and neuroendocrine dysfunction, according to a study published in Pain Practice.1

Ping Qu, from the Anhui Medical University in Hefei, China, and colleagues evaluated cognitive impairment in patients with CTTH and healthy controls. Additionally, hormonal changes in the hypothalamus-pituitary-adrenal axis, the hypothalamus-pituitary-thyroid axis, and gonadotropin-releasing hormone were assessed.

The researchers found that significant cognitive impairment and neuroendocrine dysfunction were present in the CTTH patients, compared to the healthy controls. Changes in neuroendocrine hormones were seemingly involved in symptoms of CTTH.

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“Intervention with the neuroendocrine state may be a strategy for CTTH treatment,” the authors write.

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  1. Qu P, Yu JX, Xia L, Chen GH. Cognitive performance and the alteration of neuroendocrine hormones in chronic tension-type headache. Pain Pract. 2017. doi: 10.1111/papr.12574